Sample_ID TCGA-4Z-AA80-01A-21-A458-20 TCGA-4Z-AA82-01A-21-A458-20 TCGA-4Z-AA89-01A-21-A458-20 TCGA-BT-A0YX-01A-21-A209-20 TCGA-BT-A20U-01A-21-A209-20 TCGA-BT-A20V-01A-21-A209-20 TCGA-BT-A20X-01A-21-A209-20 TCGA-BT-A2LD-01A-21-A23Y-20 TCGA-BT-A42E-01A-21-A457-20 TCGA-C4-A0F1-01A-21-A209-20 TCGA-C4-A0F7-01A-21-A209-20 TCGA-CU-A0YN-01A-11-A209-20 TCGA-CU-A72E-01A-21-A458-20 TCGA-DK-A2I2-01A-21-A209-20 TCGA-E7-A7XN-01A-21-A459-20 TCGA-E7-A97P-01A-21-A459-20 TCGA-FD-A3B4-01A-21-A209-20 TCGA-FD-A3B5-01A-21-A23Y-20 TCGA-FD-A3N5-01A-21-A23Y-20 TCGA-FD-A3N6-01A-21-A23Y-20 TCGA-FD-A43Y-01A-31-A457-20 TCGA-G2-A2ES-01A-21-A209-20 TCGA-G2-A3IB-01A-21-A23Y-20 TCGA-GC-A3I6-01A-21-A23Y-20 TCGA-GD-A3OS-01A-21-A23Y-20 TCGA-GU-A766-01A-21-A458-20 TCGA-K4-A4AC-01A-41-A457-20 TCGA-PQ-A6FI-01A-21-A458-20 TCGA-XF-A8HE-01A-21-A459-20 TCGA-XF-A8HH-01A-21-A459-20 TCGA-XF-A9SJ-01A-21-A457-20 TCGA-XF-A9T4-01A-21-A457-20 TCGA-XF-A9T8-01A-21-A457-20 TCGA-XF-AAME-01A-21-A458-20 TCGA-XF-AAMH-01A-21-A458-20 TCGA-XF-AAMT-01A-21-A458-20 TCGA-XF-AAN2-01A-21-A458-20 TCGA-XF-AAN5-01A-21-A458-20 TCGA-YC-A89H-01A-21-A458-20 TCGA-ZF-A9RD-01A-21-A457-20 TCGA-ZF-A9RG-01A-11-A457-20 TCGA-ZF-AA4W-01A-21-A459-20 TCGA-ZF-AA53-01A-21-A459-20 14-3-3_beta-R-V -0.0240558 -0.22346 -0.0647443 -0.348752 -0.193025 -0.0153371 0.0340779 0.0619944 -0.0709367 -0.0689546 -0.00744901 0.0191299 -0.0779439 -0.333084 0.0648006 -0.129701 0.287012 0.055299 -0.0467089 0.275451 0.141011 -0.170405 0.0136289 0.0571164 0.22546 0.11509 0.239363 0.0784085 0.0766165 0.019874 -0.0642408 0.109962 0.185036 0.06725 -0.119255 0.207919 -0.0166111 -0.0236495 -0.192441 0.0729624 0.182107 0.037778 -0.00907305 14-3-3_epsilon-M-C 0.00419036 -0.078832 -0.0436487 0.0256431 -0.0519642 0.0190701 -0.105505 0.113089 0.25592 -0.0538174 -0.184403 0.320108 0.188618 0.137294 0.43608 0.346574 0.0289769 -0.026663 0.133057 0.1898 -0.0852711 -0.0612963 0.0997085 -0.106797 -0.00475983 0.0180432 0.151681 -0.00210372 0.032182 -0.00251772 0.0355621 0.0775961 -0.0100107 0.00453067 0.215432 -0.0952739 0.165182 0.214893 0.110508 0.160813 0.121973 0.156901 0.199431 14-3-3_zeta-R-V -0.259224 0.419081 0.180996 -0.657763 -0.315993 0.168576 0.165025 1.19515 -0.102517 0.411713 -0.23763 -0.0808246 0.0232643 0.1854 0.000288123 0.213927 -0.258829 0.16077 -0.0134495 1.34216 -0.207171 -0.270663 0.508133 0.12848 0.040879 0.151184 1.12159 0.228485 0.483909 0.57711 0.162209 -0.321268 0.508506 0.630014 0.198029 -0.206373 -0.0204779 0.256197 0.501908 -0.0505269 -0.222479 0.808776 -0.0320991 4E-BP1-R-V -0.103331 0.308319 0.0510106 -0.0563675 -0.130359 0.590724 0.811531 -0.211664 0.307557 0.858618 0.818844 -0.0792067 0.265149 0.646092 0.101536 0.432844 -0.328377 -0.141717 0.409437 0.446976 -0.470884 0.38366 0.663462 0.330626 -0.228311 -0.0827156 0.142814 1.10158 0.358084 -0.285109 -0.152919 0.258549 0.434291 0.138429 0.24647 -0.969402 -0.0933231 0.0683041 -0.149227 0.148567 -0.303307 0.42804 0.833513 4E-BP1_pS65-R-V 0.181644 0.510663 -0.0164036 0.0830374 -0.380024 -0.249856 -0.407412 0.112067 -0.0618754 0.119804 0.262142 -0.281255 -0.142885 0.171506 -0.0756809 0.0555756 0.119339 -0.0692016 0.727515 -0.152242 -0.325779 -0.14471 0.518505 -0.25354 0.590309 0.347081 0.0911246 0.449155 -0.253263 0.0439873 -0.254717 0.243739 -0.166504 -0.136207 -0.0715417 0.21381 -0.114926 0.0519335 -0.0635343 0.0129469 -0.36776 -0.164276 0.443505 4E-BP1_pT37_T46-R-V 0.428464 0.200173 -0.111003 0.114988 -1.40346 -0.323545 -1.06042 0.701933 -0.20342 0.342559 0.144322 -1.04775 -0.593782 -0.374823 -0.737852 -1.05203 -0.658767 -0.773755 -0.986601 -1.33357 -0.626569 -1.00389 1.15682 0.0653361 0.933724 0.23486 -0.541467 0.89691 -0.75443 -0.0872753 -0.362166 0.0958807 0.325546 0.0408978 -0.257629 -0.0570857 0.0131671 -0.529605 0.0333372 -0.0901824 -0.684202 -0.946653 0.915389 4E-BP1_pT70-R-C 4E-BP1_pT70-R-V 0.205349 0.206766 -0.0141648 0.383377 -0.252833 0.126685 -0.103441 0.495285 -0.0742542 -0.115049 0.0969094 -0.0820815 -0.28598 -0.120557 0.266042 0.363937 -0.0937364 0.0235415 0.0651381 -0.0827132 -0.0837499 -0.00345509 0.250365 0.0484441 -0.0160723 0.680928 0.102126 0.623717 0.249135 -0.0287275 -0.12011 0.154883 0.275268 0.449105 -0.161155 -0.0940654 -0.0625243 -0.0337765 -0.0910157 0.170599 -0.218439 0.28407 1.01266 53BP1-R-C 53BP1-R-E 0.738733 -0.194629 0.716741 -0.662519 0.272228 0.156615 0.103558 -0.794698 -0.286457 -0.217872 0.0253704 -1.98866 0.102375 -0.612481 -0.248466 -0.114587 -1.25426 0.480513 -0.338744 -0.501752 -0.398535 -0.624639 -0.868649 -0.0765919 -0.765494 -0.990976 -0.745763 -0.377186 -1.24203 -0.351318 0.0979478 0.174424 -1.5875 -1.16858 0.394277 -0.796962 0.0547906 -0.848661 0.0615225 0.0281967 -0.354354 -1.52308 0.221787 53BP1-R-V A-Raf-R-V 0.0283561 0.175457 0.0674324 0.198719 0.0366698 0.196975 0.0662465 0.397286 0.061778 -0.208715 -0.311639 -0.224052 -0.0291793 0.396241 0.361148 0.226893 -0.0121893 0.0993236 0.272598 -0.0249777 -0.35221 0.206601 -0.426188 0.3207 -0.375805 0.0954044 0.0610133 0.095171 0.0291325 -0.0688617 0.222992 0.226688 -0.000482156 0.0549231 -0.266221 -0.154713 0.0486589 0.198502 -0.188608 0.386398 0.0667162 -0.106509 0.313569 A-Raf_pS299-R-C 0.164522 0.0406985 0.15837 0.485557 -0.197734 -0.0666032 -0.0778605 0.00464615 0.0367756 -0.135051 -0.305646 0.367538 0.0780072 -0.122118 0.0281936 -0.0714694 -0.0865919 -0.0791813 -0.0984371 -0.0536013 -0.482826 0.110771 0.627033 -0.187845 0.670438 0.0121358 -0.137331 0.0218185 -0.437501 0.0745144 0.687311 -0.0182044 -0.254682 0.230626 0.139493 -0.0844348 -0.0145568 -0.12384 0.605479 -0.0974607 -0.740412 -0.147159 0.151528 ACC1-R-C ACC1-R-E 1.05329 -0.166355 0.237369 -0.643085 0.322277 0.0334264 0.509151 -0.69822 0.0725251 -0.181114 0.197372 -1.20158 0.184866 1.07651 -0.379538 0.553357 -0.837365 1.11745 0.0821769 -0.65169 -0.325854 -0.468587 -0.383302 0.0991451 -1.74685 0.757408 -0.439612 0.378338 0.889375 0.155817 -0.0116501 -0.713598 0.677044 0.614968 0.277348 -0.537198 -0.140034 -0.079791 -0.0712389 0.047354 -0.859293 0.500357 0.005049 ACC_pS79-R-V 1.05512 -0.129805 0.205996 0.240341 -0.202618 -0.170389 0.0276444 -1.11295 -0.102555 -0.0214246 0.495267 -1.5634 -0.472658 0.588757 -0.775596 -0.588176 -0.6956 1.37143 -0.324168 -1.12474 -0.0761173 0.0311895 -0.396591 -0.0546198 -1.78971 0.413963 -0.336229 0.255721 0.188666 0.310725 0.0293138 -0.173957 0.127243 0.32674 0.128536 -0.591068 0.00472747 -0.202838 -0.149562 -0.0308505 -0.714735 -0.00819286 -0.0935853 ACVRL1-R-C -0.229727 0.0859149 -0.283791 -0.171393 0.205457 -0.0198422 0.181489 0.326635 -0.0734964 -0.0540703 0.0308666 0.455015 -0.0973346 0.298978 0.189678 -0.0069818 1.01537 -0.0305584 0.175116 -0.0132432 0.292468 -0.0734163 0.14544 -0.183039 0.231254 0.29552 0.0476942 0.124178 0.100529 0.0496985 -0.117965 -0.211537 0.335333 0.0766854 -0.220358 0.816517 -0.14128 0.061385 -0.17487 -0.128008 0.238982 0.458226 0.15635 ADAR1-M-V 0.0322257 -0.162223 0.00361188 -0.495521 -0.427625 0.664125 0.786259 -0.500001 0.0760941 0.405178 0.329021 -1.13624 -0.0497064 -0.933042 0.0377052 0.134103 -0.627825 -0.038774 -0.491109 -0.213562 -0.313106 -0.13934 -0.60121 -0.195228 -0.889693 -0.237396 -0.151079 -0.00544746 0.0391856 -0.00347319 0.0382116 -0.105977 -0.213599 -0.168891 0.104665 -0.0216049 0.104531 -0.188573 -0.0523465 -0.0058075 -0.0227266 -0.0220268 -0.0133264 AMPK_alpha-R-C -0.100208 -0.0166637 0.297732 -0.262211 0.123696 0.327005 0.00329398 -0.404854 -0.141967 0.343269 0.206259 -0.596901 0.357964 0.135993 0.0257129 0.238491 0.342373 -0.0864006 -0.0702579 -0.219055 -0.0310025 -0.0975084 -0.522759 -0.0173983 -1.01288 0.140647 -0.0991453 -0.193525 0.100104 -0.227374 -0.141395 -0.2652 0.242545 -0.201351 -0.0373195 0.391266 -0.260499 -0.136577 -0.0953465 0.02955 -0.130056 0.206238 0.0267302 AMPK_pT172-R-V 0.32448 0.418643 0.617566 -1.05699 0.389739 0.485609 0.192476 -0.0300789 0.205032 0.465728 0.47432 -1.55042 0.371427 0.366804 0.103275 -0.0438725 0.598331 0.448055 0.754237 0.0951734 0.346748 -0.629075 -0.0932634 0.604957 -1.96951 0.183259 0.0655644 0.00483912 -0.389863 -0.149723 -0.128916 -0.230359 -0.616418 -0.260812 0.0906923 -0.249053 0.0331509 -0.112335 -0.017465 0.546782 0.169241 -0.219391 0.282385 AR-R-V -0.0484281 -0.185645 0.344058 -0.0626252 0.283922 -0.245632 -0.197929 -0.115405 -0.0383951 -0.337056 0.608562 0.0645828 0.446069 -0.413742 -0.319887 -0.254576 0.270584 -0.358987 -0.405004 -0.196743 -0.443761 -0.395179 -0.371636 -0.592165 -0.0422954 -0.2415 -0.182644 -0.216087 -0.355886 -0.18136 -0.0907336 -0.112279 -0.154893 -0.465392 -0.0352771 -0.222143 -0.258376 -0.337196 -0.122252 -0.201146 -0.462794 -0.614545 -0.0517323 ARHI-M-E ARID1A-M-V -0.092943 -0.00253773 -0.024822 0.201554 -0.251325 0.284282 0.411823 -0.240801 -0.258549 0.111025 -0.168001 0.0613423 0.159874 0.042155 -0.24001 0.00518044 0.0601212 ARID1A-R-C -0.0259961 -0.325357 0.240606 0.0463505 0.649557 -0.413467 0.185407 -0.447422 -1.35844 -0.177004 0.115873 -1.79945 -0.000398461 0.149327 0.346603 -1.95051 -1.09528 0.702707 -0.748459 -0.182635 -0.428879 -0.693257 0.118805 -0.162119 -1.88465 0.0645275 ASNS-R-V 1.07317 0.44803 -0.110497 0.600494 0.144203 0.633544 -0.00329398 0.64396 0.203502 -0.613812 0.606322 -0.342179 -0.412456 0.843605 0.421204 0.488481 0.250416 0.47236 -0.362582 -0.105628 -0.55869 -0.0460341 0.302627 -0.182409 0.635247 0.98127 0.283536 -0.0763508 1.12218 -0.0610127 0.060743 -0.423638 -0.0450842 0.0127474 0.592033 -0.266113 0.0800842 0.360135 -0.158796 0.0760722 0.277399 0.216623 0.403591 ATM-R-C ATM-R-E 0.153637 -0.0416869 0.0549822 -0.349887 0.135316 0.0539255 -0.0596292 0.386377 -0.167268 -0.103598 -0.629409 -1.33534 0.217294 -0.658469 -0.370236 -1.30691 -0.911005 0.170682 0.0843705 0.427092 -0.33608 -0.13857 -0.165617 0.427169 -1.2227 0.0343366 ATM-R-V -0.594118 0.728844 0.956351 0.0946749 -0.234087 -0.269022 0.196019 -0.925914 0.571739 0.370608 -0.889551 -0.104311 -0.907576 -0.741799 -0.771243 0.803032 -1.22824 Acetyl-a-Tubulin-Lys40-R-C 0.092371 -0.391576 -0.454105 -0.358377 0.129587 -0.861138 -0.612872 0.904599 -1.45072 0.286981 -0.395858 -0.805814 0.198814 0.420919 0.048576 -0.967904 -0.339991 0.39321 0.203373 -0.869608 -0.475077 -0.405267 -0.453133 0.164004 -0.887443 0.456076 Acetyl-a-Tubulin-Lys40-R-E -0.773154 0.859126 -1.55071 -2.34596 -1.41441 0.827727 0.312983 -0.816325 -0.0387759 -0.388818 -0.00621374 0.43929 0.715942 -0.271578 0.0970261 -0.836373 -1.49941 Akt-R-V -0.141141 0.129509 0.243358 -0.201075 0.624121 -0.181672 0.434237 -0.548445 -0.0464813 0.530658 0.698031 -0.861064 0.247749 0.674011 -0.0617117 0.126887 -0.0884702 0.11555 0.138949 -0.801098 0.279452 0.0539744 -0.872931 0.180516 -1.99146 -0.419161 -0.061962 -0.20872 -1.70731 -0.0832971 0.222232 0.196179 -1.69379 -0.0517451 -0.247573 -0.00765552 -0.0450821 0.0781081 -0.0765291 0.174469 0.46329 -1.65048 0.0426265 Akt_pS473-R-V -0.106905 0.0902483 0.264687 1.46122 -0.597761 -0.797556 -0.498536 -0.0233302 -0.181594 0.483323 0.198893 0.243772 -0.450098 -0.0800649 -0.381342 -0.66893 0.166876 -0.418984 -0.506216 -0.461941 0.275689 -0.515083 0.293508 -0.0459295 0.146179 -0.120891 -0.55641 0.106661 -0.0857403 0.425643 -0.362763 0.393614 0.381698 0.738175 -0.458962 0.452015 0.0335524 -0.163471 0.862004 -0.234439 0.04198 -0.938448 -0.332669 Akt_pT308-R-V -0.296296 0.0589742 0.0367911 0.920507 -0.296082 -0.573368 -0.314802 -0.0730378 -0.0915632 0.799749 -0.265745 0.206774 -0.342946 0.0490434 -0.0530306 -0.236335 0.398466 -0.582665 -0.488787 -0.378253 -0.0696766 -0.555892 0.000730761 -0.538398 0.103193 -0.0565503 -0.193031 -0.136405 0.536139 0.163616 -0.178451 0.182601 1.0267 0.811248 -0.356787 0.716381 0.0353369 0.105832 0.563001 -0.11583 0.293173 -0.288259 -0.213329 Annexin-1-M-E -0.508406 1.09241 -0.0370301 0.76436 0.271057 0.963226 0.876484 1.39334 0.666575 1.21995 -0.73981 2.0184 -0.397132 0.547188 0.491023 1.55003 -0.408999 1.50784 0.51202 1.51381 0.329761 1.41486 0.537697 0.642858 -0.0830952 1.43853 2.23745 1.02728 1.28556 0.636584 0.101782 0.698921 1.92884 1.35453 1.6411 0.089566 0.516251 1.30536 0.543292 0.495575 0.881511 1.92067 0.552989 Annexin-1-M-V Annexin_VII-M-V 0.226267 -0.0703034 -0.150926 -0.0482183 -0.131535 -0.0979095 0.13489 0.171739 0.0208552 -0.305029 0.077044 0.568456 0.215353 -0.109318 0.15126 0.241395 0.206006 -0.000609894 0.482875 0.0209492 0.174431 0.139894 0.0739729 -0.0737379 -0.0595603 0.195429 -0.0971101 -0.0542683 0.230311 0.148969 0.206766 -0.105062 0.193838 0.120242 0.220954 0.260518 -0.00928259 0.194807 -0.258766 0.124232 0.454105 0.585163 0.263839 Axl-M-C Axl-R-V 0.0206338 0.268716 -0.140315 -0.0322721 -0.246255 -0.182517 -0.491162 -0.753169 -0.0386087 0.15579 0.169783 0.405219 -0.83314 -0.0981675 -0.084063 0.069521 -0.579454 B-Raf-M-C 1.06407 -0.354339 0.720025 -0.269661 -0.259202 0.253933 0.293977 -0.924605 -0.0881677 0.587376 1.13829 -1.64549 0.806161 -0.436573 -0.509553 0.0182506 -0.841556 0.44891 -0.365748 -0.700476 -0.356768 -0.234336 -1.25772 -0.428846 -1.28057 -1.12412 -0.317588 -0.262546 -1.7833 -0.0363569 0.0100276 -0.0240151 -2.0761 -1.69101 0.540562 -0.423232 0.222329 -1.19868 0.142197 -0.0186201 -0.0185052 -2.20214 -0.033191 B-Raf-M-E B-Raf-M-V B-Raf_pS445-R-V 1.17094 -0.243505 0.307239 0.146558 -0.413315 -0.221486 -0.346293 0.32876 -0.0902818 0.233719 0.775071 -0.299894 -0.12275 0.664922 0.0297433 -0.322754 -0.196984 0.144036 0.104124 -1.01218 -0.271312 -0.21112 -0.459522 -0.163363 -1.07603 -0.139239 -0.060029 0.230104 0.231344 -0.0876582 -0.0867626 0.0251421 0.127412 -0.0351814 -0.123292 -0.212921 0.171959 0.180444 0.309663 0.0547626 -0.323549 -0.0686646 0.088967 BRCA2-R-C -0.0156087 -0.0199991 0.446099 0.13471 0.246746 0.00965615 0.226139 -0.15893 0.243148 0.0263607 -0.00882226 0.236967 0.170913 -0.0861678 -0.539518 -0.0115604 -0.461801 BRD4-R-V 0.546964 -0.171957 0.266555 -0.402007 0.057526 0.135435 0.420022 -0.541724 0.181279 0.160529 0.181037 -1.04875 0.385118 -0.450442 -0.393202 -0.0957981 -1.02196 -0.338171 0.140121 0.190692 -0.21079 -0.025324 -0.0606931 0.222697 1.49669 -0.563095 -0.185395 -0.0951077 -0.798754 -0.581658 -0.160304 -0.098308 -1.20921 -0.636345 0.236218 -1.06096 0.140921 -0.351344 -0.0306221 0.187407 -0.124689 -1.28365 0.0449831 Bad_pS112-R-V 0.203333 0.215099 0.133204 0.362959 -0.469589 -0.625367 -0.0621587 0.0914098 -0.0669272 0.640284 0.260844 -0.843118 0.00576076 -0.204113 -0.252489 -0.299564 -0.0931823 0.332132 -0.29023 -0.154221 -0.310491 -0.0659369 0.495741 -0.0352052 -0.565093 -0.290443 -0.162111 -0.218183 -0.513467 -0.0695837 0.0573851 0.239903 -0.271829 -0.0395508 -0.142903 -0.372689 0.23119 -0.23933 0.0329789 -0.0825536 -0.0921242 -0.829804 -0.0750639 Bak-R-C -0.259174 -0.106259 -0.189872 0.102444 -0.158451 0.496074 0.483158 0.228337 0.357064 0.272693 0.0927096 -0.00978677 0.0691073 -0.0301085 -0.218002 -0.090335 0.0531052 0.00440978 0.012697 -0.0402519 -0.216368 0.237851 -0.0549478 -0.0404049 0.203511 0.0600562 Bak-R-E -0.125771 -0.220542 -0.0933526 -0.016474 -0.46435 0.0950166 0.043393 -0.187482 -0.412875 -0.261997 0.104749 -0.0515104 0.295636 -0.0308512 0.0560853 -0.366484 0.572319 Bap1-c-4-M-E 0.19993 -0.053287 -0.170174 0.0869649 0.154282 -0.549923 -0.142684 -0.489108 -1.1888 -0.162891 -0.241211 -1.69893 -0.0440964 0.0680608 0.107354 -1.47949 -1.22028 0.196386 -1.03172 0.0747924 -1.1122 -0.249802 0.0762031 -0.332935 -1.26614 0.119439 Bap1-c-4-M-V 0.148032 -0.218908 0.58744 -0.100938 -0.581848 -0.020231 0.121046 -0.82333 -0.671627 -1.19541 0.123647 -0.101098 0.331991 0.0427018 -0.18047 0.0688007 -0.888225 Bap1c-4-M-E Bax-R-V -0.0791507 0.223263 0.163882 -0.430925 0.242544 0.120837 -0.208155 0.445968 0.107019 -0.0686166 -0.687123 -0.0463634 -0.013612 0.51798 0.442513 -0.0785888 0.143454 -0.347391 -0.204923 0.226695 0.0082515 -0.440043 0.0807954 -0.193428 1.19549 0.289905 0.00451859 -0.209389 0.251891 -0.331411 0.498308 -0.0721368 0.497443 0.333371 0.0327193 -0.704146 0.160571 0.469642 0.481222 -0.0777228 -0.143734 0.349415 -0.0305783 Bcl-2-M-V -0.105921 -0.339531 -0.239504 -0.062814 -0.24046 0.972376 -0.199727 0.684663 0.10887 -0.482104 -0.354251 0.209786 -0.330516 -0.128115 0.097144 -0.095149 0.329148 -0.267837 0.400836 -0.163925 0.115319 -0.139351 -0.227724 0.00184293 0.507727 0.171289 -0.0293198 -0.124541 -0.0349321 0.320728 -0.116058 -0.126556 -0.186405 0.00150534 -0.333411 0.236497 0.0723989 -0.0331851 -0.222063 -0.0486884 0.223662 -0.181299 0.238357 Bcl-xL-R-C Bcl-xL-R-V 0.021938 -0.132094 -0.252938 0.143324 -0.05752 0.201139 -0.0451926 0.0711296 -0.304712 -0.201827 -0.29176 0.543763 0.235413 0.210965 0.15565 -0.242242 0.154388 -0.208143 -0.122165 2.11589 0.0749689 0.330064 -0.179017 1.07241 0.0839995 0.160547 0.18749 -0.106946 -0.269001 -0.0756326 0.362587 0.0397905 0.36907 -0.000663666 0.405773 -0.0184107 -0.158437 0.239622 0.0444076 0.0710329 0.108717 -0.0923116 0.0308287 Bcl2A1-R-V -0.171989 0.37359 -0.0313003 0.041611 0.0170471 -0.15825 0.29039 0.577627 0.126148 -0.070217 -0.300746 0.602463 -0.102504 0.270695 0.388214 0.137391 0.492407 0.0178819 0.262976 1.26165 0.41042 0.0554552 0.395752 0.169802 0.753226 0.0687705 0.111061 0.0966744 0.527467 -0.0242052 0.0387247 -0.431086 0.383016 0.170251 0.0412713 0.680712 -0.00586417 0.208844 -0.012996 0.044685 0.728258 0.669381 0.0355888 Beclin-G-C 0.219694 -0.310838 0.0357504 -0.101602 -0.0301198 -0.137073 -0.028595 -0.038857 -0.046607 -0.351939 -0.175587 0.103127 -0.198787 0.015068 0.154318 -0.262856 0.286519 0.0619068 -0.114438 0.131192 0.163994 -0.0589225 -0.0867734 -0.00550863 0.472028 0.167942 -0.216834 -0.00876237 0.12746 0.236668 0.0498779 -0.160851 0.11523 0.12176 0.0125551 0.705491 -0.200638 -0.0775026 0.0289184 -0.052623 -0.00953435 -0.477558 -0.0647113 Beclin-G-V Bid-R-C -0.174184 0.0495255 -0.0403945 0.0585888 0.381307 0.276391 0.300751 -0.00643157 -0.0319282 0.205048 -0.0313257 0.407209 0.111352 0.113458 0.25958 0.19578 0.642206 -0.125686 -0.129544 0.322639 0.350714 0.183403 -0.0383532 -0.164814 0.258658 0.0963105 0.0637343 0.0525668 0.260639 0.107 0.0181321 -0.019776 0.100148 0.194823 0.167655 0.224857 -0.0671288 0.152944 -0.043389 -0.0961504 0.179599 0.423174 0.0996208 Bim-R-V 0.056265 -0.372431 -0.459572 -0.0282562 0.0162778 1.10842 0.293996 0.341893 0.807613 0.300848 0.685234 -0.266323 -0.184702 0.238946 0.225832 0.204511 -0.098069 -0.282018 -0.0479821 -0.472707 0.18527 0.665764 0.349107 0.476842 0.91028 0.691284 0.106637 0.185694 -0.263446 -0.0368509 0.465403 -0.596843 -0.546416 -0.0562665 0.36759 -0.304752 0.501383 0.115688 -0.48873 0.290983 0.0194821 0.211808 0.359787 C-Raf-R-V 0.451409 -0.194375 0.0573292 -0.180397 0.0107893 -0.0115305 0.254973 -0.115006 -0.192173 0.255775 0.130309 -0.187918 0.435474 -0.326803 -0.200714 -0.0111076 0.121166 -0.00493218 -0.20339 -0.0314499 0.0463277 0.133095 -0.479454 0.0182919 -0.343369 -0.333815 -0.224783 0.330272 -0.557566 -0.200983 0.307909 -0.0904144 -0.714961 -0.649652 -0.0304581 -0.195026 0.144314 -0.297066 -0.295587 -0.28452 -0.060025 -0.535722 0.24026 C-Raf_pS338-R-C C-Raf_pS338-R-E 0.127697 -0.00147596 0.288017 0.268616 0.325003 0.100198 0.400421 0.348054 0.0785401 0.5735 -0.0377042 -0.0959971 -0.0131003 -0.0103093 0.182494 0.0281622 0.189015 C-Raf_pS338-R-V 0.0682584 -0.0817407 -0.147153 -0.117967 -0.0207309 0.260671 0.159097 0.158566 0.19884 0.0971352 0.0992919 0.357454 0.122191 -0.162623 -0.0200751 0.323942 0.170929 0.0753816 0.412291 -0.10102 0.087203 -0.117919 -0.0940767 -0.0702991 0.573946 0.0896108 CA9-M-E CD20-R-C -0.00211859 -0.135205 -0.0117817 0.0321537 -0.196932 -0.0886937 -0.119146 -0.149063 0.0431515 -0.311001 -0.157643 0.0915569 0.271825 -0.0777478 0.0573399 -0.0439242 -0.0926796 -0.101059 -0.152896 -0.0380701 0.0403023 -0.0123284 -0.141255 -0.109346 0.226824 -0.151465 0.00469056 -0.0650121 -0.229374 0.14659 -0.138752 -0.0796676 -0.1041 -0.288979 0.239861 0.050751 -0.15945 -0.225984 0.0873727 -0.0909783 0.0257128 -0.183824 0.0210935 CD26-R-V -0.259224 0.101709 -0.249278 -0.0419405 0.213342 -0.333576 -0.0903332 0.852278 0.00905821 -0.237702 -0.00033725 0.289675 -0.119384 -0.0077391 0.246691 -0.065114 0.497115 -0.132104 -0.000127161 0.352778 0.300362 -0.0109186 -0.19361 -0.0305259 -0.291502 0.119366 0.0115982 -0.118444 0.142266 0.353154 0.231114 -0.0229314 0.0262589 -0.0809669 -0.0569232 1.01632 0.279882 -0.0997729 0.0982724 0.0956933 0.309109 0.0479684 0.0884958 CD274-R-E CD31-M-V 0.0939925 -0.172442 -0.20365 0.0337947 -0.158797 -0.235168 -0.160616 0.438628 0.145793 -0.280656 -0.359793 1.05948 -0.122441 0.173357 0.267814 -0.0367343 0.19905 -0.21833 -0.199873 -0.214787 -0.239763 -0.0802972 0.174124 0.0852123 1.11121 0.162997 0.00875924 -0.0122148 0.0347527 0.260604 0.0725256 -0.0732119 0.30622 -0.0670369 0.00396344 0.111011 0.0415337 0.109133 0.00630042 -0.0562041 -0.407488 0.242464 0.145093 CD49b-M-V -0.0633029 0.969246 0.429033 0.088052 0.65366 0.295769 -0.29451 0.241576 0.382893 0.373667 -0.422366 0.996341 0.536253 0.117823 -0.13039 0.212503 -0.653133 -0.325428 0.230412 0.267332 -0.695456 1.20111 0.41394 0.0296821 1.22463 0.594635 0.555176 -0.248673 0.382013 -0.470454 -0.246737 0.761428 0.755545 0.671608 1.00213 -0.583211 -0.184274 0.985331 0.870932 0.0600317 -0.320209 -0.206373 0.0982813 CDK1-R-V 0.143271 0.211038 -0.256465 0.0747359 0.0552814 -0.162559 -0.0611717 0.144298 -0.0704184 -0.111078 0.0493307 -0.278541 -0.173311 -0.258549 -0.0186155 -0.0389895 0.586316 -0.365921 0.444604 0.716612 0.381412 -0.0553317 0.264518 0.321319 0.3296 0.14252 -0.181429 0.436658 -0.0343404 0.177895 -0.108183 0.0615945 0.152006 0.000663666 -0.0923251 0.203658 -0.111689 0.0605128 0.125674 -0.116774 0.00168497 0.469522 -0.0875126 CDK1_pY15-R-C 0.456348 0.208767 -0.0979352 -0.330462 -0.322054 -0.369694 -0.353299 0.308543 0.0639844 -0.454375 0.42732 0.18965 -0.294849 -0.104257 -0.122576 -0.340384 -0.111318 -0.277321 0.448452 -0.178705 -0.305235 -0.229307 0.458857 -0.204614 -0.180278 0.265471 -0.323947 0.616087 0.179912 -0.0499507 -0.308653 0.0632613 -0.00706151 0.248744 -0.351395 -0.0831087 -0.155306 0.216415 0.486321 0.0820876 -0.302074 -0.152132 -0.160352 CK5-M-E COG3-R-V 0.218289 -0.100921 0.0925823 -0.0522914 -0.316628 -0.220803 -0.205599 -0.521413 -0.0656228 -0.208758 -0.295483 -0.68286 0.094636 -0.699543 -0.53931 -0.322814 -0.476537 0.0986303 -0.428159 -0.123066 -0.45844 -0.241414 -0.0924421 -0.0951266 -1.2067 -0.482332 -0.6344 -0.712841 -1.371 -0.160788 0.102093 0.0453385 -1.16864 -1.17762 0.160924 -0.636662 0.242282 -0.961326 -0.154763 -0.270699 -0.323942 -1.77621 0.0138243 CTLA4-M-E Caspase-3-R-C 0.0067887 0.0393542 -0.0729975 0.133937 -0.050175 -0.00268753 0.129483 0.115451 0.0929402 -0.325299 0.0325465 0.386999 0.056299 -0.0134584 0.217582 0.145967 -0.0192267 0.00560157 0.0607315 0.285873 -0.889241 0.434642 0.248349 -0.240631 0.265724 -0.0260142 0.117552 -0.0120374 0.733886 -0.222507 0.000674229 -0.00778086 0.335784 -0.112427 0.063088 -0.216799 0.10321 -0.00430233 0.0621481 -0.0468321 -0.529514 0.451108 -0.00904586 Caspase-3-R-E Caspase-7_cleavedD198-R-C 0.527109 1.09535 -0.377712 0.850402 0.138414 1.22351 1.12325 1.33806 1.38783 0.328511 0.288692 -0.149009 -0.542646 0.492794 2.70721 2.69828 0.0931366 -0.292446 1.11269 0.767705 0.492892 1.26831 0.672004 1.98422 -0.0731617 2.51282 1.28427 1.60046 2.37977 -0.106457 0.164822 1.56769 2.36276 0.71683 0.111234 -0.333844 2.51434 1.87651 1.90261 2.11255 2.01752 1.36529 0.767195 Caspase-8-M-E -0.136178 0.0778573 0.422298 -0.167393 -0.127106 -0.390006 0.218495 -0.17096 0.156044 -0.0651084 -0.0795391 0.438238 0.000871996 0.383561 0.228691 0.0751131 -0.480701 -0.0521417 -0.116119 -0.248001 -0.173828 0.170622 -0.339115 -0.0127416 1.37622 0.581396 -0.122608 0.480834 0.436406 -0.0262467 -0.214689 0.20257 0.591471 0.165446 -0.312452 -0.01107 0.445695 0.336204 0.0933175 0.211076 0.103313 0.273747 0.0679857 Caspase-9-R-C Caspase-9-R-E Caveolin-1-R-V -0.297916 0.383793 -0.728574 -1.33073 1.07579 -0.226565 -0.186914 0.373291 0.527751 0.0563484 0.0453432 -1.01272 0.193269 1.56596 -0.336839 0.30917 2.05552 0.0237425 2.05614 -1.7037 0.757961 -0.697344 1.87193 0.689193 1.35709 0.597695 -0.0172532 0.875615 -0.789539 1.08019 -1.66816 -0.624184 -0.485834 0.00704643 -0.876619 2.7063 -1.28666 0.890295 0.554016 1.56027 0.677465 1.11928 0.158752 Chk1-M-C 0.248782 0.287306 -0.0838406 0.605884 0.0400319 -0.292929 0.145518 -0.583604 -0.0788688 -0.103656 0.355598 -0.378817 -0.50785 0.133725 0.255444 -0.856332 -0.292239 0.246974 -0.487314 -0.159626 -0.150376 -0.00208947 0.053785 -0.134114 -0.335189 -0.197851 Chk1-R-C Chk1-R-E 0.0804981 0.229291 0.222102 0.311395 0.533103 -0.0129959 0.038456 1.4666 0.910163 0.41683 -0.106277 0.303823 0.831627 0.13615 0.247484 -0.056431 1.58544 Chk1-R-V Chk1_pS296-R-V -0.106439 0.0677421 0.0155946 0.0501237 0.0612766 -0.119726 0.109099 0.331018 0.125212 -0.119427 -0.220433 0.517221 0.0166486 0.209942 0.234098 0.0674333 0.183833 -0.0535738 0.155266 0.270489 0.274877 0.162599 0.109645 0.147222 0.438617 0.0812464 0.172032 0.0450675 0.33671 -0.194276 -0.136554 -0.0631123 0.455339 -0.0763228 -0.064299 0.200296 -0.0705641 0.1831 -0.021038 0.0875172 0.355092 0.321652 -0.00690109 Chk1_pS345-R-C 0.0641795 -0.108872 0.139928 0.433478 -0.266543 -0.185564 -0.12847 -0.127476 0.0320627 0.404205 0.0962486 -0.194293 -0.214455 -0.249738 -0.23942 -0.0983249 -0.0351956 0.288972 -0.14697 -0.194204 -0.638533 0.0148008 -0.230048 -0.0265771 -0.226995 -0.0725682 -0.123361 -0.0029843 -0.231975 0.0200875 -0.0881582 0.0186803 -0.348748 -0.239203 -0.145802 -0.08126 -0.0443578 -0.191257 0.10921 -0.299854 -0.174881 -0.173741 -0.239921 Chk2-M-C Chk2-M-E -0.0228456 -0.144825 0.0228522 -0.0925518 0.0807147 -0.334663 -0.183052 -0.825233 0.0495365 -0.0461019 0.0597346 0.382647 0.00492054 -0.474972 -0.0912472 0.30614 0.100232 -0.185289 -0.529471 -0.300336 0.331053 -0.13273 -0.0867437 -0.698792 0.0126374 -0.046604 Chk2-M-V 0.18368 0.13452 0.666346 -0.285307 0.0834833 -0.268619 0.170128 -0.455798 0.338197 -0.776513 -0.196644 -0.280319 -0.22258 0.869519 0.364885 0.478447 0.552268 Chk2_pT68-R-C -0.0754412 0.0140294 -0.0219913 0.158904 -0.0632911 0.320693 0.173912 -0.376561 0.107927 0.0556684 0.0156744 0.323407 0.0495964 -0.068966 -0.12321 0.15354 0.270417 -0.0344736 0.278767 -0.181988 0.0214566 -0.100219 -0.0734616 -0.269543 0.61071 0.0423348 Chk2_pT68-R-E -0.130567 -0.179608 0.117364 0.163918 0.129217 -0.0213736 0.649559 0.208719 -0.209337 0.386838 0.0107833 -0.151509 0.220223 0.277902 0.370121 0.0511076 0.489304 Chromogranin-A-N-term-R-E Claudin-7-R-V -0.235031 0.00204792 1.5124 0.157937 0.0226853 0.233014 -1.20451 -0.131836 -0.0963231 0.70108 0.518383 0.689344 0.82051 -1.30069 0.61354 1.36577 -1.73636 -0.865617 -0.586906 0.419808 -1.97007 0.542883 0.991813 0.981727 2.12489 -0.443818 0.721069 -0.952721 -0.799096 -0.738447 0.561205 -0.644358 0.00424393 -0.373998 0.77016 -1.57603 1.31144 -0.370418 1.86428 0.0687588 -1.81092 -0.299611 -1.31001 Collagen_VI-R-V -0.641372 -0.281888 -0.595085 -0.435475 -0.115507 -0.543833 -0.103763 0.799857 -0.259874 -0.580254 0.862028 0.539558 -0.351851 0.0398069 0.144346 -0.0891272 2.16956 -0.297306 0.0265653 0.158092 0.81788 -0.483965 0.31697 0.321428 1.17082 0.0135642 -0.163219 0.136224 0.310935 0.584112 -0.158725 -0.255288 0.435678 0.191961 -0.0469183 0.835262 -0.393681 0.0600922 0.0278015 -0.187718 0.440639 0.697099 -0.116142 Complex-II_subunit30-M-V Cyclin_B1-R-V 0.831833 0.872546 0.0600783 -0.168073 0.396157 1.34923 1.39902 0.856141 0.643862 1.03242 1.18733 -0.696407 0.264576 1.32119 -0.436284 0.693668 -0.9498 0.0284004 1.46346 0.199413 -0.515073 0.481427 0.460622 1.33994 -0.659714 1.28985 0.29131 1.55764 0.226234 -0.541731 0.271425 0.0948821 0.478002 0.139187 -0.181398 -1.15526 0.407965 0.37541 0.31664 0.833026 -0.0158661 0.958571 0.400272 Cyclin_D1-R-V -0.00874358 -0.0298797 -0.105497 -0.122102 0.215019 0.142224 0.269422 0.0971998 -0.00146926 -0.0456835 0.109421 0.0734972 -0.372104 0.141756 0.37733 -0.285689 0.39204 -0.0825742 0.0523079 0.0811191 0.362926 0.157736 -0.000730761 -0.159839 0.333423 0.259331 0.497366 -0.0888143 0.351923 0.239827 -0.0539489 0.0609212 0.676137 0.162913 -0.344988 0.583588 -0.231681 0.166738 0.00288313 -0.128272 0.283385 0.215541 -0.139602 Cyclin_E1-M-V 0.851754 0.340636 -0.390692 0.226462 0.370051 0.269955 -0.227665 1.19894 0.297845 -0.0978848 -0.00516519 -0.00773815 -0.323849 1.05329 -0.356737 -0.345806 -0.890429 -0.173082 0.853952 -0.30025 -0.750471 0.496459 -0.553225 0.16071 -1.01245 0.111618 -0.310804 -0.0753804 -0.010072 0.210877 0.267791 -0.184621 -0.0748591 0.345561 0.390665 -0.86834 0.36452 0.0806743 -0.163501 0.137431 -0.566232 0.0633614 -0.182894 Cyclin_E2-R-C 0.022443 -0.147896 -0.13426 -0.0182296 0.112077 0.0886594 0.114194 -0.376017 -0.0136581 0.177066 0.101966 -0.0657894 0.249062 0.22232 -0.148958 -0.00785841 -0.513081 0.131162 0.1594 -0.303693 -0.334813 0.00610657 -0.147906 0.459527 0.176929 -0.154926 -0.0473616 0.0177693 -0.341668 -0.151036 -0.0827868 -0.0962932 -0.157908 -0.271791 0.280042 -0.301386 -0.00011762 -0.172724 0.0219486 0.088625 -0.210096 -0.409079 -0.078642 DIRAS3-M-C DIRAS3-M-E -0.0441396 -0.272603 -0.00361188 -0.152106 -0.168157 -0.0278445 -0.216408 0.0742733 0.030011 -0.38433 -0.232601 0.61786 0.0227364 -0.0683193 0.0450134 -0.0798122 0.263553 0.000609894 0.00951856 0.267539 -0.000390059 0.137264 0.0644963 -0.0626451 -0.00321166 -0.19568 -0.051323 0.163889 0.0956281 0.366798 0.0968963 -0.044274 -0.0374627 0.116951 0.0998733 0.24944 0.0384079 -0.00898864 -0.103394 -0.0510382 -0.523036 0.210763 0.111157 DJ-1-R-C DJ-1-R-E -0.389133 0.0547672 0.00948705 -0.180864 -0.0793891 0.155264 0.067118 0.306671 -0.0424365 -0.171416 -0.0832861 0.365854 -0.0433106 -0.177355 -0.207454 0.421659 0.0163051 -0.174583 0.18439 -0.172342 0.0661305 -0.179324 -0.161282 0.118133 0.604997 0.236999 DJ-1-R-V -0.355602 0.0885079 0.859874 -0.168744 0.328816 -0.386009 -0.171752 0.144418 0.0473206 0.665422 -0.376423 -0.117898 -0.116244 -0.097221 -0.10515 -0.069898 -0.514324 DUSP4-R-V 0.589541 -0.611711 0.695316 -0.412878 -0.318073 -0.141698 -0.409087 0.698104 -0.337827 -0.52518 -0.00638112 0.165408 0.733786 0.938033 -0.227414 0.157567 -0.277358 -0.274638 1.01439 -0.477182 -0.516939 -0.138599 -0.277482 -0.1211 -1.31145 1.14024 -0.136143 0.476772 1.51113 0.210877 0.049874 1.11166 0.659502 -0.191017 0.00415442 -0.564268 0.506174 0.47975 -0.662538 0.0646655 -0.737147 0.399477 -0.154647 Dvl3-R-V -0.195059 0.41569 0.0361044 0.466577 0.587757 1.40293 0.839499 -0.614894 0.151081 1.26523 0.95503 -0.974224 0.593935 -0.258549 0.152978 0.232808 -0.517782 0.915777 0.90935 0.0536626 -0.220605 0.411843 -0.171558 -0.0696272 -0.147898 -0.0654598 0.109435 0.125586 -0.569057 -0.187043 0.149567 0.431092 -0.321294 -0.0219709 0.0315869 -0.553424 -0.22688 -0.392194 -0.0225282 0.0980195 0.122044 -0.110075 0.197716 E-Cadherin-R-V 0.348257 0.169104 0.996443 -0.320658 -0.798398 1.27562 -0.149685 -0.550631 -0.160497 0.777022 0.0544038 -1.69587 0.368392 -1.51055 -1.33659 -0.114025 -2.73302 0.818283 -0.370427 0.185705 -2.14483 -0.0581465 0.654946 0.589885 1.12518 -2.18557 0.361216 -1.778 -3.42079 -0.276765 0.0654321 -0.2098 -2.25275 -1.85355 0.65725 -3.57584 0.165073 -2.09347 1.21988 -0.429219 -2.51139 -3.18483 -1.3555 E2F1-M-C EGFR-R-C 0.072104 -0.350823 1.36116 1.18897 0.657893 1.24535 0.187239 -0.0516575 0.0125738 -0.270248 0.978968 2.99011 0.632038 0.301711 -0.0594531 0.15545 -0.59672 EGFR-R-V -0.123558 0.446326 0.0252396 0.225474 0.816537 0.308125 0.190056 0.0567966 0.119149 0.41227 0.189963 -0.497873 -0.295031 0.290332 0.295004 -0.690691 -0.362746 -0.364434 -0.0211048 -0.0936254 -0.205662 0.619451 0.875401 0.315701 -0.564411 -0.122145 EGFR_pY1068-R-C 0.169638 0.575605 0.274696 0.628825 -0.848087 -0.576995 0.46246 0.045883 -0.299302 1.64489 0.173408 0.0133158 -0.0962741 -0.851131 -0.172001 -0.380103 -0.241065 1.0473 3.67569 0.584159 -0.830874 0.157482 2.10779 -0.067366 0.585929 0.0210024 0.252648 0.302562 -0.695093 0.449914 0.0476379 -0.0410533 -0.629893 -0.350807 -0.135778 -0.172937 0.202117 -0.525843 1.59705 -0.0235734 -0.420808 -0.170037 -0.125267 EGFR_pY1068-R-V EGFR_pY1173-R-C EGFR_pY1173-R-V -0.102325 -0.053036 -0.0918994 0.0547752 0.0422026 0.00384656 0.0331543 -0.00626885 0.0257819 0.0670601 -0.0649042 0.126364 0.0381991 -0.025061 0.0479202 0.121027 -0.0791294 0.103923 1.2446 0.0973499 0.181458 0.000748559 0.386734 -0.0972399 0.288384 0.0326477 0.0720636 -0.00203117 0.0484302 0.0780017 0.015386 -0.0300202 0.0635127 0.0684822 0.161799 0.121776 -0.0429924 -0.0263009 0.126924 -0.0208024 -0.0088118 0.242328 -0.0604364 ENY2-M-V 0.0191127 -0.166377 0.121161 0.254506 0.0149698 -0.101966 0.264782 -0.36244 0.420003 -1.09243 0.118302 0.0151095 -0.0105574 -0.243926 0.0629201 -0.374217 1.16362 EPPK1-M-C -0.0736253 0.0764699 -0.0345227 -1.87443 -1.73553 1.49756 -0.700045 -2.17408 -3.12098 -0.30013 1.79706 -0.785789 2.4819 0.391716 -0.439144 1.52115 -2.74997 EPPK1-M-E -0.127932 2.13794 1.33716 0.75684 1.28997 -0.530411 0.685341 -1.47763 -2.8011 1.21398 0.0244361 -0.989019 0.173285 0.962586 0.276253 -1.78856 -1.26622 -0.240632 -0.0956093 -0.260508 -0.931961 0.62393 0.0659003 -0.116165 -1.39029 -0.98186 ER-alpha-R-V 0.209443 -0.363497 -0.170418 0.123696 1.02584 -0.0805412 -0.0621906 0.161982 -0.113423 -0.345311 -0.25057 0.277731 -0.282667 -0.230938 0.188695 -0.163314 0.456918 -0.115345 -0.234108 0.185078 0.260531 -0.187452 -0.0995445 -0.0931734 0.348416 -0.298689 0.0580889 -0.0464526 -0.102861 0.526476 0.0721806 -0.167507 -0.0572112 0.1628 -0.192492 0.167389 0.0612591 -0.117246 -0.336553 0.473647 0.188817 -0.0476428 0.698332 ER-alpha_pS118-R-V 0.0401885 -0.109566 -0.00969234 0.116053 -0.132148 0.0514905 0.0538177 -0.253159 -0.0367289 0.0062206 0.000656414 -0.0769286 0.190823 -0.122145 -0.21576 -0.0473336 -0.243226 0.0110551 -0.217536 -0.0903794 -0.369704 0.0709398 -0.097404 -0.333259 0.567291 -0.167106 0.0122899 -0.0166906 -0.174278 -0.136256 -0.0167822 -0.0783332 -0.0321057 -0.335282 0.240705 -0.163526 -0.129823 -0.159113 0.048392 -0.164902 -0.0542988 -0.210763 -0.121001 ERCC1-M-E 0.116169 0.103262 0.0222635 -0.0241472 -0.19854 -0.170411 -0.016112 0.535671 0.179386 0.0975011 -0.155499 -0.221466 0.0179314 0.249393 -0.254701 -0.0845334 0.675034 ERCC1-M-V 0.264091 0.190605 -0.0717739 0.151831 0.123089 -0.0591902 0.0872172 -0.0347223 -0.504407 -0.122317 -0.0483541 -0.555647 -0.0407521 0.115517 0.11409 -0.919412 -0.662362 0.225811 -0.395725 0.0727058 -0.467549 -0.0345592 0.263587 0.277163 -0.680559 -9.24355e-05 ERCC5-R-C 0.020822 -0.0837848 0.348912 0.230537 -0.388877 0.0803622 -0.281506 0.0167867 -0.00681936 0.157623 -0.0602962 -0.0847616 0.0224933 0.293377 -0.223935 -0.228431 -0.345277 -0.204569 -0.31841 -0.443972 -1.4395 -0.354403 0.237829 -0.0521242 0.486531 -0.00352096 -0.271526 -0.113024 0.374134 -0.118122 0.0114225 -0.0359516 0.723763 0.106695 -0.335261 0.248592 0.253806 0.298731 0.149833 0.151287 -0.398462 -0.0124159 -0.175797 ERK2-R-C ERK2-R-E -0.365692 -0.0548418 -0.208137 -0.250963 -0.0510888 -0.241152 0.176628 -0.950957 -0.0393199 -0.0308977 -0.110036 -0.124503 -0.0661503 0.0542063 0.117375 0.130766 -0.173314 -0.389314 -0.138967 -0.317262 0.143762 0.0778256 -0.282119 0.0372696 -1.04096 -0.0504427 0.120775 0.0495657 0.0787145 0.0588229 -0.004752 -0.0240084 0.292967 0.247139 -0.0786955 0.0413124 0.0329548 0.363526 0.000336684 0.021649 0.256957 0.411585 0.0652514 ETS-1-R-V -0.00146342 0.0127948 -0.152855 0.15541 -0.0149751 -0.0259022 -0.111021 -0.249686 0.0463528 -0.0827397 -0.58073 -0.143979 0.169698 -0.094621 0.107794 -0.0627245 -0.329928 -0.521551 -0.0765413 0.261925 0.142662 0.45655 -0.724256 0.0715674 -0.296338 -0.0751622 0.117975 -0.0627166 -0.0760263 0.0314715 0.0811856 0.229683 0.155711 -0.13717 -0.0108302 0.230837 0.00442607 -0.0151587 -0.158627 0.14355 0.284476 -0.0567898 -0.0845434 EZH2-R-C FASN-R-V 0.700238 0.26669 0.198455 -0.174347 0.000292654 -0.0838173 0.0202397 -0.556805 -0.414096 0.10802 0.115669 -1.70701 0.552987 -0.326741 -0.504063 0.348155 -1.65157 1.0348 -0.842854 0.1332 -0.599227 -0.194015 -0.579616 -1.42389 -1.88761 -0.20017 -0.565818 -0.348204 0.858501 0.605281 0.0673863 -0.464126 0.385239 -0.193126 0.190188 -1.72477 -0.119634 -0.0623477 0.557395 -0.632548 -0.917034 -0.226056 -0.55988 FOXO3a-R-C -0.197264 -0.328508 0.0422467 0.0120255 -0.0392151 0.166817 0.0966426 0.0724668 0.0866945 -0.121062 0.462777 0.0375885 -0.211418 -0.114793 0.074974 -0.166136 0.165328 0.524996 0.14596 0.258843 -0.23824 0.0402651 0.450369 0.0017899 0.558264 -0.180812 0.252072 0.0283182 0.0701682 0.148012 -0.0846099 -0.0727009 0.158827 0.00516358 -0.12319 0.368576 -0.0690508 0.029755 -0.0355212 -0.0235647 0.223337 0.397998 -0.0209876 FOXO3a_pS318_S321-R-C 0.0384556 0.0900525 -0.219017 0.0849652 -0.332449 -0.328463 -0.347557 0.123415 -0.215336 -0.377321 -0.277366 0.0938772 -0.436466 -0.142626 -0.0219728 -0.353906 0.296271 0.00475601 -0.0800215 0.160499 0.146169 -0.267909 -0.0509332 -0.064061 -0.33577 0.0894209 -0.0247537 0.0206804 -0.294291 0.314359 -0.188943 -0.087547 -0.298589 0.129046 -0.275057 0.56965 0.0583696 -0.0699486 -0.142038 -0.179188 -0.112651 0.000254029 -0.0451905 Fibronectin-R-C Fibronectin-R-V -0.984581 0.758828 -1.41724 -1.17804 0.794265 -0.286827 0.357837 0.325287 0.390744 -0.275866 -0.39697 1.361 -0.0631697 0.127481 0.890428 -0.220925 0.562582 0.0977798 -0.193925 -0.950446 0.0935549 -0.213367 0.583497 -0.39497 1.37928 0.1483 0.372659 0.34665 1.06722 -0.0480732 0.26937 0.244357 0.936222 0.685751 0.394042 0.555254 -0.250359 0.730442 0.723394 -0.555837 0.0320713 1.2071 0.368126 FoxM1-R-V 0.2936 0.680901 -0.018567 -0.218887 -0.344326 2.21851 0.112185 -0.0811396 0.165666 -0.00949925 0.534193 -0.196285 0.216473 -0.412535 -0.232741 -0.133267 -0.333219 -0.0102898 -0.0193286 -0.22974 -0.111822 0.126698 0.117955 0.360883 0.0208083 -0.217182 -0.0331513 0.352057 -0.151971 -0.0817932 0.113445 0.0561366 -0.473304 -0.180021 -0.0136457 -0.100883 0.13661 -0.28624 -0.226769 0.310724 0.0647664 -0.0319902 -0.0136521 G6PD-M-V -0.356022 0.146021 -0.0194867 2.44749 1.95667 0.182789 -0.0439229 0.394545 0.119169 -0.501605 -0.489823 0.670633 2.05261 0.34984 1.31785 0.800038 0.228575 -0.125959 0.0613708 2.49162 0.50844 0.444748 0.420744 0.383404 -0.0666145 0.356663 0.350737 -0.0866288 0.370997 -0.118246 0.0414948 -0.1865 0.87457 0.0480469 -0.180823 0.0994475 0.160569 0.752361 -0.459278 0.932173 0.179129 0.181689 0.136452 GAB2-R-V 0.718674 -0.0606884 -0.42907 -0.000735815 0.0866721 -0.00529416 0.298435 0.1926 -0.00502042 0.342973 0.00033725 -0.529483 -0.204078 -0.56547 -0.110063 -0.410769 -0.331661 0.140305 -0.316654 -0.686491 0.282421 0.523827 -0.653155 -0.343343 -0.331907 -0.742634 -0.104585 -0.397573 -1.15206 0.123533 0.324566 -0.110541 -1.86669 -0.951815 1.03107 0.015288 0.336274 -0.340305 -0.410303 -0.446503 0.446613 -1.41111 0.115026 GAPDH-M-C -0.624686 0.729531 1.12208 0.189353 0.623883 1.53944 1.15785 -0.0029089 0.101008 1.01794 -0.352688 -0.58503 0.717046 1.1461 -0.0472849 0.35525 -0.971766 -0.140222 0.412822 0.0382195 -0.383758 0.0502881 -0.191981 -0.0728877 -1.80544 0.0510438 0.226553 0.411855 1.47689 -0.807291 0.372503 0.127359 1.17305 -0.00551725 -0.477169 -0.110471 -0.406504 1.35746 0.213925 0.502656 -0.0941942 0.0936791 -0.275273 GATA3-M-V 0.86403 -0.716928 0.33514 -0.574512 -0.450722 -0.238762 -1.20707 0.460845 -1.07509 -1.21701 -0.939571 -0.391739 0.553129 -0.935669 -0.885389 -0.648795 -1.0825 -0.968947 -0.882958 -0.974557 -0.922073 -1.03691 -0.772381 -0.549053 -1.09614 -1.31193 -0.826461 -1.12867 -1.3309 0.0677009 -0.0302873 -0.391625 -1.16298 -0.868343 -0.502182 -0.886741 -0.470228 -0.654184 0.325573 -0.948169 -1.35869 -1.42222 -0.34113 GATA6-R-E -0.237749 -0.000292653 0.259129 -0.123607 0.161507 -0.399595 0.0130848 0.341081 -0.119276 0.71486 -0.0799659 0.0893023 0.218075 0.0366019 0.199736 -0.198167 0.132203 GCN5L2-R-V -0.226634 -0.0759456 0.402696 0.465685 0.0322673 1.12344 0.447186 -0.556631 0.952309 -0.809023 0.841797 0.113555 -0.0566663 -0.0387538 -0.877805 -0.582854 -0.947587 GSK3-alpha-beta-M-V 0.066824 0.017161 -0.0358936 -0.0120875 0.125539 0.268934 0.229222 -0.149503 0.147467 0.363167 -0.0779123 -0.247489 -0.204605 0.59172 -0.00253396 0.0501827 -0.140562 -0.0779534 0.531285 -0.189515 0.0262109 -0.115575 -0.50303 -0.0959979 -1.11781 0.320665 -0.0108178 -0.0159467 0.102367 -0.260896 -0.134796 0.0573503 0.46183 0.262387 0.266713 -0.0342551 -0.255522 0.193527 0.141742 0.163805 -0.144251 0.186013 0.0464028 GSK3-alpha-beta_pS21_S9-R-V 0.240684 0.398984 0.384777 0.119824 -0.311315 -1.92721 -0.512701 -0.314218 -0.0432682 0.848539 -0.264189 -0.335655 -1.0995 -0.140314 -0.855568 -0.866967 0.254072 0.0963751 0.146283 -1.56305 -0.197718 -0.680736 0.232185 -0.0123608 -1.12479 0.290989 -0.390858 0.0416522 0.150809 0.220028 -0.469806 0.414574 0.220782 0.725186 -0.449162 0.196179 0.266474 0.454236 0.746412 -0.469117 -0.16265 -0.75541 -0.260659 GSK3_pS9-R-V 0.0814365 0.180358 0.222377 0.73231 -0.324447 -1.44234 -0.291543 -0.645039 -0.332744 1.33324 -0.197354 -0.139917 -0.876758 -0.104316 -1.08351 -1.14711 -0.0379119 0.13021 0.15735 -1.18488 -0.650646 -0.521711 0.203985 -0.124865 -0.638564 -0.112205 -1.01378 0.0673088 -0.154518 0.178132 -0.505606 0.530939 0.374393 0.762716 -0.101111 0.0270117 0.0622299 0.270824 0.659825 -0.369202 -0.00130638 -1.28103 -0.382215 GYG-Glycogenin1-M-E GYS-R-V GYS_pS641-R-V Gab2-R-V HER2-M-V 0.371116 -0.427946 0.873781 -0.0131217 -0.630341 -0.110505 -0.473119 -1.24518 -0.783661 0.173912 -0.181027 -1.7388 0.585956 -1.58162 -1.01176 -0.424446 -1.45585 0.778348 -1.55421 -1.02113 -0.839862 -0.165763 -1.14752 -0.81106 -1.10711 -1.25293 -0.704415 -0.946959 -1.72286 0.257233 0.391233 -0.212609 -1.4527 -1.20455 0.315274 -1.06058 -0.0021591 -1.22925 0.0475445 -0.662776 -1.31343 -1.69862 -0.532701 HER2_pY1248-R-C 0.00838098 -0.00493441 0.366335 -0.00950854 -0.554347 -0.495578 -0.155324 -0.361911 -0.199927 0.568041 -0.298386 -0.324226 0.295933 -0.854054 0.032728 -0.261661 -0.286006 0.316009 1.42758 -0.0103041 0.0247143 -0.225665 0.734408 -0.606085 0.0785341 -0.382135 -0.147787 -0.368907 -0.11935 -0.097961 0.0264155 -0.298582 -0.206183 -0.458712 0.207534 -0.0692455 0.00725363 -0.277476 0.25044 -0.359131 -0.254582 -0.249849 -0.230394 HER2_pY1248-R-V HER3-M-C HER3-R-V 0.230569 -0.270851 0.537684 -0.092062 -0.638224 0.440902 -0.583156 -0.526446 1.00257 0.196327 -0.287617 2.86922 0.248977 -1.08081 -0.0154825 -0.0203477 -0.066708 0.392416 -0.783614 -0.0424921 0.215422 0.0543247 -0.102216 -0.47233 -0.237327 -0.458075 -0.153244 -0.720502 -0.588761 -0.0979205 0.3865 -0.48644 -0.506968 -0.75346 0.271386 -0.61387 0.387049 -0.652926 -0.227081 -0.482051 -0.345493 -0.156515 -0.260093 HER3_pY1289-R-C -0.151722 0.0527501 -0.0193418 0.0956344 0.117542 0.194957 0.28978 0.121696 -0.0999002 0.484192 0.0667617 0.136283 0.228161 0.158124 -0.00213869 0.00454931 0.313944 0.0980442 0.107638 0.155088 0.0264649 0.18197 0.331373 -0.103397 0.668411 -0.081035 0.121088 -0.0315481 0.0631812 -0.1209 -0.0120111 0.119838 0.230099 -0.0281619 -0.21975 0.423852 0.00588883 0.13022 0.260592 -0.0614856 0.0627009 0.0273269 0.108193 HER3_pY1289-R-V HIF-1_alpha-M-E HSP70-R-C -0.0595968 -0.426754 -0.366726 -0.352713 0.571547 -0.498476 1.56712 0.782379 0.480213 0.112778 -0.396827 0.965135 -0.200759 -0.730538 1.21662 0.139373 1.80063 -0.730876 -0.24609 0.851831 0.966593 0.280871 0.809252 0.919033 0.0175579 0.516626 0.848665 0.0498026 0.2179 0.155956 -0.0222515 0.106383 0.0912871 0.719374 -0.0187561 1.03555 -0.149435 -0.336444 -0.548737 -0.415213 0.703657 0.742839 0.394363 Heregulin-R-V 0.0583452 0.00318362 -0.210349 0.0584659 0.0883837 0.106332 -0.0988993 0.116596 0.488204 -0.289382 -0.154789 1.37569 0.305512 -0.0247818 0.848114 0.353104 0.197253 0.141667 0.675586 0.552273 0.431447 0.357061 0.477205 -0.101619 0.63735 0.449308 0.218076 -0.00918478 0.0157927 -0.148151 -0.170727 -0.0703062 -0.123665 -0.220774 0.340422 0.244911 -0.151363 -0.0357899 -0.120642 0.118441 0.262679 0.395187 0.0297347 IGF1R_pY1135_Y1136-R-V -0.0795888 -0.0340521 -0.0608451 -0.221573 -0.116725 -0.115941 0.0809032 0.198554 0.111732 -0.247048 -0.146206 0.463653 -0.0285032 0.0116791 0.0825756 -0.0765184 0.442619 0.0313477 0.11676 0.304079 -0.0107302 0.0363492 0.121986 0.00112057 0.213142 0.0665687 -0.117134 -0.0577424 0.0402408 0.356919 -0.19319 -0.143826 0.0420045 0.0213032 0.0130415 0.502646 -0.0808983 0.057 -0.0403535 -0.146896 -0.309273 0.196629 0.0785387 IGFBP2-R-V -0.410058 -0.272528 0.31088 0.822503 -0.0102889 0.919629 -0.60731 -0.0572828 -0.118378 -0.367501 0.203615 1.03355 -0.487836 -0.492347 -0.442129 -0.419683 1.53944 -0.487188 -0.726937 -0.57478 0.284672 -0.114545 -0.237283 -0.411024 3.22904 1.56019 -0.064335 -0.341837 -0.310005 0.203243 -0.208003 -0.264656 -0.566193 1.15957 0.767349 0.0986557 -0.460999 -0.379778 0.0567978 -0.626795 -0.31575 0.45156 -0.265953 INPP4B-G-C INPP4B-G-E 0.000828488 -0.369462 -0.748708 -1.1781 -1.21503 -1.08162 -1.32729 -0.345916 -0.365318 -0.842879 0.367836 -0.834431 -0.716442 -0.268991 -0.213256 0.00184293 -1.22681 INPP4B-R-V 0.424676 -0.0706775 -0.0123654 -0.29452 0.256351 -0.240607 0.0909488 -0.504039 -0.417641 -0.378056 -0.396353 -0.580736 0.0665993 0.992764 0.265598 -0.401782 -0.307187 -0.290323 -0.100331 -0.369687 -0.063427 0.131733 -0.105153 -0.307368 -0.0681437 -0.0405699 IRF-1-R-C -0.128956 0.173641 0.0642497 0.497873 -0.275512 -0.447062 0.955263 -0.240186 0.120879 0.317504 -0.349949 0.223116 0.0842336 -0.0542201 -0.0596009 0.243767 -0.0350736 0.286583 0.0754644 1.75685 -0.164962 0.186898 0.64189 0.281107 0.164701 -0.142855 0.197923 -0.132405 0.232523 -0.0371751 -0.01421 0.187387 0.313986 -0.23767 -0.134601 0.261303 0.444683 -0.0467769 0.289281 0.0540802 0.230588 0.299646 -0.099303 IRS1-R-V -0.0382817 0.435788 0.43637 -0.130636 0.0454413 -0.162696 0.178655 -0.344001 0.089719 0.161626 0.25713 0.00773815 0.763573 -0.372817 -0.0141747 -0.0533866 -0.11229 0.486968 -0.42082 0.557179 0.02856 0.343003 0.0125845 0.00184293 0.138349 -0.234134 -0.0547049 -0.0290363 -0.200715 0.0248353 -0.0417656 0.097259 -0.194557 -0.15471 0.100209 -0.000694543 -0.139129 -0.281996 0.417973 0.147896 -0.0418825 -0.0601961 -0.107688 JAB1-M-C 0.0098913 -0.265539 0.114295 -0.0525602 -0.15353 0.0228649 -0.332895 0.298077 0.0871969 -0.3893 -0.19409 0.458704 0.103825 0.183092 0.0211229 0.0831789 0.115329 0.025305 0.0563539 0.233767 -0.0661947 0.19886 0.116906 -0.250376 -0.38864 -0.0992099 0.0818428 0.188791 -0.0798862 0.458577 0.182063 0.0206547 0.0542952 -0.0195865 0.0491472 -0.157432 0.0318389 0.113897 -0.106736 0.0226153 -0.363592 0.140077 0.192031 JNK2-R-C -0.18144 0.176556 0.218522 0.107585 0.51527 0.0296152 0.0277069 -0.462595 -0.215375 0.233127 0.156045 -0.259617 0.253214 0.310315 0.0306647 -0.0172329 0.266168 -0.414706 -0.1246 -0.154372 0.138478 0.265864 -0.81569 0.0883627 -0.859921 -0.378324 0.00153805 0.0125378 -0.234972 0.173605 0.217922 0.182185 -0.655078 -0.130749 -0.142934 0.190449 0.0306757 0.44689 0.0755871 0.118441 0.373579 -0.337766 -0.0719844 JNK_pT183_pY185-R-C JNK_pT183_pY185-R-V -0.159513 -0.148941 -0.193211 -0.107404 -0.272347 -0.220214 -0.171553 0.123057 -0.0407684 -0.173812 -0.112006 0.411501 -0.146117 -0.260981 -0.020935 -0.0841555 0.513654 -0.241586 -0.0596156 0.122636 -0.430821 0.0739293 0.118985 -0.234701 0.0657378 0.00352096 -0.139338 -0.0464965 0.0329427 -0.179571 -0.171611 -0.131581 0.0221756 0.0174551 0.0383543 0.444599 -0.0571041 -0.0023257 0.214019 -0.0548056 -0.34939 0.308858 -0.0204281 Jak2-R-V 0.0318205 -0.205916 0.0391467 0.06458 -0.201605 -0.0885417 -0.0871702 -0.222365 0.295303 -0.20882 -0.269207 -0.379615 0.12607 -0.102423 0.0435401 0.110743 -0.571691 -0.125686 -0.0871359 -0.4228 0.15625 0.263519 -0.139852 0.0529418 0.131187 -0.317982 0.0317524 -0.300565 -0.321366 -0.05787 0.113844 0.286713 -0.263238 -0.65687 -0.0666544 -0.154069 0.532367 -0.199471 -0.0642357 0.279343 0.274502 -0.940995 0.053175 KEAP1-R-C Ku80-R-C 0.186706 0.352443 0.33366 -0.327186 0.414513 0.178145 0.281378 -0.459638 -0.315179 0.408523 0.696472 -1.80565 0.575495 -0.57378 -0.322462 0.2135 -1.16692 -0.0822295 -0.320224 0.337057 -0.279438 0.0420569 -0.769027 0.114598 -1.61121 -1.08147 -0.406269 -0.245526 -0.640588 -0.431133 -0.257139 -0.112224 -0.842796 -0.887138 0.458295 -0.873918 -0.369687 -0.881826 -0.278239 -0.198827 -0.0268081 -0.921942 -0.248915 LCN2a-G-C LDHA-R-C LDHB-M-E LKB1-M-C LKB1-M-E -0.116839 -0.132035 -0.107659 0.0491745 0.309153 0.255981 0.277651 0.0264357 0.0820156 0.204371 0.117043 0.778334 -0.0572802 0.293825 0.267939 0.0973101 0.671521 -0.13979 0.180108 0.395695 0.245012 0.146554 0.0412373 0.240191 0.139649 0.193174 0.187067 -0.0668386 0.336208 -0.0232323 -0.101853 0.0145952 0.416336 0.130339 -0.0147548 0.180439 -0.0507508 0.128695 0.00260409 -0.0770889 0.0826099 0.420369 0.0672798 Lck-R-V -0.253607 0.0467797 -0.189186 0.564929 0.196993 0.0734587 -0.104473 0.548183 0.2404 -0.368039 -0.641131 0.589584 -0.138697 0.233518 0.594805 0.593468 0.358727 -0.657919 -0.0441539 0.0952707 0.734506 0.17168 0.018791 0.485883 0.179863 0.539847 0.252072 0.0473495 0.36377 0.356788 0.0926103 -0.19185 0.30094 0.123664 -0.149873 0.222478 0.681407 0.456918 -0.0748318 0.289926 0.419327 0.364449 0.380108 MACC1-R-C MAPK_pT202_Y204-R-V 0.00181986 0.971207 -0.378646 0.00433917 -0.461866 -0.643436 -0.404975 -0.276806 -0.463291 -0.3471 0.234095 0.215661 -0.749274 -0.55679 -0.216574 -0.538756 0.421414 -0.4469 -0.488308 -0.353663 0.405346 -0.595041 1.74196 -0.0452726 0.434888 0.0473658 -0.284435 0.0351414 0.169241 0.397959 -0.291765 0.575609 -0.616258 0.365889 -0.437354 1.42384 0.0304375 0.396276 0.846864 0.198894 0.448308 -0.0481998 -0.40539 MEK1-R-V 0.0331994 0.0460845 0.109763 -0.058394 -0.361734 -0.257783 0.0696235 -0.861703 -0.249992 -0.183736 0.575251 0.341698 -0.170113 -0.00617167 -0.517391 0.188154 0.0264796 -0.269574 0.865923 0.0821682 0.490594 0.406769 0.0879217 0.0723209 -0.682532 -0.519382 0.540484 0.547352 0.0579314 0.0452192 0.545235 -0.0601957 0.410875 -0.171595 -0.44934 0.104561 -0.310788 0.406644 0.200591 0.031151 0.35256 0.0413153 -0.251813 MEK1_pS217_S221-R-V 0.00999737 0.184712 -0.178033 0.305399 0.1692 -0.3517 0.0626225 0.369563 -0.0392878 -0.187067 -0.0294194 0.506782 -0.203965 0.0606583 0.136739 0.00818671 0.267177 -0.270163 0.255355 -0.0550752 0.292246 -0.267322 0.230831 -0.202402 0.0527703 0.160913 0.124658 0.100971 0.385607 -0.0851539 -0.108561 0.170669 0.311818 0.098513 -0.0409475 0.439734 -0.00835137 0.324336 0.083932 -0.0336398 0.229739 0.365032 -0.118822 MIG-6-M-V -0.0528779 0.0696277 -0.121236 -0.0613514 -0.147767 -0.0816796 -0.115595 -0.115774 0.0839371 -0.197383 -0.134414 -0.0110256 0.0300288 -0.174094 0.156955 0.161447 -0.153516 -0.108969 -0.22737 0.0982608 0.198432 0.0179393 -0.200495 -0.194154 -0.0572055 0.295938 0.137602 -0.002548 0.182247 -0.0705418 0.0206687 0.16525 0.386275 0.040512 0.133095 0.00154184 0.00011762 0.0672971 0.131419 0.0741479 0.360575 0.29575 0.0827859 MSH2-M-C MSH2-M-E 0.0504917 -0.0436815 1.0216 -0.0499137 -0.0753394 -0.226193 0.733385 -0.556717 -0.0256667 -0.499103 -0.0075377 0.068978 -0.0814617 -0.0712289 -0.585094 0.179389 -0.724408 MSH2-M-V 0.0594937 -0.139799 -0.0970976 0.154149 -0.0801957 -0.239628 -0.00774002 -0.811231 -0.180357 -0.271939 0.151212 -0.369697 0.210015 0.267188 -0.156902 -0.463029 0.0663516 -0.083742 -0.721329 0.0887339 -0.0971758 -0.250292 -0.0381148 -1.11968 -0.334924 0.103178 MSH6-R-C -0.0587313 0.58094 -0.0827153 0.28515 0.466929 -0.616524 -0.167135 -0.580075 -0.889773 -0.301206 0.0468805 -0.948375 -0.260836 0.643448 -0.0451501 -1.03562 -0.82762 -0.0648678 -0.664891 0.498662 -0.418393 -0.311567 0.149655 -0.0457389 -1.08599 -0.00928759 MSH6-R-E 0.260462 0.0555795 2.01482 0.276319 -0.408374 0.0573919 1.17651 -1.0865 -0.255301 -1.40896 0.117983 0.361578 -0.0890337 0.233631 -0.760362 -0.0835023 -0.525258 MYH11-R-V -0.00745966 0.625135 -0.864831 -1.2961 1.49741 -0.733794 0.642476 2.39589 -1.58741 -0.837172 1.90807 -1.35423 0.495714 0.696129 0.695603 -1.90479 2.93826 -2.88631 2.25926 -3.40027 0.806576 -0.818056 0.16816 1.40555 0.680954 -3.03691 -1.50439 1.50918 -0.698097 1.3483 -1.76726 -1.37821 0.36179 0.0424315 -0.337764 2.48121 -1.97241 0.222786 -1.65784 0.345634 1.01027 -1.25831 0.279872 Mitochondria-M-V Mre11-R-C -0.152186 -0.143363 -0.141327 -0.109339 0.208629 0.0527039 0.243594 0.258582 -0.108044 -0.156399 0.0182144 0.381675 -0.0441408 0.0520581 0.167661 -0.0274221 0.597921 -0.054139 0.0547283 0.303241 0.217527 -0.0113949 0.202962 0.00676332 0.495376 0.113243 0.143865 -0.103737 0.158062 0.064136 -0.110495 -0.125131 0.229809 0.10477 0.0852655 0.405269 -0.129517 0.0605955 -0.0377191 -0.0957563 0.239111 0.446322 -0.00171759 Myosin-IIa-R-C 0.0615746 0.246696 -0.138577 0.24883 -0.0398219 0.363135 -0.214173 0.478809 0.361037 -0.399913 0.210479 0.138153 -0.0134401 0.434106 0.2008 -0.082673 -1.10954 Myosin-IIa-pS1943-R-V Myosin-IIa_pS1943-R-V -0.120079 0.113852 0.0614631 -0.233282 0.392985 -0.171073 0.0319143 -0.251718 0.297438 0.314133 -0.489707 0.16863 -0.35963 0.195503 -0.0109536 -0.368 -0.499712 0.464788 0.145908 -0.4341 -0.49551 0.0959895 0.0983338 0.071564 -0.909196 -0.516732 0.543066 -0.427 0.547898 -0.256101 -0.0203703 0.454573 0.0489196 -0.806587 -0.387371 -0.465178 -0.172616 0.364733 0.0852093 0.0543538 0.491172 -0.571964 0.376208 N-Cadherin-R-V -0.0216595 -0.131991 -0.198214 0.121694 0.49345 0.144648 0.289931 0.297275 -0.0399086 -0.131578 -0.167702 0.522917 -0.00322649 -0.0366838 0.15498 -0.0512259 0.899304 -0.0816515 -0.18042 0.394136 0.156698 0.250591 0.112619 -0.266512 0.599289 0.0889742 0.214464 -0.104277 -0.012353 0.10133 0.05936 0.109273 0.164211 0.0262553 0.110882 0.313739 -0.11622 -0.0468984 -0.111479 0.0275889 0.00130638 0.290093 0.0382026 N-Ras-M-V 0.0653026 -0.0991161 -0.0994261 -0.251323 -0.263427 0.0363439 -0.0705979 -0.065702 0.106681 -0.33838 -0.0437218 0.324728 0.0102919 0.00125766 0.220236 0.178062 0.212273 0.022197 0.0865999 0.166839 0.627852 -0.124046 0.0202271 -0.17638 -0.0858682 0.184931 0.0727267 0.114073 0.256487 0.178299 -0.0439172 -0.0745593 0.360845 -0.0599158 0.14507 0.0900967 0.0503293 0.16769 -0.0585909 -0.03416 0.322573 0.38161 0.187625 NDRG1_pT346-R-V -0.623644 2.29597 1.19512 0.945486 -1.28714 -1.23909 2.23114 -0.387216 1.72253 2.13717 1.76373 -0.520844 -0.287641 0.93286 -0.634273 -0.566995 0.996536 2.23231 1.38452 1.21061 -0.433274 1.54183 2.37054 2.00352 2.03061 1.64497 2.72892 3.22267 1.71628 0.162927 -0.225782 1.06897 2.09787 3.33999 0.626134 0.0806004 0.801589 2.3511 2.19548 0.265741 1.33438 1.92711 0.179128 NF-kB-p65_pS536-R-C -0.159288 0.320986 0.172727 0.828462 0.150404 -1.27448 -0.268189 -0.25779 -0.335406 0.911589 0.0539384 -0.589431 -0.359172 -0.623086 0.00315986 -0.439134 -0.61921 0.919532 -0.469704 -0.937025 -0.276838 0.100223 -0.785401 0.510497 -0.00361327 -0.316704 -0.154674 -0.506538 -0.16079 0.214457 -0.0807823 0.201567 -0.770434 -0.157373 -0.151131 0.193605 0.268455 -0.330922 -0.382095 -0.070273 0.0460727 0.00320153 -0.0986642 NF2-R-C -0.213133 0.23683 0.242203 -0.189519 0.224036 0.00894268 0.273285 -0.502557 -0.0231753 0.000170008 -0.0655815 -0.054737 0.145619 -0.000773515 -0.0101694 -0.0445189 -0.340066 -0.391998 0.0641237 -0.513306 0.00853539 0.0306992 -0.642595 0.257437 -0.74507 -0.30031 0.208271 -0.108376 -0.496753 -0.196845 0.0468882 0.44475 -0.305037 -0.0204925 0.108668 -0.324008 -0.140174 0.109449 0.0687936 -0.0577127 0.148905 -0.874593 0.0211709 Napsin-A-R-E Notch1-R-V -0.12692 0.592851 0.162623 0.551659 0.197577 0.622597 0.593542 -0.00113985 0.321476 0.871704 0.356245 0.136827 0.102695 -0.0866586 0.226547 0.206587 0.291968 0.618028 0.110057 0.869838 0.116397 0.384726 0.0968528 0.198346 0.454092 -0.395759 -0.0477124 -0.0631795 -0.0130473 -0.000790882 0.187602 0.426001 -0.248566 -0.0586064 0.0913143 0.119089 -0.0884759 0.0393422 0.419262 0.256905 0.095746 0.0141317 -0.117642 Nrf2-R-C Oxphos-complex-V_subunitb-M-E P-Cadherin-R-C -0.118976 0.682189 -0.0367845 -0.329504 -0.228455 0.253666 -0.122827 0.247797 1.0049 -0.400911 -0.0707581 0.250174 0.126687 0.100053 0.536926 0.794878 0.279272 0.151204 0.216014 0.208055 0.332052 0.0557366 0.422795 -0.0254775 0.276949 0.681959 1.30734 0.820929 0.335465 -0.515526 0.019672 0.836613 0.200996 1.01335 0.429165 -0.340255 0.0331841 0.79232 0.115233 0.764592 -0.0595272 1.09983 0.236849 PAI-1-M-C PAI-1-M-E -1.40251 1.01162 -0.61584 -0.641576 -0.0500772 -0.853232 1.45516 2.20075 0.0743486 0.771461 -0.425283 1.54231 0.436546 1.44941 0.547709 -0.267904 0.747083 -0.459084 1.79312 0.818493 0.224811 0.151245 1.08065 0.338416 1.41424 0.163703 0.31365 0.704314 0.992202 -0.613447 1.84097 0.985123 0.459335 0.33255 -0.125853 -0.371222 0.00680313 1.20189 1.25938 0.625303 1.33416 1.79169 0.376525 PAI-1-M-V PARP-Ab-3-R-C PARP1-R-V 0.0605061 0.128304 0.034156 0.119077 0.208482 -0.142095 0.120938 -0.128851 0.0237343 -0.235661 0.233895 0.0587483 -0.190814 -0.282822 -0.816363 0.732247 0.120797 0.149308 -0.28667 -0.0915418 0.575757 -0.251908 0.151706 -0.196734 -0.249038 -0.0197271 PARP_cleaved-M-E -0.033665 -0.476233 -0.211122 -0.347137 -0.279537 0.0263931 -0.247436 0.0265506 -0.0288793 -0.446926 -0.0604376 0.619257 -0.0616591 -0.180221 -0.000288123 -0.0100843 0.0398639 -0.122806 -0.00293386 0.156888 -0.386563 -0.207803 0.0112616 -0.133281 1.30376 -0.0202847 -0.0678533 0.109988 0.0617181 0.247175 -0.138593 -0.10277 0.140081 -0.0329431 -0.0867163 -0.124969 0.921362 0.0839304 -0.0832092 -0.160249 -0.48193 -0.211178 0.0637282 PCNA-M-C -0.0437553 0.158377 -0.263781 -0.155877 -0.339838 0.514248 0.133448 0.0484079 0.282396 -0.66747 0.265323 0.167837 -0.0667482 0.541177 -0.178707 0.239032 -0.519466 -0.125686 0.637615 0.034673 -0.365071 -0.186728 0.167686 0.453549 -0.951919 0.197297 -0.127438 0.223861 0.096613 -0.38235 0.415078 0.331371 0.453574 0.0373582 -0.0868405 -0.465326 -0.0642939 0.305823 0.12499 0.294783 0.194789 0.100403 -0.140041 PCNA-M-V PD-L1-R-V PDCD1-M-E PDCD4-R-C 0.00146342 -0.371497 0.792792 0.0921688 -1.0112 -0.14488 -0.258028 -0.000172498 0.169986 0.77898 0.601496 -0.793285 0.165568 -0.260787 -0.873412 -1.02939 -0.274035 0.333022 -1.74603 -0.26385 0.436374 -0.978791 0.00361895 0.719847 -0.419696 -0.650641 -0.0845914 -0.587978 -0.951985 0.679097 -0.0324171 0.615029 0.547725 0.415996 0.608898 -0.0511985 0.46725 0.182741 0.232933 -0.138969 -0.327734 -1.30143 -0.186497 PDK1-R-V -0.0604625 -0.146094 0.302895 -0.0236054 -0.0585465 0.0745585 0.190768 0.1961 -0.111075 0.0543004 -0.110342 0.351423 0.250665 0.4855 0.0690836 -0.042497 0.185861 0.244283 0.200113 0.260105 0.0808556 0.257226 -0.232186 0.141865 -0.323102 -0.0269242 -0.0288078 0.0656204 0.226035 -0.1531 0.0576092 -0.0289253 0.32028 0.0428271 0.135274 -0.0483751 -0.0894526 0.271745 0.0515449 0.190066 0.185852 0.239851 -0.270556 PDK1_pS241-R-V -0.0272906 -0.309143 0.44258 0.013233 0.15062 0.0535458 0.430878 0.0826239 -0.17266 0.394406 -0.0805835 -0.342701 0.173537 0.95791 0.0546012 -0.011514 -0.0642048 0.318497 0.297387 -0.0223332 0.0657156 0.168446 -0.656238 0.299808 -1.41754 -0.168117 -0.0738241 0.17326 0.0740141 -0.187855 -0.0367502 -0.0725816 0.18052 0.0321477 -0.0201269 -0.0721362 0.0337543 0.399039 0.231071 0.146972 -0.0171653 0.0952122 -0.350196 PEA15-R-V -0.373504 -0.00572772 -0.115008 -0.48358 0.286142 -0.102621 0.11955 0.520329 0.0435251 0.0394484 -0.0361012 -0.385264 -0.136039 0.411495 0.656299 0.0232663 0.471543 -0.37388 -0.111018 -0.487425 0.306754 -0.305741 -0.733408 -0.253984 -0.443837 0.0451151 0.00742734 0.109153 -0.0654876 -0.160525 0.33005 -0.118327 0.398015 0.0599734 -0.0524986 -0.0155848 0.0180187 0.119625 -0.0868372 0.140829 0.284525 0.184991 -0.00205979 PEA15_pS116-R-V -0.219785 -0.120441 0.15409 0.0161182 0.112437 -0.157009 -0.0538181 0.0465068 -0.144876 -0.0835135 -0.093121 0.215867 0.0953243 -0.233625 -0.0250306 -0.166569 0.469534 -0.180472 -0.370277 0.0324573 -0.364756 0.0857526 -0.117454 -0.218456 0.235405 -0.349121 -0.0220399 -0.103835 -0.29012 -0.140269 -0.0741162 0.265786 -0.0889541 -0.33457 0.00938833 0.310047 -0.10402 0.0277305 -0.113223 0.320683 -0.152114 0.15246 -0.215105 PI3K-p110-alpha-R-C 0.0570925 -0.00493441 -0.0729008 0.293627 0.0629798 0.539389 0.439086 -0.169103 0.0547069 0.514785 0.682785 -0.487564 -0.0213462 0.206871 0.047231 0.115166 0.14409 0.0358116 -0.0844093 0.0713175 -0.205221 -0.00963586 -0.356871 -0.00141236 -0.324009 0.1785 0.0770764 0.219228 -0.0148444 -0.0491537 -0.0329617 -0.0872075 0.301995 0.373131 -0.14905 0.275025 -0.118146 -0.0639996 -0.0524171 0.234112 0.0707269 0.317359 0.0391009 PI3K-p85-R-V -0.273321 -0.109988 0.25635 -0.242335 0.211677 0.290244 0.335194 0.336034 0.233163 -0.10719 0.1337 0.0596667 -0.0163603 0.309416 0.49304 0.262575 0.328771 -0.316529 -0.318379 -0.346828 0.344444 -0.341921 -0.89396 0.282041 -0.50564 0.178429 0.104118 -0.000108407 0.167351 -0.0765629 0.0121042 -0.306852 0.215354 0.178919 -0.431097 0.316825 0.0618267 0.393053 -0.0936065 0.131441 0.399174 0.12622 0.101176 PKC-alpha-M-V -0.838592 -0.0843474 0.203386 -0.52845 0.637259 -0.491449 0.0194302 -0.627297 -0.00964338 -0.587388 0.11444 -0.291202 -0.291294 -0.29406 -0.0204278 0.0644165 0.960153 -0.139803 0.171995 0.458974 0.380628 -0.524613 -0.751122 0.104743 -1.32933 -0.538229 -0.106683 -0.217553 -0.607666 0.2536 0.711933 0.0780623 -0.846156 -0.127754 -0.735314 0.84022 -0.158273 -0.221257 -0.649341 0.085481 0.10278 -0.528375 -0.0965178 PKC-alpha_pS657-R-C -0.905021 -0.149023 0.209756 -0.52176 0.557098 -0.434209 -0.119146 -0.405077 -0.287735 -0.65425 -0.0492481 -0.0666027 -0.200759 -0.206931 -0.0674072 0.126319 1.06319 -0.300218 0.207863 -0.138097 0.523092 -0.490686 -0.887891 0.150921 -0.877225 -0.48302 -0.094574 -0.165858 -0.701963 0.187446 0.708338 -0.104616 -0.528468 -0.175553 -0.656263 0.898717 -0.0427228 -0.187739 -0.754203 -0.0434563 0.0128805 -0.274862 -0.165222 PKC-alpha_pS657-R-V PKC-delta_pS664-R-V -0.0268331 -0.116184 0.160558 0.178023 0.064051 -0.23443 -0.206857 -0.0785977 -0.0818917 -0.181546 -0.195317 0.0275129 0.410171 -0.0608748 -0.381159 -0.279147 0.350122 -0.133655 -0.17403 -0.0279791 -0.25022 -0.270534 -0.207237 0.0226817 0.0383949 -0.351458 0.00864994 -0.301459 -0.395699 -0.0347237 0.275279 0.0755985 -0.437392 -0.581729 -0.253115 0.0666427 0.197511 -0.144865 -0.245709 -0.213451 -0.0324069 -0.612546 -0.134188 PKC-pan_BetaII_pS660-R-V 0.272413 -0.0305444 0.69338 -0.1398 0.0340028 -0.436754 -0.177928 -0.662223 -0.0360212 0.547783 -0.229453 -0.147046 0.542983 -0.0165065 -0.454463 -0.0975802 0.250222 0.190979 -0.319683 -0.785053 0.263296 -0.663838 -0.433547 0.415443 -2.04949 -0.30089 -0.123272 -0.284716 -0.418383 0.0757844 0.0762551 0.186447 -0.3922 -0.2267 -0.468498 0.142832 0.328018 0.208815 -0.161086 -0.104016 0.16779 -1.04573 -0.210175 PKM2-R-C PR-R-V -0.11834 -0.152267 -0.253466 0.00971143 -0.0906133 0.0116346 -0.0247159 0.130147 -0.0706668 -0.270595 0.010347 0.432844 0.0675671 0.0557749 0.109344 0.0542956 0.515595 0.00746414 0.156038 0.152678 0.0782089 0.0469062 0.0646466 0.00184293 0.270649 0.110039 -0.0375573 0.0127193 -0.0109989 0.227097 -0.11507 -0.0372216 -0.0403242 -0.00164932 0.112006 0.723436 -0.0910055 0.0435774 -0.101019 -0.189671 -0.0866789 0.315981 0.065082 PRAS40_pT246-R-V -0.0188865 0.0713813 0.0605606 0.560475 -0.188748 -0.383441 -0.155467 -0.405272 -0.0118248 0.271347 -0.0643325 -0.182501 -0.0762734 -0.354326 -0.348754 -0.270422 -0.236059 0.12562 -0.366644 0.0157978 -0.294795 -0.127285 -0.156288 -0.233361 0.661126 -0.151487 -0.00212816 -0.00410419 -0.116138 0.0380436 0.0763556 0.0973157 0.0272229 -0.0741186 -0.0462113 0.0432096 -0.0175532 -0.259978 0.141079 -0.193732 -0.048526 0.185678 -0.171278 PRDX1-R-E 1.21591 -0.178375 -0.43639 -0.319 0.251413 -0.518521 -0.65357 0.178772 0.288825 0.0492335 0.409727 -0.29346 1.58935 0.199917 0.248981 -0.368444 -0.328436 PRDX1-R-V -0.322986 -0.154344 -0.435609 0.234266 0.753132 0.797576 0.128204 -0.210724 -0.0157416 0.331785 -0.181476 0.184698 0.0853559 0.0927517 -0.538004 1.04055 0.322943 -0.0719379 -0.447426 0.0985799 0.16192 -0.0494209 0.255281 0.268912 0.458221 -0.21145 PREX1-R-E 0.127861 -0.255663 -0.297196 0.324504 0.0818862 0.550609 0.6143 0.65915 0.552334 -0.0899995 -0.287999 0.62405 -0.487242 0.829294 0.995653 0.370517 0.386838 -0.307573 0.00526685 -0.482087 0.434553 0.261307 -0.442149 0.608072 -0.195301 0.666275 0.270335 0.334005 0.973411 0.131451 -0.19024 -0.0162462 0.641799 0.195196 -0.325133 -0.108984 0.486607 0.783801 -0.0515162 0.299993 0.574763 0.782804 0.509845 PREX1-R-V PTEN-R-V 0.339563 0.26966 0.661534 0.54241 0.113571 0.617442 0.529872 -1.22517 0.108554 0.322766 0.170793 -0.379743 0.539919 0.103437 0.102062 0.0222999 -1.3954 0.884362 -0.250809 0.0979282 0.117322 0.548472 -0.558433 0.305186 -1.43374 -0.414264 0.0666299 -0.00465611 -1.33355 -0.130921 0.123492 0.553483 -2.10019 -0.423812 0.192895 -1.66205 0.0854346 -0.316556 0.247532 0.0058075 0.0134373 -0.908653 0.350118 PYGB-AB2-R-V PYGB-R-V PYGL-R-E PYGM-M-C Paxillin-R-C -0.104842 -0.159679 0.368416 -0.120893 0.543003 0.389627 0.00824269 -0.87525 -0.252008 0.0681489 0.168848 0.197586 0.342141 -1.01555 -0.920593 -0.320652 -1.14303 0.734595 0.0622502 -0.056006 -0.0381563 0.103624 0.195134 -0.468073 -0.960143 -3.1868 -0.566063 -0.641243 -2.40572 -0.137976 -0.031856 0.417688 -2.43729 -3.37654 0.00218065 -0.659409 -0.259905 -1.55086 0.312816 -0.298591 0.345376 -2.88702 -0.0289278 Paxillin-R-V RBM15-R-V 0.15006 0.21621 0.117833 -0.413642 -0.332159 0.431952 0.49522 -1.46741 0.27499 0.238512 0.272009 -1.50624 0.236548 -0.326546 -0.434161 -0.27529 -2.32934 0.117477 -0.0502909 -0.226832 -0.394326 -0.12978 -0.612704 0.0667416 -1.23616 -0.891443 0.212795 -0.0705305 -1.87903 -0.779923 0.232513 0.185081 -1.72229 -0.566648 0.386986 -2.15882 0.496744 -0.470875 0.03023 0.0189313 -0.0401971 -2.03845 -0.117557 Rab11-R-E -0.159767 0.0255567 0.146782 -0.11246 -0.193337 -0.415144 -0.241931 0.121235 -0.129924 -0.267438 -0.400106 0.518701 0.183971 -0.289821 0.0600823 0.0296816 -0.119845 -0.152754 -0.280226 0.293314 0.185871 -0.0516072 0.0453995 -0.120464 0.0498546 -0.101471 0.0322815 -0.147891 0.160171 -0.0638262 0.043782 -0.077597 0.299112 -0.0216879 -0.0179145 0.100155 -0.0511343 -0.00743185 0.0295151 -0.0499892 0.166121 0.246716 -0.23203 Rab11-R-V Rab25-R-V -0.244161 -0.21654 0.414308 0.211839 -0.40279 -0.211509 -1.03763 -0.389885 -0.596711 0.64042 -0.303769 -0.16011 0.599792 -0.622362 -0.556299 0.453196 -0.458058 0.0955632 -0.50337 0.225353 -1.41428 0.221532 0.188926 -0.449716 -0.346672 -0.827268 -0.103597 -0.997719 -0.498336 0.281792 1.03288 -0.46925 -0.770072 -0.394323 -0.260583 -0.906236 0.266421 -1.121 0.0667262 -0.725699 -2.22022 -1.16368 -0.218297 Rad50-M-C Rad50-M-V 0.124328 -0.11745 -0.182357 -0.210838 -0.0822024 -0.174327 -0.144935 -0.600693 0.00622125 -0.256605 -0.121427 -0.286345 -0.0168012 0.410106 -0.159854 -0.188772 -0.144425 -0.533244 -0.312544 -0.398135 -0.294993 -0.400527 -0.834713 0.125892 -0.694438 0.143224 0.143096 0.0435129 -0.155786 0.243183 -0.0234306 0.158843 -0.0717089 0.0635804 0.147286 -0.345521 -0.279537 0.124086 -0.000336684 0.127932 -0.051621 -0.154222 0.0669537 Rad51-M-C Rad51-M-E -0.000587244 -0.0357262 0.0869293 -0.0656952 -0.153149 -0.0682032 -0.0682692 0.154008 0.16124 -0.155954 -0.125686 -0.0476645 -0.156172 0.235063 0.0203358 0.045648 -0.366455 Rad51-R-V 0.1282 0.401412 -0.346614 0.127994 -0.410128 0.549402 0.00591845 0.537518 0.114605 0.304702 -0.106848 0.10331 0.230181 -0.180523 -0.215394 -0.143718 0.395102 -0.327053 0.654584 0.0813316 0.200459 -0.284637 -0.165035 0.112916 0.658243 0.119885 Raptor-R-V 0.0443818 -0.123939 -0.087152 -0.211122 0.534585 -0.0151369 -0.203161 -0.390716 -0.0340771 -0.0116062 0.0468416 -0.188435 0.071075 0.130696 0.0940081 0.0503677 0.0197919 0.313104 -0.296283 -0.323185 0.248742 -0.0887572 -0.664869 -0.10673 -0.546172 -0.0382657 -0.0122607 -0.0979006 0.172957 0.000398461 -0.0749443 -0.0520408 -0.0458792 -0.110473 0.0736776 0.483693 -0.0324722 -0.0500574 -0.135041 0.118863 0.312529 -0.00884305 0.00779833 Rb-M-E 0.0136324 -0.061693 -0.0503498 0.0714134 0.0757263 -0.200502 0.0529398 -0.0741504 0.166379 0.0167028 0.106358 0.589305 0.00076318 -0.0230995 0.0334877 -0.121241 -0.0526706 -0.0650153 -0.204944 0.144302 -0.0428386 0.222448 0.160571 -0.0992232 1.13309 0.084586 0.0177625 0.0168203 0.276138 0.127124 -0.254046 0.172964 0.461077 0.0130792 -0.0738 0.212956 -0.217634 0.241963 0.0736856 0.206874 -0.21898 0.211366 -0.0242573 Rb_pS807_S811-R-V 1.04238 0.252563 -0.0670983 1.23835 -0.124095 -1.07675 -0.419606 0.443771 -0.495027 1.11341 0.557251 -0.973013 -0.962865 -0.11743 -1.07156 -1.33403 -0.575374 -0.187906 -0.970875 -0.749139 -0.76518 -0.311743 1.31907 -0.138395 0.522268 0.212454 -0.815471 -0.599082 -0.320237 -0.051687 -0.365577 0.370618 0.420559 -0.0906361 0.0190816 -0.610687 -0.34025 0.0812337 0.0677895 -0.0429185 -0.671 -1.09584 -0.330352 Ret_pY905-R-E Rictor-R-C -0.473838 -0.0371816 -0.399627 -1.08045 1.84063 -0.120273 0.302837 0.792294 -0.7068 -0.404725 2.13948 -1.73188 -0.269203 0.2787 0.203526 -0.971905 3.59149 -0.486013 2.22953 -1.18817 1.078 -0.749443 -0.833491 0.690579 -0.989693 -1.18224 -0.600072 1.52078 -0.819745 3.20764 -0.338036 -0.649878 -0.0625198 -0.325619 -0.419381 3.95646 -0.56577 -0.334931 -0.913497 0.971869 1.50415 -1.44236 -0.235161 Rictor_pT1135-R-V -0.177901 -0.00493441 -0.0383867 0.11224 -0.122289 -0.318508 -0.234926 0.0513394 0.0153271 -0.0188536 -0.00371599 0.205022 -0.0243383 -0.145954 0.193873 0.0238345 -0.00443281 0.0141836 -0.0410965 0.0473264 0.386452 -0.0944458 0.061753 -0.137244 0.156519 0.0603259 -0.0348474 -0.000556029 0.327611 0.130681 -0.133613 -0.0793714 0.191438 0.065467 0.0348231 0.554663 -0.0754518 0.118719 -0.137368 -0.0887978 0.292983 0.33521 0.000832717 S6-R-C S6-R-E 0.194072 0.257376 0.331875 0.146406 0.175891 0.905674 0.420296 -0.455579 0.618493 0.598823 0.157072 -1.0346 0.210433 0.113226 -1.10449 0.225194 -0.777788 0.962263 0.62739 -0.591456 -1.031 -0.126169 -0.124465 0.00184293 0.393279 -1.43976 -0.161664 -0.510257 -3.75658 -0.614361 0.216783 -0.0782823 -2.73339 -0.862499 0.0161921 -2.15977 0.0842201 -0.130234 0.11813 -0.202293 -0.152514 -3.29832 0.227841 S6_pS235_S236-R-V 0.938405 0.509534 -0.751159 1.27554 -0.87339 -0.679456 -0.430452 0.354468 0.558258 0.715536 0.24697 -0.290931 0.0654232 0.247748 0.265842 0.769797 0.425291 0.557638 0.212835 -0.530113 0.652612 -0.488677 0.54241 0.783675 0.624451 0.023682 -0.465505 0.0288107 -1.30401 -0.0962736 -0.26408 1.15068 -0.571678 -0.0903802 -0.499075 -0.923969 0.232655 -0.272421 0.553714 0.517644 0.321589 -1.23572 0.477692 S6_pS240_S244-R-V 1.05019 0.311231 -0.540509 0.984561 -0.672851 -0.481634 -0.437438 0.222731 0.411554 0.237916 0.115864 -0.589235 0.195034 -0.126883 -0.00222637 0.537387 0.340526 0.586304 0.438689 -0.439527 0.4929 -0.468587 0.213697 0.317856 0.633648 -0.0572058 -0.247297 0.218073 -1.23224 -0.0462002 -0.196332 1.03584 -0.922242 -0.416455 -0.290146 -0.628191 -0.0263716 -0.417044 0.411299 0.58291 0.348848 -1.90457 0.334403 SCD-M-V 0.191538 -0.384176 0.133476 0.245486 -0.148591 0.0540565 -0.121721 -0.312041 0.0346812 -0.191964 0.0133728 0.0437896 -0.0502163 0.000773515 -0.0677798 -0.133665 -0.00304922 0.124025 -0.180894 -0.038543 -0.227936 0.464496 0.134569 -0.177784 1.23049 -0.0576445 -0.104349 0.115494 0.318097 0.240348 -0.220031 -0.152933 0.53864 -0.0731857 0.0359514 -0.0334933 -0.0570279 0.0023257 0.0655304 -0.0962619 -0.350509 -0.000254029 0.05207 SCD1-M-V SETD2-R-E -0.26288 -0.0296181 0.0383619 -0.0063414 -0.206841 -0.178871 -0.0148053 -0.066564 -0.0184272 -0.268054 -0.328635 0.973699 0.245265 -0.226107 0.251587 0.151171 -0.0310884 0.00825523 -0.148947 0.645732 0.0458118 -0.139396 -0.0184571 0.149844 0.858205 -0.126888 -0.00565205 -0.0485885 0.126786 -0.0331652 -0.116511 -0.11981 -0.153831 0.0155467 0.283295 0.264094 0.96162 -0.0841309 0.0111065 -0.0386834 -0.0711695 0.239115 -0.0694424 SF2-M-V 0.114085 -0.202186 0.127571 -0.236367 -0.342145 -0.16905 -0.205072 -0.487712 0.00113772 -0.368952 -0.112043 -0.067368 -0.232997 0.0268443 -0.104476 -0.342928 -0.291673 0.0526204 -0.25849 0.0998106 -0.784329 -0.0667013 -0.0494683 -0.21145 1.93092 0.169284 -0.109725 0.14998 0.459003 0.305355 -0.142957 -0.123321 0.556746 0.28747 -0.233718 0.0822227 -0.167689 0.304708 0.0699924 0.164822 -0.814898 0.00341186 -0.00504718 SHP-2_pY542-R-C -0.158086 0.408664 -0.0347232 0.349245 -0.542927 -0.40578 -0.468513 -0.444991 -0.173501 0.187848 -0.253378 -0.0230364 -0.269774 -0.519331 -0.352873 -0.489211 -0.207202 0.254058 0.809866 -0.247963 -0.780656 -0.023233 0.975694 -0.209549 0.189301 -0.0725301 -0.18368 0.110079 -0.0316138 0.24144 -0.249262 0.36238 -0.706579 -0.221599 -0.00218065 0.668811 0.112345 -0.0375916 0.422815 -0.204272 -0.856762 -0.733087 -0.221046 SLC1A5-R-C 0.516613 0.261018 0.542447 0.10946 0.26238 0.127719 -0.154167 -0.609645 -0.00759878 -0.818028 0.00165144 0.267202 0.00115197 0.345863 1.33134 -0.0463252 0.937109 STAT3_pY705-R-V -0.307126 0.465439 -0.234347 0.603353 0.514689 0.26068 -0.160236 0.00219938 0.337312 0.431493 0.677421 -0.183819 -0.256661 0.452382 0.0944936 -0.121803 0.338325 0.236824 0.094331 -0.416075 0.38355 0.357876 -0.110943 0.322035 -0.250029 0.55093 0.411204 0.566129 0.410159 0.0894893 0.0791648 -0.0617242 0.651895 0.398386 0.0408793 1.61985 0.153586 0.646036 -0.204807 0.266019 0.260469 0.195754 0.243059 STAT5-alpha-R-V 0.078809 -0.587645 0.17395 -0.174243 0.572454 0.220397 0.493396 -1.10457 0.110339 0.491205 -0.376146 -1.49369 -0.40492 -1.09358 -0.0286212 -0.253617 -0.691921 0.350551 -0.551496 -0.798257 0.582265 -0.0261234 -1.15509 0.588241 -1.57627 -1.20269 -0.158326 -0.840929 -2.10068 0.110907 0.219103 -0.167496 -2.60246 -2.16157 -0.794317 -0.464407 0.98959 -1.59197 -0.53057 -0.0535064 0.893389 -2.24692 0.233688 Shc_pY317-R-C Shc_pY317-R-E -0.107246 0.105227 0.0302353 -0.0209452 -0.0964272 -0.157629 0.0665425 -0.346184 -0.536648 -0.0806698 0.100007 -0.805467 0.0272039 0.418195 0.267833 -1.11442 -0.428742 -0.147162 -0.763991 0.183566 -0.298703 0.314906 -0.128262 -0.531098 -0.764155 0.114244 Shc_pY317-R-V 0.16822 -0.337423 -0.259838 -0.277692 -0.200356 0.0773575 -0.285551 0.301852 -0.0876766 -0.144856 0.304148 0.194413 0.00427286 -0.139589 0.665304 -0.235215 -0.472567 Smac-M-E 0.173725 -0.11729 0.186949 0.102112 0.072572 0.42612 -0.405694 -0.431937 -0.188862 -0.287123 -0.185932 0.145589 -0.0652284 0.585722 -0.338174 -0.136099 -0.922913 -0.746716 -0.348665 -1.02889 -0.650287 -0.170809 -0.362299 -0.00112057 0.00321167 0.358154 -0.447831 -0.0775526 0.171806 -0.0790992 -0.507391 -0.497212 0.191055 0.0161313 -0.0858901 -0.551403 -0.300958 -0.0033225 -0.0930215 -0.0246283 -0.721086 0.0420863 -0.243923 Smad1-R-V -0.15909 0.301634 0.202537 0.270979 0.32282 0.467068 -0.11684 -0.0527079 -0.0372336 -0.00807023 0.00425193 -0.407205 0.30121 0.503467 0.0565117 0.159885 -0.175782 0.329801 0.275083 0.139571 0.156815 0.248662 -0.507401 0.102794 -0.129139 -0.0038226 0.0189043 0.629055 -0.316233 -0.166307 -0.038539 0.149977 -0.484246 0.187324 0.436493 -0.103924 -0.00620766 0.113413 -0.163276 0.0401217 -0.151898 -0.0573806 0.367889 Smad3-R-V -0.0517257 -0.11777 0.490802 0.145378 0.0378476 -0.0661921 -0.0454239 -0.465643 -0.0988757 0.0559666 0.107245 -0.23519 0.414542 -0.230213 0.087663 0.191415 -0.333262 -0.010077 -0.307469 -0.210318 -0.0117643 0.127002 -0.266506 0.179874 0.263738 -0.0658101 0.011331 0.00713845 0.0628434 -0.164114 -0.153474 0.0289199 0.175982 -0.196334 0.0896562 0.0854223 -0.125226 0.153083 0.0020382 -0.122742 -0.0726937 0.0236709 -0.0670082 Smad4-M-C Smad4-M-V 0.0890284 -0.198862 0.0467781 -0.309666 -0.186944 0.251885 -0.119146 0.0163805 0.0991449 -0.18974 -0.148589 0.708268 -0.0356554 0.047421 -0.0996065 -0.189814 0.139792 0.0314406 0.287026 0.128114 -0.155346 -0.000748559 -0.129153 -0.0758871 0.499198 0.0324429 0.00466716 0.112417 0.14892 -0.0329522 -0.122861 0.0740643 0.080808 -0.00938289 0.0599957 -0.176466 -0.144603 -0.0504523 -0.0704393 -0.101725 -0.394934 0.389365 -0.0210468 Snail-M-E -0.0668399 -0.0872102 -0.0567805 -0.221331 0.080257 -0.250435 -0.11724 -0.250489 0.241585 -0.219604 -0.0981545 0.7342 -0.142006 -0.120159 0.0433909 -0.097276 0.0133315 -0.169621 -0.0703958 0.175105 -0.430714 0.158623 0.0967166 -0.0689734 2.02984 0.0928793 0.0461018 0.0925842 0.495989 0.161607 -0.147857 0.1185 0.709515 0.207454 0.106379 0.292999 0.0326738 0.202041 0.196636 0.0941288 -0.441885 0.420024 0.108316 Src-M-V 0.836281 -0.378532 0.940632 -0.643396 -0.666661 -0.160083 -0.696524 -0.842714 -0.0816128 -0.814666 -0.669624 0.185222 0.62037 -0.235981 0.0828683 0.266935 -0.54874 -0.740486 -0.346837 -0.548529 -0.482607 -0.321453 -0.602456 -0.154277 -0.831715 0.0504242 0.159683 -0.207129 -0.0846081 0.209215 -0.260815 0.187076 0.0181642 0.26254 -0.240394 -0.241086 -0.28076 -0.270059 -0.0150557 -0.170796 -0.329135 -0.197185 -0.457367 Src_pY416-R-C 0.112297 0.585618 0.28914 0.915184 -0.508673 -0.748894 -0.433873 -0.509472 -0.533441 0.67919 -0.342168 0.245495 -0.39105 -0.21132 -0.0868049 -0.674983 -0.102257 0.153256 1.02909 -0.106199 -0.992973 0.317784 0.989462 0.508461 0.132014 0.679928 0.097997 0.639341 1.62886 0.409837 -0.504254 0.741768 0.0709774 0.527593 0.331859 0.483438 0.441994 1.04335 0.298244 0.189012 -1.03075 -0.378921 -0.0821953 Src_pY527-R-V 0.924562 0.173683 0.90331 0.755236 -0.831071 -1.61826 -1.31979 -0.504931 -0.496918 0.0342409 -0.165887 0.523483 -0.136358 -0.557873 -0.965427 -1.48268 0.0535972 0.0664936 0.158746 -1.22597 0.202169 0.225885 0.296891 -0.0208266 -0.368551 0.211314 -0.205552 0.34184 -0.0954459 0.829254 -0.960266 0.545969 -0.116576 0.576477 -0.363903 0.198532 -0.471692 0.198429 0.561271 -0.670493 -0.0768296 -0.58598 -0.418176 Stathmin-R-V -0.0912362 0.0174786 -0.170415 -0.196462 0.0391924 0.429343 0.184929 0.302229 0.0209481 -0.253345 0.14461 0.628263 -0.195564 0.0994018 0.316275 0.146691 0.457306 -0.125686 0.279532 0.373848 0.317622 -0.151233 0.159135 -0.261364 0.720579 0.165035 0.0646633 0.0761486 0.362073 0.0772148 -0.062796 -0.00456028 0.316717 0.117004 -0.116768 0.340494 -0.0637295 0.0937251 -0.0866001 0.0258064 0.202859 0.58645 0.055067 Syk-M-V 0.246299 0.515994 0.108343 -0.43731 0.616878 0.39085 0.810418 -0.374426 0.406586 0.926606 -0.209029 0.882961 -0.236307 0.448445 0.677492 0.625394 -1.15368 -0.396945 -0.241589 0.0456025 0.254034 -0.106588 -0.23214 1.31517 -0.768518 0.355072 0.319975 0.37843 -0.219876 -0.398037 0.26937 -0.232549 -0.584575 -0.267395 0.403714 -1.96648 0.922139 0.440813 -0.358276 0.497419 0.656278 -0.371398 0.676218 Synaptophysin-R-E TAZ-R-C TAZ-R-V -0.11145 -0.0471066 -0.245879 -0.0352219 0.518956 0.300448 0.220802 0.201782 -0.00113772 0.0351264 0.131743 0.30895 0.0321678 0.159505 0.228388 0.0209458 0.637042 -0.113762 0.209657 0.0783144 0.361268 0.338071 0.317331 0.0234427 0.79274 0.177283 0.0450498 0.00135294 0.099317 -0.00273835 -0.0437069 0.0223197 0.209116 0.0687801 0.049295 0.349311 -0.15286 -0.0163749 -0.00447619 0.09052 0.329579 0.26844 0.0134801 TFRC-R-V 0.184942 -0.538579 -0.274685 -0.314627 0.99819 0.652356 0.131626 -0.311265 0.208675 0.297866 0.274708 0.391593 0.0172348 0.655695 -0.214665 0.410669 -1.32199 -0.949551 -0.258991 0.131317 -0.773923 0.109384 0.32784 0.00184293 2.46293 0.390699 0.873036 0.26305 0.662577 -0.473105 -0.176827 -0.222099 1.70671 0.440231 0.785706 -1.20337 0.4164 0.420777 0.854121 0.327862 -0.423182 0.221315 -0.0329992 TIGAR-R-E TIGAR-R-V -0.207723 0.25839 -0.0530573 -0.111677 0.103484 0.38937 0.116588 0.00103457 0.261681 0.0944387 -0.138181 0.11831 0.0141507 0.271469 0.221118 0.105919 0.0186125 0.238797 0.0327391 2.47328 0.184783 0.115574 -0.331267 0.0336327 0.0429055 0.20885 0.0542902 0.00888555 0.321174 -0.251366 0.0599673 0.105276 0.350845 0.0834959 -0.0251958 0.0182022 0.0486984 0.38111 0.00208962 0.280076 0.437161 0.290757 0.0752864 TSC1-R-C -0.387028 0.0648083 0.174964 -0.798023 0.25279 0.313673 0.273936 -0.306538 -0.0722889 0.043689 -0.0416852 -0.31007 -0.231111 0.296869 -0.151239 0.0457799 0.739915 0.232029 0.32735 -0.15244 0.0709974 -0.623895 -0.866127 -0.0685584 -1.46149 -0.381175 -0.221781 -0.0571509 -0.692992 -0.164986 0.180231 -0.248212 -0.580477 -0.343333 0.243956 0.904281 0.256431 -0.195244 -0.31065 -0.0187394 0.0546922 -0.381229 -0.260358 TTF1-R-V 0.0372789 0.0825865 -0.181506 -0.057555 0.100886 0.0443873 0.0660668 0.00980368 -0.0263247 -0.0369833 0.24202 0.0630478 0.00158437 -0.0567237 -0.00949528 -0.162939 0.038591 -0.0704831 0.281854 -0.162903 -0.0823139 -0.100607 -0.101992 0.22319 0.31274 -0.168765 Thymidilate-Synthase-M-C Transglutaminase-M-V -0.351901 -0.0637653 -0.00655655 0.171996 0.631056 0.67794 0.657359 0.781655 -0.0129768 -0.479933 0.30866 0.369684 -0.247069 0.117304 0.290936 0.403161 1.63802 -0.521331 0.123541 1.41142 0.106892 0.330468 -0.169141 0.560921 -0.585796 1.77144 0.153115 -0.0459491 0.167637 0.0336021 0.115755 0.151294 0.211062 -0.127458 0.162613 1.10088 0.133029 0.116243 0.0892301 0.21819 0.821731 -0.0476577 -0.16744 Tuberin-R-C Tuberin-R-E -0.243887 -0.00204792 0.104454 0.000587244 0.351646 0.169752 0.146356 -0.748712 0.0381621 0.521893 0.18106 -1.16959 -0.33818 -0.059222 -0.155586 -0.0407723 -0.675128 0.78013 -0.205602 -0.363151 0.282026 0.036143 -0.508412 0.09654 -1.7417 -1.12791 -0.213121 -0.202582 -1.8705 -0.00345342 0.23665 0.20778 -2.36354 -1.32019 0.283559 -0.520195 0.476449 -0.610114 -0.165559 0.21515 0.0703003 -1.99994 -0.202702 Tuberin-R-V Tuberin_pT1462-R-V -0.16118 -0.0786429 -0.139545 0.707631 -0.0413377 -0.232318 -0.160143 0.0631353 -0.277673 0.222158 -0.047077 0.0469277 -0.143901 -0.00171125 -0.182233 -0.203573 0.00304922 0.383904 -0.272287 -0.168303 -0.202451 -0.0456227 -0.157289 -0.104015 -0.188958 -0.196583 -0.246785 -0.05387 -0.306195 0.513627 -0.0363865 0.23316 -0.29379 -0.0532747 -0.0466848 0.393028 0.157222 -0.21481 -0.15912 -0.27996 -0.413138 -0.200911 -0.106611 VEGFR2-R-C VEGFR2-R-V -0.287152 -0.0248587 -0.00672891 -1.09905 0.456798 -0.260394 0.0512752 0.328777 -0.353448 0.162139 -0.471796 -1.12501 0.463136 -0.536767 0.0694074 0.0237488 0.962107 0.172617 0.322819 0.0334425 -0.233468 -0.702173 -0.324428 0.183028 -2.44513 -0.318406 0.0421184 -0.0732041 -0.645297 -0.00187505 0.363717 0.0992934 -0.974109 -0.319684 -0.414731 0.651033 0.245876 0.353446 1.0072 -0.343447 -0.0798715 -0.520141 0.146324 VHL-M-C XBP1-G-C 0.228855 -0.483817 -0.198475 0.420207 0.29381 -0.220359 -0.0730035 0.108998 -0.176263 -0.165122 -0.41459 -0.117961 -0.058849 0.272039 -0.0622135 -0.467248 -0.277413 0.161539 -0.0297706 -0.103273 0.552654 0.379675 -0.0727436 0.162403 -0.0689234 -0.470124 -0.220427 -0.19128 -0.39627 0.5881 0.165673 -0.114374 -0.476835 -0.391291 0.090642 1.44914 -0.345122 -0.28271 -0.270984 -0.0394386 0.348597 -0.630985 -0.0405142 XRCC1-R-C XRCC1-R-E 0.166622 0.00932514 -0.638626 -0.305502 -0.0630856 0.487593 0.0132129 0.138399 -0.0536827 -0.311496 -0.0889277 -0.177573 -0.0465511 0.401527 -0.188835 0.0338331 -0.488539 -0.118576 -0.106807 -0.0926993 -0.541991 -0.396698 -0.904539 -0.13031 -0.212209 0.0448515 0.00288283 0.081941 0.203644 -0.179872 0.0726569 -0.112933 0.000482156 0.125257 0.193241 -0.742001 -0.107412 0.155623 -0.151747 -0.0197734 -0.219277 0.182933 -0.150003 YAP-R-E -0.181755 0.0297948 0.106987 -0.272665 0.2726 -0.0502745 0.16051 0.735761 1.39865 0.0879239 -0.164037 -0.501615 0.0741752 0.250221 0.00500413 0.0360644 0.490096 -0.105342 0.421842 0.441784 0.113654 -0.134788 -0.129597 0.0327801 1.16077 0.159809 0.312376 0.48973 0.0518567 -0.0877431 0.189154 0.00801493 -0.155408 0.178229 0.415212 0.331077 -0.345231 0.207328 0.234185 -0.121768 0.121997 0.326315 -0.0967104 YAP-R-V YAP_pS127-R-C YAP_pS127-R-E -0.0903208 0.390504 0.349023 -0.628399 -0.0651403 -1.08267 -0.623544 2.27485 2.02519 0.172973 -0.152726 -1.7246 -0.0108594 0.323982 0.0898068 0.00975597 1.43538 0.171131 0.293005 -0.305912 0.388306 -0.57642 0.270962 0.410978 1.67739 0.635779 0.379154 1.0765 -0.0516575 0.189144 0.445457 0.0819311 -0.262731 0.279662 0.408166 0.95751 -0.243048 -0.111607 0.142374 -0.241404 -0.0367062 -0.0369712 -0.516304 YB-1-R-V -0.333415 0.0633646 -0.325997 -0.209465 0.137108 0.460097 0.289153 -0.192974 -0.189875 -0.193128 -0.0635567 -0.354484 0.163939 -0.258549 0.142958 0.00179943 0.206491 0.300512 0.062809 0.137816 -0.201932 0.227346 0.21079 -0.0502303 0.810186 -0.151487 0.0955194 0.111624 -0.543538 0.0611355 0.0125058 0.23275 -0.246748 -0.0538066 0.403542 0.328745 0.120622 -0.0784391 0.291133 -0.122585 0.0467238 -0.670533 0.260311 YB-1_pS102-R-V 0.133465 0.246832 -0.0132793 0.536759 -0.138827 -0.210319 -0.128921 -0.111936 0.0196132 0.382487 0.0121335 0.0609068 0.0398986 0.100984 -0.145653 0.469625 0.0173465 0.157357 -0.125489 -0.00115197 0.230099 0.0529203 0.874359 0.237116 0.265881 0.0443878 -0.01711 0.000108407 -0.00661275 -0.171772 0.120166 0.549439 0.134328 0.169653 0.0710891 -0.0315161 0.0361828 -0.0508563 0.130167 0.0336914 0.223256 -0.281945 0.0636823 alpha-Catenin-M-V 0.0477289 0.021912 0.361178 0.0586736 -0.00076318 -0.0498851 0.160468 -0.614539 0.0259821 0.184431 -0.0198355 0.172356 0.0763249 -0.158732 0.162633 0.42443 0.265703 0.0787772 -0.0956772 -0.256543 0.203125 0.290129 -0.0267582 -0.522999 0.122595 -0.0813747 beta-Catenin-R-V -0.0464525 0.568983 0.929675 -0.625135 0.104761 1.14692 -0.0194862 -1.21863 -0.0510666 1.14342 0.117784 -2.06795 0.401723 -0.599451 -0.366646 0.259173 -2.4044 0.791026 -0.0955472 -0.28755 -0.510038 -0.266352 -0.159941 0.649835 -1.95923 -1.22859 0.432365 -1.0909 -2.60953 -0.279215 -0.335233 0.599809 -2.84038 -1.88161 1.23914 -1.64553 -0.275266 -1.42677 0.639269 -0.571892 -1.04174 -2.20323 -0.082224 c-Abl-R-V -0.0120259 0.299994 -0.307198 -0.00594595 -0.046057 -0.226563 -0.0458123 0.0826082 0.270215 -0.201986 -0.159018 0.978762 -0.217691 0.0454964 0.1309 -0.0126992 0.436373 -0.0796165 0.156126 0.184908 0.117193 0.110926 -0.240166 0.0141082 0.340903 0.151389 0.132689 0.055805 0.410363 0.0245727 -0.10768 0.0988765 0.50596 -0.0605302 -0.14269 0.491576 -0.15708 -0.0609419 -0.147476 0.160627 0.148162 0.611293 9.24355e-05 c-Jun_pS73-R-C c-Jun_pS73-R-V 0.149701 0.0357493 -0.157037 -0.163344 -0.491253 -0.344311 -0.207172 -0.108374 0.142832 -0.00103658 0.16435 -0.0282929 -0.198308 -0.338266 -0.0807503 -0.173116 -0.0524591 -0.115899 -0.0245387 0.316378 -0.0460594 -0.240833 0.547877 -0.100339 0.304646 -0.269154 -0.0717012 -0.084041 -0.428172 0.197844 -0.0255111 0.150595 -0.184146 -0.218773 0.0544141 -0.219438 0.186058 -0.216447 0.225087 -0.119422 -0.39339 0.0351186 0.198665 c-Kit-R-V -0.340679 -0.149619 0.090678 -0.454927 0.0662655 0.00268753 0.00988937 0.373904 -0.408137 -0.32647 -0.243491 0.0263987 -0.111352 -0.313536 -0.0462193 -0.283664 1.25936 -0.429826 -0.443847 -0.267789 0.197196 0.181837 -0.324848 0.46434 0.0944909 -0.279427 -0.0493422 -0.158157 -0.314029 0.281318 -0.375171 -0.459087 -0.0538818 -0.105332 0.341655 0.850011 -0.229611 0.0471755 -0.241728 -0.244824 0.00738281 0.0742075 -0.0168764 c-Met-M-E -0.112543 -0.144555 -0.0567704 -0.329495 -0.199952 -0.184865 -0.302084 -0.0877081 0.128713 -0.32297 0.00312907 0.543255 -0.0993904 -0.192359 -0.0662986 -0.101006 0.238085 -0.116222 0.00368751 -0.0849594 -0.339644 -0.0195019 0.0812661 -0.052939 1.58717 0.20236 -0.0550898 0.103293 0.429872 0.288557 -0.0682806 -0.0476427 0.606965 0.0975652 -0.165216 0.520971 -0.113445 0.169752 0.00483872 0.0893078 -0.400505 0.226696 0.0135126 c-Met_pY1235-R-C c-Met_pY1235-R-V -0.115148 -0.0528548 -0.0916145 0.0365002 0.132852 0.0729676 0.232014 0.183096 0.0706143 -0.000170008 0.0841825 0.244468 0.0104944 0.201679 0.196076 0.0604991 0.253066 0.0548819 0.170914 0.250895 0.0680789 -0.0326625 0.0967915 -0.090881 0.538786 0.038283 0.0398316 0.00314454 0.213336 -0.0121619 0.0168533 -0.0347719 0.161179 0.0165413 0.0867183 0.180067 -0.0981446 -0.015097 -0.0121553 -0.101287 -0.103629 0.329831 0.0677313 c-Myc-R-C 0.135461 0.01168 -0.0975579 -0.313768 -0.263836 -0.53641 0.44288 0.112528 0.0867115 -0.172746 0.0682608 0.866272 0.0325089 -0.513435 0.0462963 0.136524 0.52765 -0.153989 -0.302188 1.99989 -0.390284 -0.0395589 0.46567 0.538454 0.478176 -0.29944 0.0499438 -0.00365471 0.0356764 -0.0849156 -0.0632812 0.149931 0.203371 -0.116222 -0.0100134 0.0450589 0.283357 -0.134505 0.0592092 -0.0641744 0.544461 0.434272 -0.204023 cIAP-R-V -0.129967 0.172483 0.00472861 0.0273961 0.0309111 0.109505 -0.0814456 0.104076 0.627858 0.292154 -0.232841 -0.260766 -0.0223153 0.465926 0.131239 -0.00179943 -0.415254 -0.0461497 0.265428 -0.0881906 0.0569131 -0.164981 -0.601135 0.289941 -0.431218 0.416044 -0.00153805 0.179697 0.0876833 -0.0441607 -0.0778085 0.00622703 -0.0738939 0.138115 -0.0131102 -0.129075 -0.162298 0.102232 -0.1086 0.0159502 -0.03367 0.32402 0.115288 eEF2-R-C -0.144341 0.0157851 -0.0224559 0.0889036 0.334208 -0.0189139 0.558722 -0.753752 -0.182694 0.467485 0.0422931 -0.843085 0.289937 0.28472 0.123829 0.170285 -0.62386 0.081592 0.110622 0.0428513 -0.121534 0.276676 -0.256037 -0.391575 -1.18785 0.256735 0.213418 0.195684 0.105885 -0.25896 0.135366 0.491854 0.15492 0.144319 0.00431432 -0.514561 -0.0168052 0.219348 0.238084 0.363077 0.161674 0.411385 0.0855063 eEF2-R-V eEF2K-R-V -0.547109 -0.209048 0.20316 0.260506 0.285197 1.4484 1.36246 -0.627746 -0.306076 0.407807 -0.0619004 -0.911221 0.506537 -0.641653 -0.151549 0.211001 -0.771265 0.913782 -0.454957 0.492319 -0.612763 0.879857 0.132681 -0.715276 -0.225945 -0.590034 -0.528253 -0.682656 -1.26226 0.0831414 0.499271 0.0870587 -1.68471 -1.14933 -0.188987 -0.707855 0.325947 -1.21036 -0.497507 -0.335285 -0.420982 -1.43286 0.0438738 eIF4E-R-V -0.0529564 -0.0902623 0.145848 0.231561 -0.0204707 -0.353122 0.29603 0.238336 -0.191029 0.0115094 -0.363842 -0.137146 0.12417 0.109505 0.0823123 0.330932 -0.00508256 0.183525 0.377437 0.313274 0.0937033 0.0264695 -0.517734 -0.0404721 -0.638771 0.23146 -0.0126052 0.0995825 0.407092 -0.0920711 -0.034748 -0.0510526 0.589513 0.389476 -0.180793 -0.180912 -0.140094 0.246606 -0.00305947 -0.147424 -0.00319418 0.700226 0.0724548 eIF4G-R-C 0.0733875 0.0529897 0.151241 0.651015 0.121184 0.473055 1.0296 -0.238971 0.176815 1.11504 0.543485 -1.19084 0.483502 -0.83864 -0.190847 0.322641 -0.658249 1.00762 -0.0445831 0.417377 -0.148307 0.459776 -0.116309 -0.125521 -0.43179 -0.787169 -0.00414733 -0.637202 -2.33917 -0.134085 0.506635 0.275839 -2.91194 -1.75797 0.348075 -1.11684 0.307158 -2.25687 -0.277188 -0.0409766 0.336616 -2.59547 0.315282 mTOR-R-V 0.19119 -0.163728 -0.0269244 -0.242208 0.0673528 0.427475 -0.0757513 -0.270754 -0.0701261 0.301278 0.112888 -0.520764 -0.0391807 0.00856706 -0.237854 0.157557 -0.206154 0.146053 -0.0735996 -0.267897 0.136349 -0.133068 -0.545724 -0.0691084 -1.35007 -0.524266 0.0933055 -0.248704 -0.695357 0.0192794 -0.0310263 0.00456028 -1.04578 -0.643859 0.169313 0.000694543 0.157653 -0.315622 -0.188987 0.00857741 -0.0137995 -1.15147 0.0627997 mTOR_pS2448-R-C 0.313843 0.00553159 -0.150023 0.144346 -0.0532557 -0.138417 -0.354827 0.0489663 -0.182924 -0.147569 0.000527617 0.0209806 -0.512622 -0.159995 -0.223349 -0.388229 0.288763 -0.0184633 0.000127161 -0.30481 0.152013 0.0543538 -0.0540639 -0.0188071 -0.288558 -0.179586 -0.0601076 -0.133133 -0.546849 0.101188 -0.0137893 0.263794 -0.389546 -0.219689 -0.0892988 0.244584 -0.00858409 -0.097611 -0.0289529 0.134471 0.00309596 -0.49786 -0.0435098 p16_INK4a-R-V 0.439307 -0.689329 -0.739877 -1.41698 -0.312209 0.874055 -1.26267 0.110592 -0.0157856 -1.11904 -1.51164 0.991844 -0.49202 1.92507 0.207963 -0.688002 -0.0626705 -1.11952 2.3287 -1.22304 -0.553426 0.195097 0.337463 1.07782 -0.271285 1.13568 -0.651551 1.57933 -0.56846 -0.406482 0.882007 -0.955845 -0.386628 1.23617 -0.13936 -0.305232 1.10833 0.291531 0.424385 0.238533 0.29309 1.67219 -0.52168 p21-R-C p21-R-V 0.271034 -0.342857 0.81272 -0.106474 0.943447 0.306558 0.503367 -0.204089 -0.199221 -0.0128577 -0.106422 0.17959 -1.35546 0.254736 -0.574714 -1.00218 0.120667 0.235414 0.0577879 0.155153 -0.851755 0.379918 0.134407 0.557775 0.300579 0.93905 -0.170567 0.4474 1.44651 0.459211 -0.716297 -0.112902 1.88857 0.744952 -1.32633 0.920109 -0.38679 0.929006 0.407926 -0.213969 -1.1093 0.556477 -0.34113 p27-R-V -0.199598 -0.387405 -0.354245 -0.399128 -0.308852 0.183064 -0.246468 0.000172497 -0.00524494 -0.464612 -0.604125 0.0426342 -0.28327 -0.382195 -0.0192665 -0.248078 0.0459687 -0.211672 -0.471481 -0.291257 0.354527 -0.239075 -0.0958589 0.231557 0.599423 -0.123282 0.148893 -0.239232 -0.228743 0.00670243 0.080837 -0.493491 -0.12443 0.0582705 -0.167172 0.1714 0.0131511 0.0704388 -0.102967 -0.0529934 0.197488 -0.368339 0.100482 p27_pT157-R-C 0.0925836 0.0205826 0.0685838 -0.0171514 -0.0768669 -0.00420705 0.0333318 0.0183778 -0.0525901 -0.164333 -0.045589 0.200281 -0.0236893 -0.0463801 -0.0961736 -0.158158 0.244953 -0.00636522 -0.0108872 0.20052 -0.0934312 -0.0284811 -0.00874764 0.0184626 0.138518 -0.200278 -0.127058 -0.105539 -0.15997 0.137583 0.12704 -0.0585601 -0.392773 -0.131291 0.143646 0.0724157 -0.0238313 -0.247162 -0.0352157 -0.0840783 0.0326097 -0.134558 -0.0199743 p27_pT198-R-V 0.0191673 -0.162893 -0.120918 0.0983762 -0.137299 -0.0527383 0.0927348 0.179578 0.051726 0.0695766 0.03176 0.011625 -0.0910719 -0.429926 0.140403 0.0308167 0.131014 -0.104086 -0.267269 0.391329 0.180056 -0.0368412 0.290889 -0.0520745 0.969361 -0.217676 0.0749356 -0.179358 -0.126562 -0.0711258 -0.000674229 -0.0686272 -0.07071 -0.187956 -0.0118811 0.142866 0.104249 -0.227921 0.245978 -0.106869 0.19651 0.115354 0.0709711 p38-R-V p38_MAPK-R-C p38_MAPK-R-V 0.0135936 0.189973 0.246361 0.252809 0.316561 0.174235 0.128961 0.337587 0.267925 0.397738 0.534267 0.532763 -0.121966 0.510959 0.462163 0.0739498 0.234531 0.368207 0.508203 0.0182349 0.293176 0.0157054 -0.283079 0.304543 -0.494859 0.497479 0.282481 0.257701 0.428868 -0.124921 -0.116833 -0.0612133 0.300151 0.534617 -0.0340999 -0.0423777 0.131934 0.569321 0.0805439 0.700406 0.165032 0.444639 0.128062 p38_pT180_Y182-R-V 0.208293 -0.225346 0.228782 0.121259 0.104866 -1.59698 -0.658256 0.211466 -0.523266 0.885388 0.605508 0.156253 -0.830411 0.210769 -0.625836 -0.584227 0.534062 0.779103 -0.0754123 -0.929382 0.295514 -0.523227 0.160764 -0.0513291 -1.41422 0.510629 -0.413642 0.158933 0.623465 -0.0514923 -0.900827 0.032076 0.876199 0.943792 -0.450548 0.390595 0.348655 0.883325 0.61127 -0.577819 -0.280673 -0.232177 -0.674565 p53-R-C p53-R-E -0.31956 -0.50631 -0.225212 -0.263279 0.171592 -0.0196276 0.0663961 0.891399 -0.183269 -0.333952 0.736204 0.140665 -0.189618 0.669252 -0.0575873 -0.258889 0.484603 -0.190128 0.0797504 -0.00131885 -0.627168 0.386628 -0.260917 -0.410065 0.52468 -0.289042 0.428636 0.484624 -0.0869678 0.080432 0.146588 -0.117842 -0.449812 0.158326 -0.123085 -0.0139385 -0.178636 -0.161386 -0.27621 0.0952593 -0.165633 -0.0916013 -0.192236 p53-R-V p62-LCK-ligand-M-C 0.639362 -0.0502547 0.0221022 0.0123177 1.26972 -0.099719 0.025433 0.287586 0.154846 0.0680463 -0.118395 -0.751776 -0.0552 0.340001 -0.134008 -1.35007 -1.01869 -0.0349062 -0.342465 0.13237 -0.583608 -0.121786 0.344049 0.053403 -0.948151 0.760803 p62-LCK-ligand-M-E 0.755145 0.282373 0.0680417 -0.465804 -0.0815492 -0.00877477 0.136134 -1.15908 -0.796424 -0.518733 -0.157273 0.126645 -0.321082 0.392426 -0.505073 0.1417 -0.104631 p63-R-E p70S6K-R-V 0.00957667 0.256817 0.282295 0.0563489 -0.0107136 0.430999 0.737874 -0.708335 0.0312284 0.674612 0.585282 -0.439846 -0.0392327 0.154485 -0.282734 -0.207399 -0.471247 0.484391 -0.0602828 -0.0959223 0.000390059 0.136776 -0.779834 -0.147047 -1.07588 -0.310934 -0.0123872 -0.125289 -1.79304 -0.366002 0.191566 0.0172939 -1.35943 -0.45161 0.68847 -1.79349 0.423151 -0.553423 -0.0182552 0.131237 -0.182055 -2.57287 -0.0903279 p70S6K_pT389-R-V 0.00355002 -0.0281949 -0.199833 -0.029483 -0.225492 -0.164679 -0.194201 -0.0805628 -0.143941 -0.311951 -0.278318 0.49065 -0.0840822 -0.199025 0.160073 -0.146389 0.132119 -0.153168 -0.337645 0.0746691 -0.120504 -0.201701 0.0382428 -0.326105 0.197068 -0.0788472 0.0569276 -0.202874 0.00661275 0.00467499 -0.131763 -0.158381 -0.34011 -0.00570902 -0.0598378 0.190342 0.030662 -0.0751015 -0.186127 -0.25196 0.0537065 0.0719559 -0.17222 p90RSK-R-C -0.0775564 -0.00493441 0.417743 0.208661 0.140039 0.496085 0.23806 -0.283638 0.0227598 0.390162 -0.254475 0.289271 0.520452 0.152725 -0.0269939 0.488848 -0.167755 0.169138 0.578867 0.580525 -0.00859491 0.24841 0.0522834 0.245174 -0.600907 -0.420792 0.0988617 -0.0982006 0.111829 -0.150657 0.0989562 0.0663718 -0.20704 -0.359745 0.130154 -0.179654 0.230431 0.335343 -0.138494 0.202422 0.100769 0.0597317 0.0152931 p90RSK_pT359_S363-R-C 0.156032 0.332695 -0.0561989 0.318438 -0.0236059 0.112019 0.071128 0.177095 -0.0401811 0.176165 -0.1334 0.409355 -0.337541 -0.0512822 0.194592 -0.122495 0.520689 -0.125686 0.152456 0.32678 -0.0455301 -0.0333452 0.600308 0.333658 0.498497 -0.215641 0.160916 -0.0981386 0.0242446 0.162159 0.129437 0.367256 -0.217975 0.0737083 -0.0617799 0.289015 0.0481179 0.0712144 -0.0392584 0.097029 0.140854 0.0770941 0.124069