"Gene Name"	"Array data file names"	"Composite Element Ref"	"Antibody.validation.status"	"Antibody.Origin"	"Antibody.Source..Company."	"Catalog.Number"	"Protein.function.and.regulatory.pathways"
"YWHAB"	"14-3-3_beta-R-V_GBL9017425.txt"	"14-3-3_beta-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"sc-628"	"14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints"
"YWHAE"	"14-3-3_epsilon-M-C_GBL9017330.txt"	"14-3-3_epsilon-M-C"	"Use with Caution"	"Mouse"	"Santa Cruz"	"sc-23957"	"14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints"
"YWHAZ"	"14-3-3_zeta-R-V_GBL9017780.txt"	"14-3-3_zeta-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"sc-1019"	"14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints"
"EIF4EBP1"	"4E-BP1-R-V_GBL9017211.txt"	"4E-BP1-R-V"	"Validated"	"Rabbit"	"CST"	"9452"	"Involves in protein translation. Regulated by PI3K/AKT/mTOR pathway"
"EIF4EBP1"	"4E-BP1_pS65-R-V_GBL9017210.txt"	"4E-BP1_pS65-R-V"	"Validated"	"Rabbit"	"CST"	"9456"	"Involves in protein translation. Regulated by PI3K/AKT/mTOR pathway"
"EIF4EBP1"	"4E-BP1_pT37_T46-R-V_GBL9017379.txt"	"4E-BP1_pT37_T46-R-V"	"Validated"	"Rabbit"	"CST"	"9459"	"Involves in protein translation. Regulated by PI3K/AKT/mTOR pathway"
"EIF4EBP1"	"4E-BP1_pT70-R-C_GBL9017380.txt"	"4E-BP1_pT70-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9455"	"Involved in protein translation, Regulated my PI3K/AKT/mTOR pathway"
"TP53BP1"	"53BP1-R-C_GBL9017212.txt"	"53BP1-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"4937"	"Identified as a p53 binding partner that could enhance the transcriptional activity of p53., Also involves in DNA repair signaling"
"ACACA"	"ACC1-R-C_GBL9017214.txt"	"ACC1-R-C"	"Under Evaluation"	"Rabbit"	"Epitomics"	"1768-1"	"Key enzyme in the biosynthesis and oxidation of fatty acids. Involved in energy homeostasis regulation"
"ACACA ACACB"	"ACC_pS79-R-V_GBL9017213.txt"	"ACC_pS79-R-V"	"Validated"	"Rabbit"	"CST"	"3661"	"Key enzyme in the biosynthesis and oxidation of fatty acids. Involved in energy homeostasis regulation"
"TUBA1B"	"Acetyl-a-Tubulin-Lys40-R-E_GBL9017778.txt"	"Acetyl-a-Tubulin-Lys40-R-E"	"Under Evaluation"	"Rabbit"	"CST"	"5335"	"The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Acetylation of _-tubulin at Lys40 is required for dynamic cell shape remodeling, cell motility, tubulin stability and terminal branching of cortical neurons"
"ACVRL1"	"ACVRL1-R-C_GBL9017427.txt"	"ACVRL1-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"2940-1"	"TNF beta superfamily"
"AKT1 AKT2 AKT3"	"Akt-R-V_GBL9017215.txt"	"Akt-R-V"	"Validated"	"Rabbit"	"CST"	"9272"	"PI3K/AKT/mTOR pathway"
"AKT1 AKT2 AKT3"	"Akt_pS473-R-V_GBL9017216.txt"	"Akt_pS473-R-V"	"Validated"	"Rabbit"	"CST"	"9271"	"PI3K/AKT/mTOR pathway"
"AKT1 AKT2 AKT3"	"Akt_pT308-R-V_GBL9017217.txt"	"Akt_pT308-R-V"	"Validated"	"Rabbit"	"CST"	"9275"	"PI3K/AKT/mTOR pathway"
"PRKAA1"	"AMPK_alpha-R-C_GBL9017218.txt"	"AMPK_alpha-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2532"	"Involved in energy homeostasis regulation"
"PRKAA1"	"AMPK_pT172-R-V_GBL9017219.txt"	"AMPK_pT172-R-V"	"Validated"	"Rabbit"	"CST"	"2535"	"Involved in energy homeostasis regulation"
"ANXA1"	"Annexin-1-M-E_GBL9017801.txt"	"Annexin-1-M-E"	"Under Evaluation"	"Mouse"	"BD Transduction"	"610066"	"Apoptosis"
"ANXA7"	"Annexin_VII-M-V_GBL9017770.txt"	"Annexin_VII-M-V"	"Validated"	"Mouse"	"BD Biosciences"	"610668"	"Apoptosis"
"AR"	"AR-R-V_GBL9017221.txt"	"AR-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1852-1"	"Androgen receptor (AR). Transcription Factor"
"ARAF"	"A-Raf_pS299-R-C_GBL9017435.txt"	"A-Raf_pS299-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4431"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"DIRAS3"	"ARHI-M-E_GBL9017428.txt"	"ARHI-M-E"	"Under Evaluation"	"Mouse"	"Dr. Robert C Bast Jr."	"Customer made"	"A member of the ras superfamily, Expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers."
"ARID1A"	"ARID1A-M-V_GBL9017417.txt"	"ARID1A-M-V"	"Validated"	"Mouse"	"Abgent"	"AT1188a"	"Involves in PI3K/PTEN signaling"
"ASNS"	"ASNS-R-E_GBL9017432.txt"	"ASNS-R-E"	"Validated"	"Rabbit"	"Sigma"	"HPA029318"	"The protein encoded by ASNS gene is involved in the synthesis of asparagine. "
"ATM"	"ATM-R-C_GBL9017381.txt"	"ATM-R-C"	"Under Evaluation"	"Rabbit"	"Abcam"	"ab32420"	"Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. "
"AXL"	"Axl-R-V_GBL9017784.txt"	"Axl-R-V"	""	""	""	""	""
"BAD"	"Bad_pS112-R-V_GBL9017764.txt"	"Bad_pS112-R-V"	"Validated"	"Rabbit"	"CST"	"9291"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein "
"BAK1"	"Bak-R-C_GBL9017222.txt"	"Bak-R-C"	"Under Evaluation"	"Rabbit"	"Epitomics"	"1542-1"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein "
"BAP1"	"Bap1-c-4-M-V_GBL9017437.txt"	"Bap1-c-4-M-V"	"Ender Evaluation"	"Rabbit"	"Alomine"	"APC-125"	"BAP1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization"
"BAX"	"Bax-R-V_GBL9017223.txt"	"Bax-R-V"	"Validated"	"Rabbit"	"CST"	"2772"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein "
"BCL2"	"Bcl-2-M-V_GBL9017332.txt"	"Bcl-2-M-V"	"Validated"	"Mouse"	"Dako"	"Dako M0887"	"Anti-apoptotic protein, Oncoprotein"
"BCL2L1"	"Bcl-xL-R-V_GBL9017225.txt"	"Bcl-xL-R-V"	"Validated"	"Rabbit"	"CST"	"2762"	"Bcl-2 interacting mediator of cell death, anti-apoptotic protein "
"BECN1"	"Beclin-G-V_GBL9017376.txt"	"Beclin-G-V"	"Use with Caution"	"Goat"	"Santa Cruz"	"sc-10086"	"BECN1 (Beclin 1) is a coiled-coil protein that has been implicated as an inhibitor of tumorigenesis. BECN1, which associates with Bcl-2, plays a significant role in autophagy."
"CTNNB1"	"beta-Catenin-R-V_GBL9017234.txt"	"beta-Catenin-R-V"	"Validated"	"Rabbit"	"CST"	"9562"	"Downstream effector in the Wnt signaling pathway"
"BID"	"Bid-R-C_GBL9017226.txt"	"Bid-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1008-1"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein belonging to the BH3-interaction protein"
"BCL2L11"	"Bim-R-V_GBL9017227.txt"	"Bim-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1036-1"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein belonging to the BH3-interaction protein"
"BRAF"	"B-Raf-M-E_GBL9017350.txt"	"B-Raf-M-E"	"Use with Caution"	"Mouse"	"Santa Cruz"	"sc-5284"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"BRCA2"	"BRCA2-R-C_GBL9017438.txt"	"BRCA2-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9012"	"The breast cancer susceptibility protein BRCA2 has roles in multiple processes related to DNA damage, repair, cell cycle progression, transcription, ubiquitination, and apoptosis"
"BRD4"	"BRD4-R-V_GBL9017787.txt"	"BRD4-R-V"	""	""	""	""	""
"CASP7"	"Caspase-7_cleavedD198-R-C_GBL9017232.txt"	"Caspase-7_cleavedD198-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9491"	"A major contributor to the execution of apoptosis"
"CASP8"	"Caspase-8-M-C_GBL9017333.txt"	"Caspase-8-M-C"	"**Used for QC**"	"Mouse"	"CST"	"9746"	"Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10. Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7. Caspase-3 ultimately elicits the morphological hallmarks of apoptosis, including DNA fragmentation and cell shrinkage."
"CAV1"	"Caveolin-1-R-V_GBL9017235.txt"	"Caveolin-1-R-V"	"Validated"	"Rabbit"	"CST"	"3238"	"One of the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Interact with multiple signaling molecules such as G_ subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases, and eNOS"
"MS4A1"	"CD20-R-C_GBL9017382.txt"	"CD20-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1632"	"Human B lymphocyte surfacr marker"
"PECAM1"	"CD31-M-V_GBL9017335.txt"	"CD31-M-V"	"Validated"	"Mouse"	"Dako"	"M0823"	"Endothelia cell marker"
"ITGA2"	"CD49b-M-V_GBL9017403.txt"	"CD49b-M-V"	"Validated"	"Mouse"	"BD"	"611016"	"Integrin"
"CDK1"	"CDK1-R-V_GBL9017236.txt"	"CDK1-R-V"	"Validated"	"Rabbit"	"CST"	"9112"	"Involved in the regulation of the entry of eukaryotic cells into mitosis"
"CDK1"	"CDK1_pY15-R-C_GBL9017808.txt"	"CDK1_pY15-R-C"	""	""	""	""	""
"CHEK1"	"Chk1-R-C_GBL9017237.txt"	"Chk1-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2345"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"CHEK1"	"Chk1_pS345-R-C_GBL9017238.txt"	"Chk1_pS345-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2348"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"CHEK2"	"Chk2-M-C_GBL9017336.txt"	"Chk2-M-C"	"Under Evaluation"	"Mouse"	"CST"	"3440"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"CHEK2"	"Chk2_pT68-R-C_GBL9017239.txt"	"Chk2_pT68-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2197"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"BIRC2 "	"cIAP-R-V_GBL90172401.txt"	"cIAP-R-V"	"Use with Caution"	"Rabbit"	"Millipore"	"07-759"	"Apoptosis suppressor"
"JUN"	"c-Jun_pS73-R-C_GBL9017271.txt"	"c-Jun_pS73-R-C"	"Validated"	"Rabbit"	"CST"	"9164"	"MAPK pathway, A component of the transcription factor activator protein-1 (AP-1), Regulates cell proliferation, differentiation, and apoptosis, as well as transformation, invasion and metastasis"
"KIT"	"c-Kit-R-V_GBL9017419.txt"	"c-Kit-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1522"	"Tyrosine Kinase Receptor"
"CLDN7"	"Claudin-7-R-V_GBL9017241.txt"	"Claudin-7-R-V"	"Validated"	"Rabbit"	"Novus"	"NB100-91714"	"Claudins  make up tight junction strands."
"MET"	"c-Met-M-C_GBL9017342.txt"	"c-Met-M-C"	"**Used for QC**"	"Mouse"	"CST"	"3127"	"Met, a high affinity tyrosine kinase receptor for hepatocyte growth factor (HGF, also known as scatter factor) is a disulfide-linked heterodimer made of 45 kDa ?- and 145 kDa ?-subunits. The ?-subunit and the amino-terminal region of the ?-subunit form the extracellular domain. The remainder of the ?-chain spans the plasma membrane and contains a cytoplasmic region with tyrosine kinase activity. Interaction of Met with HGF results in autophosphorylation at multiple tyrosines, which recruit several downstream signaling components, including Gab1, c-Cbl, and PI3 kinase. These fundamental events are important for all of the biological functions involving Met kinase activity. The addition of a phosphate at cytoplasmic Tyr1003 is essential for Met protein ubiquitination and degradation. Phosphorylation at Tyr1234/1235 in the Met kinase domain is critical for kinase activation. Phosphorylation at Tyr1349 in the Met cytoplasmic domain provides a direct binding site for Gab1. Research studies have shown that altered Met levels and/or tyrosine kinase activities are found in several types of tumors, including renal, colon, and breast. Thus, investigators have concluded that Met is an attractive potential cancer therapeutic and diagnostic target."
"MET"	"c-Met_pY1235-R-C_GBL9017276.txt"	"c-Met_pY1235-R-C"	"Validated"	"Rabbit"	"CST"	"3129"	"Tyrosine kinase receptor for hepatocyte growth factor"
"MYC"	"c-Myc-R-C_GBL9017279.txt"	"c-Myc-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9402"	"Members of the Myc/Max/Mad network function as transcriptional regulators invlolving in proliferation, differentiation and apoptosis"
"COL6A1"	"Collagen_VI-R-V_GBL9017242.txt"	"Collagen_VI-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"SC-20649"	"Collagens are fibrous, extracellular matrix proteins play a role in cell adhesion, important for maintaining normal tissue architecture and function."
"RAF1"	"C-Raf-R-V_GBL9017305.txt"	"C-Raf-R-V"	"Validated"	"Rabbit"	"Millipore"	"05-739"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"RAF1"	"C-Raf_pS338-R-C_GBL9017364.txt"	"C-Raf_pS338-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"9427"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"CCNB1"	"Cyclin_B1-R-V_GBL9017244.txt"	"Cyclin_B1-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1495-1"	"Cyclin B1 regulates mitosis. Cyclin B1 levels rise during S phase and G2, and peak at mitosis. "
"CCND1"	"Cyclin_D1-R-V_GBL9017245.txt"	"Cyclin_D1-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"SC-718"	"Cyclin D corresponds to a putative human oncogene. It regulates phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors"
"CCNE1"	"Cyclin_E1-M-V_GBL9017337.txt"	"Cyclin_E1-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"SC-247"	"Cyclin E has been found to be associated with the transcription factor E2F in a temporally regulated manner. The cyclin E/E2F complex is detected primarily during the G1 phase of the cell cycle and decreases as cells enter S phase. E2F is known to be a critical transcription factor for expression of several S phase specific proteins."
"CCNE2"	"Cyclin_E2-R-C_GBL9017383.txt"	"Cyclin_E2-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1142"	"Controls cell cycle at late G1 and early S phase"
"PARK7"	"DJ-1-R-C_GBL9017246.txt"	"DJ-1-R-C"	"Validated"	"Rabbit"	"Abcam"	"ab76008"	"May involved in regulation of PTEN expression"
"DVL3"	"Dvl3-R-V_GBL9017247.txt"	"Dvl3-R-V"	"Validated"	"Rabbit"	"CST"	"3218"	"Intermediates of Wnt signaling pathways"
"CDH1"	"E-Cadherin-R-V_GBL9017228.txt"	"E-Cadherin-R-V"	"Validated"	"Rabbit"	"CST"	"4065"	"A member of transmembrane glycoprotein superfamily, Mediate calcium-dependent cell-cell adhesion and normal tissue development. "
"EEF2"	"eEF2-R-V_GBL9017248.txt"	"eEF2-R-V"	"Use with Caution"	"Rabbit"	"CST"	"2332"	"Eukaryotic elongation factor 2 (eEF2) catalyzes the translocation of peptidyl-tRNA from the A site to the P site on the ribosome. Insulin induces rapid dephosphorylation of eEF2 through mTOR signaling."
"EEF2K"	"eEF2K-R-V_GBL9017249.txt"	"eEF2K-R-V"	"Validated"	"Rabbit"	"CST"	"3692"	"Eukaryotic elongation factor 2 kinase (eEF2k) phosphorylates and inactivates eEF2, resulting in the inhibition of peptide-chain elongation.p90RSK and p70 S6 kinase phosphorylate and inactivate eEF2k."
"EGFR"	"EGFR-R-V_GBL9017434.txt"	"EGFR-R-V"	"Validated"	"Rabbit"	"CST"	"2232"	"Epidermal growth factor receptor (EGFR), Tyrosine Kinase Receptor"
"EGFR"	"EGFR_pY1068-R-V_GBL9017251.txt"	"EGFR_pY1068-R-V"	"Use with Caution"	"Rabbit"	"CST"	"2234"	"Epidermal growth factor receptor (EGFR), Tyrosine Kinase Receptor"
"EGFR"	"EGFR_pY1173-R-C_GBL9017252.txt"	"EGFR_pY1173-R-C"	"Validated"	"Rabbit"	"Epitomics"	"1124"	"Epidermal growth factor receptor (EGFR), Tyrosine Kinase Receptor"
"EIF4E"	"eIF4E-R-V_GBL9017254.txt"	"eIF4E-R-V"	"Valid"	"Rabbit"	"CST"	"9742"	"Eukaryotic initiation factor 4E (eIF4E) binds to the mRNA cap structure to mediate the initiation of translation (1,2). eIF4E interacts with eIF4G, a scaffold protein that promotes assembly of eIF4E and eIF4A into the eIF4F complex (2). eIF4B is thought to assist the eIF4F complex in translation initiation. Upon activation by mitogenic and/or stress stimuli mediated by Erk and p38 MAPK, Mnk1 phosphorylates eIF4E at Ser209 in vivo (3,4). Two Erk and p38 MAPK phosphorylation sites in mouse Mnk1 (Thr197 and Thr202) are essential for Mnk1 kinase activity (3). The carboxy-terminal region of eIF4G also contains serum-stimulated phosphorylation sites, including Ser1108, Ser1148, and Ser1192 (5). Phosphorylation at these sites is blocked by the PI3 kinase inhibitor LY294002 and by the FRAP/mTOR inhibitor rapamycin."
"EIF4G1"	"eIF4G-R-C_GBL9017439.txt"	"eIF4G-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2498"	"Translation initiation factor"
"ESR1"	"ER-alpha-R-V_GBL9017255.txt"	"ER-alpha-R-V"	"Validated"	"Rabbit"	"Lab Vision"	"RM-9101-S"	"Estrogen receptor, Transcription Factor"
"ESR1"	"ER-alpha_pS118-R-V_GBL9017256.txt"	"ER-alpha_pS118-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1091-1"	"Estrogen receptor, Transcription Factor"
"ERCC1"	"ERCC1-M-C_GBL9017338.txt"	"ERCC1-M-C"	"**Used for QC**"	"Mouse"	"Lab Vision"	"MS-671-PO"	"Involved in DNA repaire"
"MAPK1"	"ERK2-R-E_GBL9017414.txt"	"ERK2-R-E"	"Under Evaluation"	"Rabbit"	"Santa Cruz"	"sc-154"	"Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42)."
"ETS1"	"ETS-1-R-V_GBL9017761.txt"	"ETS-1-R-V"	"Validated"	"Rabbit"	"BethYl"	"A303-501A"	"Ets-1 is a member of the ETS family of transcription factors"
"FASN"	"FASN-R-V_GBL9017440.txt"	"FASN-R-V"	"Validated"	"Rabbit"	"CST"	"3180"	"Fatty acid synthase (FASN) catalyzes the synthesis of long-chain fatty acids from acetyl-CoA and malonyl-CoA. Indicated as a poor prognosis in breast and prostate cancer. "
"FN1"	"Fibronectin-R-C_GBL9017408.txt"	"Fibronectin-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1574-1"	"Involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape"
"FOXM1"	"FoxM1-R-V_GBL9017441.txt"	"FoxM1-R-V"	"Validated"	"Rabbit"	"CST"	"5436"	"A forkhead box family transcription factor that regulates a number of genes throughout the cell cycle to help control DNA replication, mitosis and cell proliferation"
"FOXO3"	"FOXO3a-R-C_GBL9017259.txt"	"FOXO3a-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9467"	"Transcription Factor, involved in tyrosin kinase receptor and PI3K/AKT pathway"
"FOXO3"	"FOXO3a_pS318_S321-R-C_GBL9017260.txt"	"FOXO3a_pS318_S321-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9465"	"Transcription Factor, involved in tyrosin kinase receptor and PI3K/AKT pathway"
"G6PD"	"G6PD-M-V_GBL9017771.txt"	"G6PD-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-373887"	"Plays an important role in the pentose phosphate pathway"
"GAB2"	"GAB2-R-V_GBL9017261.txt"	"GAB2-R-V"	"Validated"	"Rabbit"	"CST"	"3239"	"Adaptor proteins recruited by a wide variety of receptor tyrosine kinases (RTKs) such as EGFR, HGFR, insulin receptor, cytokine receptor and B cell antigen receptors"
"GAPDH"	"GAPDH-M-C_GBL9017772.txt"	"GAPDH-M-C"	"Use with Caution"	"Mouse"	"Ambion"	"AM4300"	"Glyceraldehyde 3-phosphate dehydrogenase"
"GATA3"	"GATA3-M-V_GBL9017415.txt"	"GATA3-M-V"	"Validated"	"Mouse"	"BD Biosciences"	"558686"	"Transcription factor"
"GATA6"	"GATA6-R-E_GBL9017786.txt"	"GATA6-R-E"	""	""	""	""	""
"GSK3A GSK3B"	"GSK3-alpha-beta-M-V_GBL9017369.txt"	"GSK3-alpha-beta-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"SC-7291"	"An enzyme that regulates glycogen synthesis in response to insulin, Also involved in Wnt signaling"
"GSK3A GSK3B"	"GSK3-alpha-beta_pS21_S9-R-V_GBL9017263.txt"	"GSK3-alpha-beta_pS21_S9-R-V"	"Validated"	"Rabbit"	"CST"	"9331"	"An enzyme that regulates glycogen synthesis in response to insulin, Also involved in Wnt signaling"
"GSK3A GSK3B"	"GSK3_pS9-R-V_GBL9017262.txt"	"GSK3_pS9-R-V"	"Validated"	"Rabbit"	"CST"	"9336"	"An enzyme that regulates glycogen synthesis in response to insulin, Also involved in Wnt signaling"
"ERBB2"	"HER2-M-V_GBL9017370.txt"	"HER2-M-V"	"Validated"	"Mouse"	"Lab Vision"	"MS-325-P1"	"The ErbB-2 proto-oncogene product"
"ERBB2"	"HER2_pY1248-R-E_GBL9017388.txt"	"HER2_pY1248-R-E"	"Use with Caution"	"Rabbit"	"Upstate (Millipore)"	"06-229"	"The ErbB-2 proto-oncogene product"
"ERBB3"	"HER3-R-V_GBL9017265.txt"	"HER3-R-V"	"Validated"	"Mouse"	"Lab Vision"	"MS-201-P1ABX"	"A member of the ErbB receptor protein tyrosine kinase family, but it lacks tyrosine kinase activity"
"ERBB3"	"HER3_pY1289-R-C_GBL9017266.txt"	"HER3_pY1289-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4791"	"A member of the ErbB receptor protein tyrosine kinase family, but it lacks tyrosine kinase activity"
"NRG1"	"Heregulin-R-V_GBL9017442.txt"	"Heregulin-R-V"	"Validated"	"Rabbit"	"CST"	"2573"	"A soluble growth factor synthesized as a transmembrane precursor molecule involved in HRG-ErbB3/ErbB4 signaling to regulate cell proliferation, differentiation, invasion, and survival of both normal and malignant tissues"
"HSPA1A"	"HSP70-R-C_GBL9017384.txt"	"HSP70-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4872"	"A molecular chaperone expressed constitutively under normal conditions to maintain protein homeostasis and are induced upon environmental stress"
"IGFBP2"	"IGFBP2-R-V_GBL9017268.txt"	"IGFBP2-R-V"	"Validated"	"Rabbit"	"CST"	"3922"	"Insulin-like growth factor-binding proteins (IGFBPs), Tyrosine kinase receptor"
"INPP4B"	"INPP4B-G-C_GBL9017377.txt"	"INPP4B-G-C"	"Under Evaluation"	"Goat"	"Santa Cruz"	"SC-12318"	"The inositol polyphosphate 4-phosphatases catalyze the hydrolysis of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate."
"IRS1"	"IRS1-R-V_GBL9017269.txt"	"IRS1-R-V"	"Validated"	"Rabbit"	"Upstate (Millipore)"	"06-248"	"Insulin receptor substrate (IRS) molecules are key mediators in insulin signaling and play a central role in maintaining basic cellular functions such as growth, survival, and metabolism. Involves in PI3K pathway."
"MAPK9"	"JNK2-R-C_GBL9017270.txt"	"JNK2-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4672"	"The stress-activated protein kinase, Belong to MAPK pathway (MKK4/7)"
"MAPK8"	"JNK_pT183_pY185-R-V_GBL9017354.txt"	"JNK_pT183_pY185-R-V"	"Validated"	"Rabbit"	"CST"	"4668"	"The stress-activated protein kinase, Belong to MAPK pathway (MKK4/7)"
"XRCC5"	"Ku80-R-C_GBL9017392.txt"	"Ku80-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2180"	"Functions as the DNA-binding regulatory component of DNA-dependent protein kinase (DNA-PK) involving in DNA repaire"
"LCK"	"Lck-R-V_GBL9017389.txt"	"Lck-R-V"	"Validated"	"Rabbit"	"CST"	"2752"	"A member of Src family of protein tyrosine kinases"
"STK11"	"LKB1-M-E_GBL9017416.txt"	"LKB1-M-E"	"Under Evaluation"	"Mouse"	"Abcam"	"ab15095"	"Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor."
"MAPK1 MAPK3"	"MAPK_pT202_Y204-R-V_GBL9017273.txt"	"MAPK_pT202_Y204-R-V"	"Validated"	"Rabbit"	"CST"	"4377"	"MAPK pathway (Mitogen-activated protein kinases), Regulates cell growth and differentiation"
"MAP2K1"	"MEK1-R-V_GBL9017274.txt"	"MEK1-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1235-1"	"MAPK pathway (Mitogen-activated protein kinases), Regulates cell growth and differentiation"
"MAP2K1"	"MEK1_pS217_S221-R-V_GBL9017358.txt"	"MEK1_pS217_S221-R-V"	"Validated"	"Rabbit"	"CST"	"9154"	"MAPK pathway (Mitogen-activated protein kinases), Regulates cell growth and differentiation"
"ERRFI1"	"MIG-6-M-V_GBL9017343.txt"	"MIG-6-M-V"	"Validated"	"Mouse"	"Sigma"	"WH0054206M1"	"ERRFI1 (MIG6) is a cytoplasmic protein whose expression is upregulated with cell growth "
"MRE11A"	"Mre11-R-C_GBL9017277.txt"	"Mre11-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4847"	"A central part of a multisubunit nuclease composed of Mre11, Rad50 and Nbs1 (MRN), Plays a critical role in sensing, processing and repairing DNA double strand breaks"
"MSH2"	"MSH2-M-C_GBL9017344.txt"	"MSH2-M-C"	"Validated"	"Mouse"	"CST"	"2850"	"MSH2 (MutS homologue 2) forms the hMutS-_ dimer with MSH6 and is an essential component of the mismatch DNA repair process. "
"MSH6"	"MSH6-R-C_GBL9017359.txt"	"MSH6-R-C"	"Use with Caution"	"Rabbit"	"Novus Biologicals"	"22030002"	"MSH6 is a mismatch-repair protein. It forms the hMutS-_ dimer with MSH2 and is an essential component of the mismatch DNA repair process. It plays a role in tumor suppression."
"MTOR"	"mTOR-R-V_GBL9017385.txt"	"mTOR-R-V"	"Validated"	"Rabbit"	"CST"	"2983"	"The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase, a major component of PI3K/AKT pathway"
"MTOR"	"mTOR_pS2448-R-C_GBL9017329.txt"	"mTOR_pS2448-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2971"	"The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase, a major component of PI3K/AKT pathway"
"MYH11"	"MYH11-R-V_GBL9017423.txt"	"MYH11-R-V"	"Validated"	"Rabbit"	"SDI / Novus"	"21370002"	"Myosin II forms bipolar filaments that interact with actin filaments to produce contraction."
"MYH9"	"Myosin-IIa-R-C_GBL9017785.txt"	"Myosin-IIa-R-C"	""	""	""	""	""
"MYH9"	"Myosin-IIa_pS1943-R-V_GBL9017424.txt"	"Myosin-IIa_pS1943-R-V"	"Validated"	"Rabbit"	"CST"	"5026"	"Non muscle myosin is an actin-based motor protein essential to cell motility, cell division, migration, adhesion, and polarity"
"CDH2"	"N-Cadherin-R-V_GBL9017229.txt"	"N-Cadherin-R-V"	"Validated"	"Rabbit"	"CST"	"4061"	"A member of transmembrane glycoprotein superfamily, Mediate calcium-dependent cell-cell adhesion and normal tissue development. "
"NDRG1"	"NDRG1_pT346-R-V_GBL9017767.txt"	"NDRG1_pT346-R-V"	"Validated"	"Rabbit"	"CST"	"3217"	"A member of the NDRG family functions in growth, differentiation, and cell survival "
"NF2"	"NF2-R-C_GBL9017281.txt"	"NF2-R-C"	"Use with Caution"	"Rabbit"	"SDI"	"2271.00.02"	"Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals"
"NFKB1"	"NF-kB-p65_pS536-R-C_GBL9017280.txt"	"NF-kB-p65_pS536-R-C"	"Use with Caution"	"Rabbit"	"CST"	"3033"	"Transcription factors of the nuclear factor _ B (NF-_B)/Rel family play a pivotal role in inflammatory and immune responses "
"NOTCH1"	"Notch1-R-V_GBL9017282.txt"	"Notch1-R-V"	"Validated"	"Rabbit"	"CST"	"3268"	"A member of transmembrane receptor family that play important roles in development and the determination of cell fate "
"NRAS"	"N-Ras-M-V_GBL9017773.txt"	"N-Ras-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-31"	"The three Ras oncogenes, H-Ras, K-Ras and N-Ras, encode proteins with GTP/GDP binding and GTPase activity. Activates MAPK pathway."
"CDKN1A"	"p21-R-C_GBL9017284.txt"	"p21-R-C"	"Validated"	"Rabbit"	"Santa Cruz"	"SC-397"	"p21 is a potent, tight-binding inhibitor of Cdks and can inhibit the phosphorylation of Rb by cyclin A-Cdk 2, cyclin E-Cdk2, cyclin D1-Cdk4 and cyclin D2-Cdk4 complexes. Involves in p53 pathway and induces cell cycle arrest."
"CDKN1B"	"p27-R-V_GBL9017285.txt"	"p27-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1591-1"	"Regulates cell cycle arrest at G1 phase"
"CDKN1B"	"p27_pT157-R-C_GBL9017286.txt"	"p27_pT157-R-C"	"Use with Caution"	"Rabbit"	"R&D"	"AF1555"	"Regulates cell cycle arrest at G1 phase"
"CDKN1B"	"p27_pT198-R-V_GBL9017287.txt"	"p27_pT198-R-V"	"Validated"	"Rabbit"	"Abcam"	"ab64949"	"Involved in cell cycle arrest at G1 phase."
"MAPK14"	"p38_MAPK-R-C_GBL9017288.txt"	"p38_MAPK-R-C"	"Validated"	"Rabbit"	"CST"	"9212"	" A member of MAPKs. MKK3, MKK6, and SEK phosphorylate and activate p38 MAPK"
"MAPK14"	"p38_pT180_Y182-R-V_GBL9017289.txt"	"p38_pT180_Y182-R-V"	"Validated"	"Rabbit"	"CST"	"9211"	" A member of MAPKs. MKK3, MKK6, and SEK phosphorylate and activate p38 MAPK"
"TP53"	"p53-R-V_GBL9017360.txt"	"p53-R-V"	"Under Evaluation"	"Rabbit"	"CST"	"9282"	"Tumor suppressor and Transcription Factor, Regulates cell cycle arrest and apoptosis and DNA repair "
"SQSTM1"	"p62-LCK-ligand-M-E_GBL9017777.txt"	"p62-LCK-ligand-M-E"	"Under Evaluation"	"Mouse"	"BD Transduction Lab"	"610833"	"p62 lck ligand (zeta-interacting protein (ZIP)) is a cytoplasmic protein that binds to the SH2 domain of lck. It interacts with PKC_.."
"RPS6KB1"	"p70S6K-R-V_GBL9017291.txt"	"p70S6K-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1494-1"	"Mitogen-activated Ser/Thr protein kinase, Involved in PI3K, MAPK and PKC pathways"
"RPS6KB1"	"p70S6K_pT389-R-V_GBL9017292.txt"	"p70S6K_pT389-R-V"	"Validated"	"Rabbit"	"CST"	"9205"	"Mitogen-activated Ser/Thr protein kinase, Involved in PI3K, MAPK and PKC pathways"
"RPS6KA1"	"p90RSK-R-C_GBL9017446.txt"	"p90RSK-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9347"	"The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases involving in MAPK and PI3K signaling"
"RPS6KA1"	"p90RSK_pT359_S363-R-C_GBL9017293.txt"	"p90RSK_pT359_S363-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9344"	"The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases involving in MAPK and PI3K signaling"
"SERPINE1"	"PAI-1-M-E_GBL9017430.txt"	"PAI-1-M-E"	"Under Evaluation"	"Mouse"	"BD Biosciences"	"612024"	"PAI-1 is a glycoprotein involves in tissue plasminogen activator (tPA) and urokinase PA (uPA) signaling"
"PARP1"	"PARP_cleaved-M-C_GBL9017345.txt"	"PARP_cleaved-M-C"	"**Used for QC**"	"Mouse"	"CST"	"9546"	"PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress. This protein can be cleaved by many ICE-like caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. In human PARP, the cleavage occurs between Asp214 and Gly215, which separates the PARP amino-terminal DNA binding domain (24 kDa) from the carboxy-terminal catalytic domain (89 kDa). PARP helps cells to maintain their viability; cleavage of PARP facilitates cellular disassembly and serves as a marker of cells undergoing apoptosis."
"PXN"	"Paxillin-R-V_GBL9017294.txt"	"Paxillin-R-V"	"Use with Caution"	"Rabbit"	"Epitomics"	"1500-1"	"Involved in actin-membrane attachment, Regulates integrin signaling"
"CDH3"	"P-Cadherin-R-C_GBL9017230.txt"	"P-Cadherin-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2130"	"A member of transmembrane glycoprotein superfamily, Mediate calcium-dependent cell-cell adhesion and normal tissue development. "
"PCNA"	"PCNA-M-V_GBL9017346.txt"	"PCNA-M-V"	"Use with Caution"	"Mouse"	"Abcam"	"ab29"	"Involves in DNA repair"
"PDCD4"	"PDCD4-R-C_GBL9017447.txt"	"PDCD4-R-C"	"Use with Caution"	"Rabbit"	"Rockland"	"600-401-965"	"Pdcd4 directly inhibits the helicase activity of eukaryotic translation initiation factor 4A (eIF4A), a component of the translation initiation complex. Pdcd4 also suppresses the transactivation of activator protein-1 (AP-1)-responsive promoters by c-Jun. Pdcd4 contains two Akt phosphorylation sites, one at Ser67 and the other at Ser457. The phosphorylation of Pdcd4 by Akt causes nuclear translocation of Pdcd4 and a significant decrease in the ability of Pdcd4 to interfere with the transactivation of AP-1-responsive promoters by c-Jun."
"PDK1"	"PDK1-R-V_GBL9017448.txt"	"PDK1-R-V"	"Validated"	"Rabbit"	"CST"	"3062"	"Phosphoinositide-dependent protein kinase 1, involved in PI3K/AKT and PKC signaling"
"PDK1"	"PDK1_pS241-R-V_GBL9017295.txt"	"PDK1_pS241-R-V"	"Validated"	"Rabbit"	"CST"	"3061"	"Phosphoinositide-dependent protein kinase 1, involved in PI3K/AKT and PKC signaling"
"PEA15"	"PEA15-R-V_GBL9017394.txt"	"PEA15-R-V"	"Validated"	"Rabbit"	"CST"	"2780"	"Coordinate cell growth, death, and glucose utilization. Involved in MAPK  signaling"
"PEA15"	"PEA15_pS116-R-V_GBL9017449.txt"	"PEA15_pS116-R-V"	"Validated"	"Rabbit"	"Invitrogen"	"44-836G"	"Implicated in the regulation of multiple cellular processes including apoptosis, integrin activation, and insulin-sensitive glucose transport in insulin-responsive cells. Its activation mediated through binding to multiple proteins, including ERK1&2, RSK2, Akt, FADD, and Caspase-8."
"PIK3CA "	"PI3K-p110-alpha-R-C_GBL9017296.txt"	"PI3K-p110-alpha-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4255"	"One of the of the catalytic subunit of PI3K"
"PIK3R1 PIK3R2"	"PI3K-p85-R-V_GBL9017399.txt"	"PI3K-p85-R-V"	"Validated"	"Rabbit"	"Upstate (Millipore)"	"06-195"	"PI3K p85 regulatory subunit"
"PRKCA "	"PKC-alpha-M-V_GBL9017347.txt"	"PKC-alpha-M-V"	"Validated"	"Mouse"	"Upstate (Millipore)"	"05-154"	"PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions "
"PRKCA "	"PKC-alpha_pS657-R-V_GBL9017298.txt"	"PKC-alpha_pS657-R-V"	"Use with Caution"	"Rabbit"	"Upstate (Millipore)"	"06-822"	"PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions "
"PRKCD"	"PKC-delta_pS664-R-V_GBL9017393.txt"	"PKC-delta_pS664-R-V"	"Validated"	"Rabbit"	"Millipore"	"07-875"	"PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters."
"PRKCB"	"PKC-pan_BetaII_pS660-R-V_GBL9017510.txt"	"PKC-pan_BetaII_pS660-R-V"	"Validated"	"Rabbit"	"CST"	"9371"	"Activation of protein kinase C (PKC) is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction"
"PGR"	"PR-R-V_GBL9017299.txt"	"PR-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1483-1"	"Progesterone receptor, Transcription Factor"
"AKT1S1"	"PRAS40_pT246-R-V_GBL9017300.txt"	"PRAS40_pT246-R-V"	"Validated"	"Rabbit"	"Biosource"	"441100G"	"PRAS40 is a 14-3-3 binding protein that reacts with insulin. PRAS40 is phosphorylated by AKT"
"PRDX1"	"PRDX1-R-E_GBL9017511.txt"	"PRDX1-R-E"	"Under Evaluation"	"Rabbit"	"Sigma/Atlas"	"HPA007730"	"A member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. "
"PREX1"	"PREX1-R-E_GBL9017422.txt"	"PREX1-R-E"	"Under Evaluation"	"Rabbit"	"Abcam"	"ab102739"	"Downstream of Heterotrimric G proteins (Guanine nucleotide exchange factor)"
"PTEN"	"PTEN-R-V_GBL9017302.txt"	"PTEN-R-V"	"Validated"	"Rabbit"	"CST"	"9552"	"A lipid and protein phosphatase, a tumor suppressor, Major negative regulator of PI3K/AKT signaling"
"RAB11A RAB11B"	"Rab11-R-V_GBL9017303.txt"	"Rab11-R-V"	"Under Evaluation"	"Rabbit"	"CST"	"3539"	"Rab11 family posseses small Ras-like GTPase activity. Rab11 family includes Rab11a, Rab11b and Rab25 "
"RAB25"	"Rab25-R-V_GBL9017762.txt"	"Rab25-R-V"	"Validated"	"Rabbit"	"CST"	"4314"	"A member of Rab11 family posseses small Ras-like GTPase activity.  Increased Rab25 expression is associated with aggressive growth in ovarian and breast cancer, where Rab25 may inhibit apoptosis and promote cancer cell proliferation and invasion through regulation of vesicle transport and cellular motility."
"RAD50"	"Rad50-M-C_GBL9017348.txt"	"Rad50-M-C"	"Validated"	"Mouse"	"Millipore"	"05-525"	"Involved in DNA double-strand break repair"
"RAD51"	"Rad51-M-C_GBL9017349.txt"	"Rad51-M-C"	"Under Evaluation"	"Mouse"	"Chem Biotech"	"na 71"	"Involved in DNA double-strand break repair"
"RPTOR"	"Raptor-R-V_GBL9017512.txt"	"Raptor-R-V"	"Validated"	"Rabbit"	"CST"	"2280"	"The regulatory associated protein of mTOR (Raptor) was identified as an mTOR binding partner that mediates mTOR signaling to downstream targets. Recently raptor has been identified as a direct substrate of the AMP-activated protein kinase (AMPK). "
"RB1"	"Rb-M-V_GBL9017352.txt"	"Rb-M-V"	"**Used for QC**"	"Mouse"	"CST"	"9309"	"The retinoblastoma tumor suppressor protein Rb regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle. Rb has three functionally distinct binding domains and interacts with critical regulatory proteins including the E2F family of transcription factors, c-Abl tyrosine kinase, and proteins with a conserved LXCXE motif (2-4). Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo."
"RBM15"	"RBM15-R-V_GBL9017768.txt"	"RBM15-R-V"	"Validated"	"Rabbit"	"SDI / Novus"	"21390002"	"RBM15, have repressor function in several signaling pathways"
"RB1"	"Rb_pS807_S811-R-V_GBL9017307.txt"	"Rb_pS807_S811-R-V"	"Validated"	"Rabbit"	"CST"	"9308"	"The retinoblastoma tumor suppressor protein regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle"
"RICTOR"	"Rictor-R-C_GBL9017514.txt"	"Rictor-R-C"	"UsewithCaution"	"Rabbit"	"CST"	"2114"	"Rapamycin-insensitive companion of mTOR mediate rictor-mTOR signaling and phosphorylates Akt/PKB on Ser473 required for the full activation of AKT"
"RICTOR"	"Rictor_pT1135-R-V_GBL9017515.txt"	"Rictor_pT1135-R-V"	"Validated"	"Rabbit"	"CST"	"3806"	"Rapamycin-insensitive companion of mTOR mediate rictor-mTOR signaling and phosphorylates Akt/PKB on Ser473 required for the full activation of AKT"
"RPS6"	"S6-R-E_GBL9017390.txt"	"S6-R-E"	"Under Evaluation"	"Rabbit"	"CST"	"2217"	"Down stream of PI3K/AKT/mTOR/p70 S6 kinase, Involved in growth factors and mitogens induced protein translation"
"RPS6"	"S6_pS235_S236-R-V_GBL9017308.txt"	"S6_pS235_S236-R-V"	"Validated"	"Rabbit"	"CST"	"2211"	"Down stream of PI3K/AKT/mTOR/p70 S6 kinase, Involved in growth factors and mitogens induced protein translation"
"RPS6"	"S6_pS240_S244-R-V_GBL9017309.txt"	"S6_pS240_S244-R-V"	"Validated"	"Rabbit"	"CST"	"2215"	"Down stream of PI3K/AKT/mTOR/p70 S6 kinase, Involved in growth factors and mitogens induced protein translation"
"SCD"	"SCD-M-V_GBL9017774.txt"	"SCD-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-58420"	"Stearoyl-CoA desaturase (SCD) is a microsomal enzyme required for the synthesis of oleate and palmitoleate, which are the major monounsaturated fatty acids of membrane phospholipids, triglycerides and cholesterol esters."
"SETD2"	"SETD2-R-E_GBL9017395.txt"	"SETD2-R-E"	"**Used for QC**"	"Rabbit"	"Abcam"	"ab69836"	"SETD2 is a Histone methyltransferase that methylates 'Lys-36' of histone H3. H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. Probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. Binds DNA at promoters. May also act as a transcription activator that binds to promoters. Binds to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression."
"SRSF1"	"SF2-M-V_GBL9017775.txt"	"SF2-M-V"	"Validated"	"Mouse"	"Invitrogen"	"32-4500"	"The SF proteins are essential splicing factors and also regulate alternative splicing of many pre-mRNAs."
"SHC1"	"Shc_pY317-R-E_GBL9017310.txt"	"Shc_pY317-R-E"	"Validated"	"Rabbit"	"CST"	"2431"	"Serves as a scaffold protein in signaling for a variety of receptor tyrosine kinases"
"SLC1A5"	"SLC1A5-R-C_GBL9017783.txt"	"SLC1A5-R-C"	""	""	""	""	""
"DIABLO"	"Smac-M-V_GBL9017401.txt"	"Smac-M-V"	"**Used for QC**"	"Mouse"	"CST"	"2954"	"Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases. This interaction involves mainly the amino-terminal residues of Smac/Diablo with the BIR3 region of XIAP, supplemented with several other hydrophobic interactions between the helical structures of Smac/Diablo and other areas of BIR3."
"SMAD1"	"Smad1-R-V_GBL9017311.txt"	"Smad1-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1649-1"	"Mediates TGF beta signaling"
"SMAD3"	"Smad3-R-V_GBL9017312.txt"	"Smad3-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1735-1"	"Mediates TGF beta signaling"
"SMAD4"	"Smad4-M-V_GBL9017371.txt"	"Smad4-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-7966"	"Mediates TGF beta signaling"
"SNAI1"	"Snail-M-C_GBL9017372.txt"	"Snail-M-C"	"**Used for QC**"	"Mouse"	"CST"	"3895"	"Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells. Indeed, loss of E-cadherin expression is correlated with the invasive properties of some tumors and there is a considerable inverse correlation between Snail and E-cadherin mRNA levels in epithelial tumor cell lines. In addition, Snail blocks the cell cycle and confers resistance to cell death. Phosphorylation of Snail by GSK-3 and PAK1 regulates its stability, cellular localization and function."
"SRC"	"Src-M-V_GBL9017373.txt"	"Src-M-V"	"Validated"	"Mouse"	"Upstate (Millipore)"	"05-184"	"A member of Src family of protein tyrosine kinases"
"SRC"	"Src_pY416-R-C_GBL9017313.txt"	"Src_pY416-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2101"	"A member of Src family of protein tyrosine kinases"
"SRC"	"Src_pY527-R-V_GBL9017314.txt"	"Src_pY527-R-V"	"Validated"	"Rabbit"	"CST"	"2105"	"A member of Src family of protein tyrosine kinases"
"STAT3"	"STAT3_pY705-R-V_GBL9017315.txt"	"STAT3_pY705-R-V"	"Validated"	"Rabbit"	"CST"	"9131"	"Signal transducer and activator of transcription 3 functions both in signal transduction and activation of transcription"
"STAT5A"	"STAT5-alpha-R-V_GBL9017316.txt"	"STAT5-alpha-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1289-1"	"Signal transducer and activator of transcription 5 functions both in signal transduction and activation of transcription"
"STMN1"	"Stathmin-R-V_GBL9017317.txt"	"Stathmin-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1972-1"	"Ubiquitous cytosolic phosphoprotein"
"SYK"	"Syk-M-V_GBL9017374.txt"	"Syk-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-1240"	"One of several members of the protein kinase superfamily involved in PI3K and PLC signaling"
"WWTR1"	"TAZ-R-C_GBL9017391.txt"	"TAZ-R-C"	"Validated"	"Rabbit"	"CST"	"2149"	"Transcriptional co-activator"
"TFRC"	"TFRC-R-V_GBL9017769.txt"	"TFRC-R-V"	"Validated"	"Rabbit"	"SDI / Novus"	"22500002"	"Transferrin Receptor"
"TIGAR"	"TIGAR-R-V_GBL9017763.txt"	"TIGAR-R-V"	"Under Evaluation"	"Rabbit"	"Epitomics"	"S1711"	"Regulates p53 tumor suppresor pathway and glycolysis"
"TGM2"	"Transglutaminase-M-V_GBL9017405.txt"	"Transglutaminase-M-V"	"Validated"	"Mouse"	"Lab Vision"	"MS-224"	"Transglutaminases catalyze the posttranslational modification of proteins by transamidation of available glutamine residues. Reported to facilitate breast cancer metastasis."
"TSC1"	"TSC1-R-C_GBL9017517.txt"	"TSC1-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4906"	"The tumor suppressor genes TSC1 encode hamartin functions as a GTPase-activating protein for the Ras-related small G protein Rheb and thus inhibits targets of rapamycin including mTOR to regulate G1 phase of the cell cycle, steroid hormone regulation, Rho activation and anchoring neuronal intermediate filaments to the actin cytoskeleton. "
"TSC2"	"Tuberin-R-C_GBL9017319.txt"	"Tuberin-R-C"	"Validated"	"Rabbit"	"Epitomics"	"1613-1"	"Tuberous sclerosis complex-2 (TSC2 also known as Tuberin) is a tumor suppressor that forms a complex with TSC1 (Hamartin ) and this complex is known to control various cellular functions including cell cycle, endocytosis, adhesion, and transcription. Involved in AKT/mTOR signaling. "
"TSC2"	"Tuberin_pT1462-R-V_GBL9017760.txt"	"Tuberin_pT1462-R-V"	"Validated"	"Rabbit"	"CST"	"3617"	"Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Involved in AKT/mTOR signaling. "
"KDR"	"VEGFR2-R-C_GBL9017386.txt"	"VEGFR2-R-C"	"Validated"	"Rabbit"	"CST"	"2479"	"A major receptor for VEGF-induced signaling in endothelial cells"
"VHL"	"VHL-M-C_GBL9017776.txt"	"VHL-M-C"	"Use with Caution"	"Mouse"	"BD Pharmingen"	"556347"	"Transfection Factor"
"XBP1"	"XBP1-G-C_GBL9017406.txt"	"XBP1-G-C"	"Use with Caution"	"Goat"	"Santa Cruz"	"sc-32136"	"The X-box binding protein-1 plays a role in regulation of expression of osteoblast-specific genes."
"XRCC1"	"XRCC1-R-C_GBL9017412.txt"	"XRCC1-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2735"	"A DNA repair protein important in both single strand break repair and base excision repair following damage from ionizing radiation and alkylating agents"
"YAP1"	"YAP-R-V_GBL9017324.txt"	"YAP-R-V"	"Under Evaluation"	"Rabbit"	"Santa Cruz"	"sc-15407"	"Involved in Src, AKT and MAPK signaling"
"YAP1"	"YAP_pS127-R-C_GBL9017325.txt"	"YAP_pS127-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"4911"	"Involved in Src, AKT and MAPK signaling"
"YBX1"	"YB-1-R-V_GBL9017367.txt"	"YB-1-R-V"	"Validated"	"Rabbit"	"SDI"	"1725.00.02"	"Belongs to a family of evolutionarily conserved, multifunctional Y-box proteins that bind to DNA and RNA,  function as regulators of transcription, RNA metabolism, and protein synthesis"
"YBX1"	"YB-1_pS102-R-V_GBL9017327.txt"	"YB-1_pS102-R-V"	"Validated"	"Rabbit"	"CST"	"2900"	"Belongs to a family of evolutionarily conserved, multifunctional Y-box proteins that bind to DNA and RNA,  function as regulators of transcription, RNA metabolism, and protein synthesis"
"YWHAB"	"14-3-3_beta-R-V_GBL9025124.txt"	"14-3-3_beta-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"sc-628"	"14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints"
"YWHAE"	"14-3-3_epsilon-M-C_GBL9025015.txt"	"14-3-3_epsilon-M-C"	"Use with Caution"	"Mouse"	"Santa Cruz"	"sc-23957"	"14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints"
"YWHAZ"	"14-3-3_zeta-R-V_GBL9025125.txt"	"14-3-3_zeta-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"sc-1019"	"14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints"
"EIF4EBP1"	"4E-BP1-R-V_GBL9024810.txt"	"4E-BP1-R-V"	"Validated"	"Rabbit"	"CST"	"9452"	"Involves in protein translation. Regulated by PI3K/AKT/mTOR pathway"
"EIF4EBP1"	"4E-BP1_pS65-R-V_GBL9024811.txt"	"4E-BP1_pS65-R-V"	"Validated"	"Rabbit"	"CST"	"9456"	"Involves in protein translation. Regulated by PI3K/AKT/mTOR pathway"
"EIF4EBP1"	"4E-BP1_pT37_T46-R-V_GBL9024978.txt"	"4E-BP1_pT37_T46-R-V"	"Validated"	"Rabbit"	"CST"	"9459"	"Involves in protein translation. Regulated by PI3K/AKT/mTOR pathway"
"EIF4EBP1"	"4E-BP1_pT70-R-C_GBL9025061.txt"	"4E-BP1_pT70-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9455"	"Involved in protein translation, Regulated my PI3K/AKT/mTOR pathway"
"TP53BP1"	"53BP1-R-C_GBL9024812.txt"	"53BP1-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"4937"	"Identified as a p53 binding partner that could enhance the transcriptional activity of p53., Also involves in DNA repair signaling"
"ACACA"	"ACC1-R-C_GBL9024814.txt"	"ACC1-R-C"	"Under Evaluation"	"Rabbit"	"Epitomics"	"1768-1"	"Key enzyme in the biosynthesis and oxidation of fatty acids. Involved in energy homeostasis regulation"
"ACACA ACACB"	"ACC_pS79-R-V_GBL9024813.txt"	"ACC_pS79-R-V"	"Validated"	"Rabbit"	"CST"	"3661"	"Key enzyme in the biosynthesis and oxidation of fatty acids. Involved in energy homeostasis regulation"
"TUBA1B"	"Acetyl-a-Tubulin-Lys40-R-E_GBL9025103.txt"	"Acetyl-a-Tubulin-Lys40-R-E"	"Under Evaluation"	"Rabbit"	"CST"	"5335"	"The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Acetylation of _-tubulin at Lys40 is required for dynamic cell shape remodeling, cell motility, tubulin stability and terminal branching of cortical neurons"
"ACVRL1"	"ACVRL1-R-C_GBL9025126.txt"	"ACVRL1-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"2940-1"	"TNF beta superfamily"
"AKT1 AKT2 AKT3"	"Akt-R-V_GBL9024815.txt"	"Akt-R-V"	"Validated"	"Rabbit"	"CST"	"9272"	"PI3K/AKT/mTOR pathway"
"AKT1 AKT2 AKT3"	"Akt_pS473-R-V_GBL9024816.txt"	"Akt_pS473-R-V"	"Validated"	"Rabbit"	"CST"	"9271"	"PI3K/AKT/mTOR pathway"
"AKT1 AKT2 AKT3"	"Akt_pT308-R-V_GBL9024817.txt"	"Akt_pT308-R-V"	"Validated"	"Rabbit"	"CST"	"9275"	"PI3K/AKT/mTOR pathway"
"PRKAA1"	"AMPK_alpha-R-C_GBL9024818.txt"	"AMPK_alpha-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2532"	"Involved in energy homeostasis regulation"
"PRKAA1"	"AMPK_pT172-R-V_GBL9024819.txt"	"AMPK_pT172-R-V"	"Validated"	"Rabbit"	"CST"	"2535"	"Involved in energy homeostasis regulation"
"ANXA1"	"Annexin-1-M-E_GBL9025131.txt"	"Annexin-1-M-E"	"Under Evaluation"	"Mouse"	"BD Transduction"	"610066"	"Apoptosis"
"ANXA7"	"Annexin_VII-M-V_GBL9025112.txt"	"Annexin_VII-M-V"	"Validated"	"Mouse"	"BD Biosciences"	"610668"	"Apoptosis"
"AR"	"AR-R-V_GBL9024821.txt"	"AR-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1852-1"	"Androgen receptor (AR). Transcription Factor"
"ARAF"	"A-Raf_pS299-R-C_GBL9023107.txt"	"A-Raf_pS299-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4431"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"DIRAS3"	"ARHI-M-E_GBL9025132.txt"	"ARHI-M-E"	"Under Evaluation"	"Mouse"	"Dr. Robert C Bast Jr."	"Customer made"	"A member of the ras superfamily, Expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers."
"ARID1A"	"ARID1A-M-V_GBL9025030.txt"	"ARID1A-M-V"	"Validated"	"Mouse"	"Abgent"	"AT1188a"	"Involves in PI3K/PTEN signaling"
"ASNS"	"ASNS-R-C_GBL9024990.txt"	"ASNS-R-C"	"Validated"	"Rabbit"	"Sigma"	"HPA029318"	"The protein encoded by ASNS gene is involved in the synthesis of asparagine. "
"ATM"	"ATM-R-C_GBL9024991.txt"	"ATM-R-C"	"Under Evaluation"	"Rabbit"	"Abcam"	"ab32420"	"Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. "
"BAD"	"Bad_pS112-R-V_GBL9024822.txt"	"Bad_pS112-R-V"	"Validated"	"Rabbit"	"CST"	"9291"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein "
"BAK1"	"Bak-R-C_GBL9024823.txt"	"Bak-R-C"	"Under Evaluation"	"Rabbit"	"Epitomics"	"1542-1"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein "
"BAP1"	"Bap1-c-4-M-V_GBL9025120.txt"	"Bap1-c-4-M-V"	"Ender Evaluation"	"Rabbit"	"Alomine"	"APC-125"	"BAP1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization"
"BAX"	"Bax-R-V_GBL9024824.txt"	"Bax-R-V"	"Validated"	"Rabbit"	"CST"	"2772"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein "
"BCL2"	"Bcl-2-M-V_GBL9025018.txt"	"Bcl-2-M-V"	"Validated"	"Mouse"	"Dako"	"Dako M0887"	"Anti-apoptotic protein, Oncoprotein"
"BCL2L1"	"Bcl-xL-R-V_GBL9024826.txt"	"Bcl-xL-R-V"	"Validated"	"Rabbit"	"CST"	"2762"	"Bcl-2 interacting mediator of cell death, anti-apoptotic protein "
"BECN1"	"Beclin-G-V_GBL9025050.txt"	"Beclin-G-V"	"Use with Caution"	"Goat"	"Santa Cruz"	"sc-10086"	"BECN1 (Beclin 1) is a coiled-coil protein that has been implicated as an inhibitor of tumorigenesis. BECN1, which associates with Bcl-2, plays a significant role in autophagy."
"CTNNB1"	"beta-Catenin-R-V_GBL9024835.txt"	"beta-Catenin-R-V"	"Validated"	"Rabbit"	"CST"	"9562"	"Downstream effector in the Wnt signaling pathway"
"BID"	"Bid-R-C_GBL9024827.txt"	"Bid-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1008-1"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein belonging to the BH3-interaction protein"
"BCL2L11"	"Bim-R-V_GBL9024828.txt"	"Bim-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1036-1"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein belonging to the BH3-interaction protein"
"BRAF"	"B-Raf-M-C_GBL9025113.txt"	"B-Raf-M-C"	"Use with Caution"	"Mouse"	"Santa Cruz"	"sc-5284"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"BRCA2"	"BRCA2-R-C_GBL9023108.txt"	"BRCA2-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9012"	"The breast cancer susceptibility protein BRCA2 has roles in multiple processes related to DNA damage, repair, cell cycle progression, transcription, ubiquitination, and apoptosis"
"CASP7"	"Caspase-7_cleavedD198-R-C_GBL9024833.txt"	"Caspase-7_cleavedD198-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9491"	"A major contributor to the execution of apoptosis"
"CASP8"	"Caspase-8-M-C_GBL9025031.txt"	"Caspase-8-M-C"	"**Used for QC**"	"Mouse"	"CST"	"9746"	"Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10. Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7. Caspase-3 ultimately elicits the morphological hallmarks of apoptosis, including DNA fragmentation and cell shrinkage."
"CAV1"	"Caveolin-1-R-V_GBL9024836.txt"	"Caveolin-1-R-V"	"Validated"	"Rabbit"	"CST"	"3238"	"One of the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Interact with multiple signaling molecules such as G_ subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases, and eNOS"
"MS4A1"	"CD20-R-C_GBL9024993.txt"	"CD20-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1632"	"Human B lymphocyte surfacr marker"
"PECAM1"	"CD31-M-V_GBL9025073.txt"	"CD31-M-V"	"Validated"	"Mouse"	"Dako"	"M0823"	"Endothelia cell marker"
"ITGA2"	"CD49b-M-V_GBL9025032.txt"	"CD49b-M-V"	"Validated"	"Mouse"	"BD"	"611016"	"Integrin"
"CDK1"	"CDK1-R-V_GBL9024837.txt"	"CDK1-R-V"	"Validated"	"Rabbit"	"CST"	"9112"	"Involved in the regulation of the entry of eukaryotic cells into mitosis"
"CHEK1"	"Chk1-R-C_GBL9024838.txt"	"Chk1-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2345"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"CHEK1"	"Chk1_pS345-R-C_GBL9025079.txt"	"Chk1_pS345-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2348"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"CHEK2"	"Chk2-M-C_GBL9025074.txt"	"Chk2-M-C"	"Under Evaluation"	"Mouse"	"CST"	"3440"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"CHEK2"	"Chk2_pT68-R-C_GBL9024840.txt"	"Chk2_pT68-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2197"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"BIRC2 "	"cIAP-R-V_GBL9024841.txt"	"cIAP-R-V"	"Use with Caution"	"Rabbit"	"Millipore"	"07-759"	"Apoptosis suppressor"
"JUN"	"c-Jun_pS73-R-C_GBL9024872.txt"	"c-Jun_pS73-R-C"	"Validated"	"Rabbit"	"CST"	"9164"	"MAPK pathway, A component of the transcription factor activator protein-1 (AP-1), Regulates cell proliferation, differentiation, and apoptosis, as well as transformation, invasion and metastasis"
"KIT"	"c-Kit-R-V_GBL9024873.txt"	"c-Kit-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1522"	"Tyrosine Kinase Receptor"
"CLDN7"	"Claudin-7-R-V_GBL9024842.txt"	"Claudin-7-R-V"	"Validated"	"Rabbit"	"Novus"	"NB100-91714"	"Claudins  make up tight junction strands."
"MET"	"c-Met-M-C_GBL9025020.txt"	"c-Met-M-C"	"**Used for QC**"	"Mouse"	"CST"	"3127"	"Met, a high affinity tyrosine kinase receptor for hepatocyte growth factor (HGF, also known as scatter factor) is a disulfide-linked heterodimer made of 45 kDa ?- and 145 kDa ?-subunits. The ?-subunit and the amino-terminal region of the ?-subunit form the extracellular domain. The remainder of the ?-chain spans the plasma membrane and contains a cytoplasmic region with tyrosine kinase activity. Interaction of Met with HGF results in autophosphorylation at multiple tyrosines, which recruit several downstream signaling components, including Gab1, c-Cbl, and PI3 kinase. These fundamental events are important for all of the biological functions involving Met kinase activity. The addition of a phosphate at cytoplasmic Tyr1003 is essential for Met protein ubiquitination and degradation. Phosphorylation at Tyr1234/1235 in the Met kinase domain is critical for kinase activation. Phosphorylation at Tyr1349 in the Met cytoplasmic domain provides a direct binding site for Gab1. Research studies have shown that altered Met levels and/or tyrosine kinase activities are found in several types of tumors, including renal, colon, and breast. Thus, investigators have concluded that Met is an attractive potential cancer therapeutic and diagnostic target."
"MET"	"c-Met_pY1235-R-C_GBL9024877.txt"	"c-Met_pY1235-R-C"	"Validated"	"Rabbit"	"CST"	"3129"	"Tyrosine kinase receptor for hepatocyte growth factor"
"MYC"	"c-Myc-R-C_GBL9025060.txt"	"c-Myc-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9402"	"Members of the Myc/Max/Mad network function as transcriptional regulators invlolving in proliferation, differentiation and apoptosis"
"COL6A1"	"Collagen_VI-R-V_GBL9024843.txt"	"Collagen_VI-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"SC-20649"	"Collagens are fibrous, extracellular matrix proteins play a role in cell adhesion, important for maintaining normal tissue architecture and function."
"RAF1"	"C-Raf-R-V_GBL9024908.txt"	"C-Raf-R-V"	"Validated"	"Rabbit"	"Millipore"	"05-739"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"RAF1"	"C-Raf_pS338-R-C_GBL9024909.txt"	"C-Raf_pS338-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"9427"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"CCNB1"	"Cyclin_B1-R-V_GBL9024845.txt"	"Cyclin_B1-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1495-1"	"Cyclin B1 regulates mitosis. Cyclin B1 levels rise during S phase and G2, and peak at mitosis. "
"CCND1"	"Cyclin_D1-R-V_GBL9024846.txt"	"Cyclin_D1-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"SC-718"	"Cyclin D corresponds to a putative human oncogene. It regulates phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors"
"CCNE1"	"Cyclin_E1-M-V_GBL9024946.txt"	"Cyclin_E1-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"SC-247"	"Cyclin E has been found to be associated with the transcription factor E2F in a temporally regulated manner. The cyclin E/E2F complex is detected primarily during the G1 phase of the cell cycle and decreases as cells enter S phase. E2F is known to be a critical transcription factor for expression of several S phase specific proteins."
"CCNE2"	"Cyclin_E2-R-C_GBL9024994.txt"	"Cyclin_E2-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1142"	"Controls cell cycle at late G1 and early S phase"
"PARK7"	"DJ-1-R-C_GBL9024847.txt"	"DJ-1-R-C"	"Validated"	"Rabbit"	"Abcam"	"ab76008"	"May involved in regulation of PTEN expression"
"DVL3"	"Dvl3-R-V_GBL9024848.txt"	"Dvl3-R-V"	"Validated"	"Rabbit"	"CST"	"3218"	"Intermediates of Wnt signaling pathways"
"CDH1"	"E-Cadherin-R-V_GBL9024829.txt"	"E-Cadherin-R-V"	"Validated"	"Rabbit"	"CST"	"4065"	"A member of transmembrane glycoprotein superfamily, Mediate calcium-dependent cell-cell adhesion and normal tissue development. "
"EEF2"	"eEF2-R-V_GBL9024849.txt"	"eEF2-R-V"	"Use with Caution"	"Rabbit"	"CST"	"2332"	"Eukaryotic elongation factor 2 (eEF2) catalyzes the translocation of peptidyl-tRNA from the A site to the P site on the ribosome. Insulin induces rapid dephosphorylation of eEF2 through mTOR signaling."
"EEF2K"	"eEF2K-R-V_GBL9024850.txt"	"eEF2K-R-V"	"Validated"	"Rabbit"	"CST"	"3692"	"Eukaryotic elongation factor 2 kinase (eEF2k) phosphorylates and inactivates eEF2, resulting in the inhibition of peptide-chain elongation.p90RSK and p70 S6 kinase phosphorylate and inactivate eEF2k."
"EGFR"	"EGFR-R-E_GBL9025081.txt"	"EGFR-R-E"	"Validated"	"Rabbit"	"CST"	"2232"	"Epidermal growth factor receptor (EGFR), Tyrosine Kinase Receptor"
"EGFR"	"EGFR_pY1068-R-V_GBL9024852.txt"	"EGFR_pY1068-R-V"	"Use with Caution"	"Rabbit"	"CST"	"2234"	"Epidermal growth factor receptor (EGFR), Tyrosine Kinase Receptor"
"EGFR"	"EGFR_pY1173-R-C_GBL9025002.txt"	"EGFR_pY1173-R-C"	"Validated"	"Rabbit"	"Epitomics"	"1124"	"Epidermal growth factor receptor (EGFR), Tyrosine Kinase Receptor"
"EIF4E"	"eIF4E-R-V_GBL9024855.txt"	"eIF4E-R-V"	"Valid"	"Rabbit"	"CST"	"9742"	"Eukaryotic initiation factor 4E (eIF4E) binds to the mRNA cap structure to mediate the initiation of translation (1,2). eIF4E interacts with eIF4G, a scaffold protein that promotes assembly of eIF4E and eIF4A into the eIF4F complex (2). eIF4B is thought to assist the eIF4F complex in translation initiation. Upon activation by mitogenic and/or stress stimuli mediated by Erk and p38 MAPK, Mnk1 phosphorylates eIF4E at Ser209 in vivo (3,4). Two Erk and p38 MAPK phosphorylation sites in mouse Mnk1 (Thr197 and Thr202) are essential for Mnk1 kinase activity (3). The carboxy-terminal region of eIF4G also contains serum-stimulated phosphorylation sites, including Ser1108, Ser1148, and Ser1192 (5). Phosphorylation at these sites is blocked by the PI3 kinase inhibitor LY294002 and by the FRAP/mTOR inhibitor rapamycin."
"EIF4G1"	"eIF4G-R-C_GBL9023109.txt"	"eIF4G-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2498"	"Translation initiation factor"
"ESR1"	"ER-alpha-R-V_GBL9024856.txt"	"ER-alpha-R-V"	"Validated"	"Rabbit"	"Lab Vision"	"RM-9101-S"	"Estrogen receptor, Transcription Factor"
"ESR1"	"ER-alpha_pS118-R-V_GBL9024858.txt"	"ER-alpha_pS118-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1091-1"	"Estrogen receptor, Transcription Factor"
"ERCC1"	"ERCC1-M-C_GBL9025019.txt"	"ERCC1-M-C"	"**Used for QC**"	"Mouse"	"Lab Vision"	"MS-671-PO"	"Involved in DNA repaire"
"MAPK1"	"ERK2-R-C_GBL9024995.txt"	"ERK2-R-C"	"Under Evaluation"	"Rabbit"	"Santa Cruz"	"sc-154"	"Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42)."
"ETS1"	"ETS-1-R-V_GBL9025110.txt"	"ETS-1-R-V"	"Validated"	"Rabbit"	"BethYl"	"A303-501A"	"Ets-1 is a member of the ETS family of transcription factors"
"FASN"	"FASN-R-V_GBL9025090.txt"	"FASN-R-V"	"Validated"	"Rabbit"	"CST"	"3180"	"Fatty acid synthase (FASN) catalyzes the synthesis of long-chain fatty acids from acetyl-CoA and malonyl-CoA. Indicated as a poor prognosis in breast and prostate cancer. "
"FN1"	"Fibronectin-R-C_GBL9024857.txt"	"Fibronectin-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1574-1"	"Involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape"
"FOXM1"	"FoxM1-R-V_GBL9025091.txt"	"FoxM1-R-V"	"Validated"	"Rabbit"	"CST"	"5436"	"A forkhead box family transcription factor that regulates a number of genes throughout the cell cycle to help control DNA replication, mitosis and cell proliferation"
"FOXO3"	"FOXO3a-R-C_GBL9024860.txt"	"FOXO3a-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9467"	"Transcription Factor, involved in tyrosin kinase receptor and PI3K/AKT pathway"
"FOXO3"	"FOXO3a_pS318_S321-R-C_GBL9024861.txt"	"FOXO3a_pS318_S321-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9465"	"Transcription Factor, involved in tyrosin kinase receptor and PI3K/AKT pathway"
"G6PD"	"G6PD-M-V_GBL9025114.txt"	"G6PD-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-373887"	"Plays an important role in the pentose phosphate pathway"
"GAB2"	"GAB2-R-V_GBL9024996.txt"	"GAB2-R-V"	"Validated"	"Rabbit"	"CST"	"3239"	"Adaptor proteins recruited by a wide variety of receptor tyrosine kinases (RTKs) such as EGFR, HGFR, insulin receptor, cytokine receptor and B cell antigen receptors"
"GAPDH"	"GAPDH-M-C_GBL9025115.txt"	"GAPDH-M-C"	"Use with Caution"	"Mouse"	"Ambion"	"AM4300"	"Glyceraldehyde 3-phosphate dehydrogenase"
"GATA3"	"GATA3-M-V_GBL9024948.txt"	"GATA3-M-V"	"Validated"	"Mouse"	"BD Biosciences"	"558686"	"Transcription factor"
"GSK3A GSK3B"	"GSK3-alpha-beta-M-V_GBL9024949.txt"	"GSK3-alpha-beta-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"SC-7291"	"An enzyme that regulates glycogen synthesis in response to insulin, Also involved in Wnt signaling"
"GSK3A GSK3B"	"GSK3-alpha-beta_pS21_S9-R-V_GBL9024863.txt"	"GSK3-alpha-beta_pS21_S9-R-V"	"Validated"	"Rabbit"	"CST"	"9331"	"An enzyme that regulates glycogen synthesis in response to insulin, Also involved in Wnt signaling"
"GSK3A GSK3B"	"GSK3_pS9-R-V_GBL9024862.txt"	"GSK3_pS9-R-V"	"Validated"	"Rabbit"	"CST"	"9336"	"An enzyme that regulates glycogen synthesis in response to insulin, Also involved in Wnt signaling"
"ERBB2"	"HER2-M-V_GBL9024950.txt"	"HER2-M-V"	"Validated"	"Mouse"	"Lab Vision"	"MS-325-P1"	"The ErbB-2 proto-oncogene product"
"ERBB2"	"HER2_pY1248-R-V_GBL9024864.txt"	"HER2_pY1248-R-V"	"Use with Caution"	"Rabbit"	"Upstate (Millipore)"	"06-229"	"The ErbB-2 proto-oncogene product"
"ERBB3"	"HER3-R-V_GBL9024865.txt"	"HER3-R-V"	"Validated"	"Mouse"	"Lab Vision"	"MS-201-P1ABX"	"A member of the ErbB receptor protein tyrosine kinase family, but it lacks tyrosine kinase activity"
"ERBB3"	"HER3_pY1289-R-C_GBL9024866.txt"	"HER3_pY1289-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4791"	"A member of the ErbB receptor protein tyrosine kinase family, but it lacks tyrosine kinase activity"
"NRG1"	"Heregulin-R-V_GBL9025092.txt"	"Heregulin-R-V"	"Validated"	"Rabbit"	"CST"	"2573"	"A soluble growth factor synthesized as a transmembrane precursor molecule involved in HRG-ErbB3/ErbB4 signaling to regulate cell proliferation, differentiation, invasion, and survival of both normal and malignant tissues"
"HSPA1A"	"HSP70-R-C_GBL9025006.txt"	"HSP70-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4872"	"A molecular chaperone expressed constitutively under normal conditions to maintain protein homeostasis and are induced upon environmental stress"
"IGFBP2"	"IGFBP2-R-V_GBL9024868.txt"	"IGFBP2-R-V"	"Validated"	"Rabbit"	"CST"	"3922"	"Insulin-like growth factor-binding proteins (IGFBPs), Tyrosine kinase receptor"
"INPP4B"	"INPP4B-G-C_GBL9024968.txt"	"INPP4B-G-C"	"Under Evaluation"	"Goat"	"Santa Cruz"	"SC-12318"	"The inositol polyphosphate 4-phosphatases catalyze the hydrolysis of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate."
"IRS1"	"IRS1-R-V_GBL9024869.txt"	"IRS1-R-V"	"Validated"	"Rabbit"	"Upstate (Millipore)"	"06-248"	"Insulin receptor substrate (IRS) molecules are key mediators in insulin signaling and play a central role in maintaining basic cellular functions such as growth, survival, and metabolism. Involves in PI3K pathway."
"MAPK9"	"JNK2-R-C_GBL9024871.txt"	"JNK2-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4672"	"The stress-activated protein kinase, Belong to MAPK pathway (MKK4/7)"
"MAPK8"	"JNK_pT183_pY185-R-V_GBL9024870.txt"	"JNK_pT183_pY185-R-V"	"Validated"	"Rabbit"	"CST"	"4668"	"The stress-activated protein kinase, Belong to MAPK pathway (MKK4/7)"
"XRCC5"	"Ku80-R-C_GBL9025007.txt"	"Ku80-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2180"	"Functions as the DNA-binding regulatory component of DNA-dependent protein kinase (DNA-PK) involving in DNA repaire"
"LCK"	"Lck-R-V_GBL9025008.txt"	"Lck-R-V"	"Validated"	"Rabbit"	"CST"	"2752"	"A member of Src family of protein tyrosine kinases"
"STK11"	"LKB1-M-C_GBL9025033.txt"	"LKB1-M-C"	"Under Evaluation"	"Mouse"	"Abcam"	"ab15095"	"Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor."
"MAPK1 MAPK3"	"MAPK_pT202_Y204-R-V_GBL9024874.txt"	"MAPK_pT202_Y204-R-V"	"Validated"	"Rabbit"	"CST"	"4377"	"MAPK pathway (Mitogen-activated protein kinases), Regulates cell growth and differentiation"
"MAP2K1"	"MEK1-R-V_GBL9024875.txt"	"MEK1-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1235-1"	"MAPK pathway (Mitogen-activated protein kinases), Regulates cell growth and differentiation"
"MAP2K1"	"MEK1_pS217_S221-R-V_GBL9024876.txt"	"MEK1_pS217_S221-R-V"	"Validated"	"Rabbit"	"CST"	"9154"	"MAPK pathway (Mitogen-activated protein kinases), Regulates cell growth and differentiation"
"ERRFI1"	"MIG-6-M-V_GBL9025021.txt"	"MIG-6-M-V"	"Validated"	"Mouse"	"Sigma"	"WH0054206M1"	"ERRFI1 (MIG6) is a cytoplasmic protein whose expression is upregulated with cell growth "
"MRE11A"	"Mre11-R-C_GBL9024878.txt"	"Mre11-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4847"	"A central part of a multisubunit nuclease composed of Mre11, Rad50 and Nbs1 (MRN), Plays a critical role in sensing, processing and repairing DNA double strand breaks"
"MSH2"	"MSH2-M-C_GBL9025075.txt"	"MSH2-M-C"	"Validated"	"Mouse"	"CST"	"2850"	"MSH2 (MutS homologue 2) forms the hMutS-_ dimer with MSH6 and is an essential component of the mismatch DNA repair process. "
"MSH6"	"MSH6-R-C_GBL9024879.txt"	"MSH6-R-C"	"Use with Caution"	"Rabbit"	"Novus Biologicals"	"22030002"	"MSH6 is a mismatch-repair protein. It forms the hMutS-_ dimer with MSH2 and is an essential component of the mismatch DNA repair process. It plays a role in tumor suppression."
"MTOR"	"mTOR-R-V_GBL9024880.txt"	"mTOR-R-V"	"Validated"	"Rabbit"	"CST"	"2983"	"The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase, a major component of PI3K/AKT pathway"
"MTOR"	"mTOR_pS2448-R-C_GBL9024881.txt"	"mTOR_pS2448-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2971"	"The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase, a major component of PI3K/AKT pathway"
"MYH11"	"MYH11-R-V_GBL9025093.txt"	"MYH11-R-V"	"Validated"	"Rabbit"	"SDI / Novus"	"21370002"	"Myosin II forms bipolar filaments that interact with actin filaments to produce contraction."
"MYH9"	"Myosin-IIa_pS1943-R-V_GBL9025094.txt"	"Myosin-IIa_pS1943-R-V"	"Validated"	"Rabbit"	"CST"	"5026"	"Non muscle myosin is an actin-based motor protein essential to cell motility, cell division, migration, adhesion, and polarity"
"CDH2"	"N-Cadherin-R-V_GBL9025062.txt"	"N-Cadherin-R-V"	"Validated"	"Rabbit"	"CST"	"4061"	"A member of transmembrane glycoprotein superfamily, Mediate calcium-dependent cell-cell adhesion and normal tissue development. "
"NDRG1"	"NDRG1_pT346-R-V_GBL9025095.txt"	"NDRG1_pT346-R-V"	"Validated"	"Rabbit"	"CST"	"3217"	"A member of the NDRG family functions in growth, differentiation, and cell survival "
"NF2"	"NF2-R-C_GBL9024884.txt"	"NF2-R-C"	"Use with Caution"	"Rabbit"	"SDI"	"2271.00.02"	"Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals"
"NFKB1"	"NF-kB-p65_pS536-R-C_GBL9024883.txt"	"NF-kB-p65_pS536-R-C"	"Use with Caution"	"Rabbit"	"CST"	"3033"	"Transcription factors of the nuclear factor _ B (NF-_B)/Rel family play a pivotal role in inflammatory and immune responses "
"NOTCH1"	"Notch1-R-V_GBL9024885.txt"	"Notch1-R-V"	"Validated"	"Rabbit"	"CST"	"3268"	"A member of transmembrane receptor family that play important roles in development and the determination of cell fate "
"NRAS"	"N-Ras-M-V_GBL9025116.txt"	"N-Ras-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-31"	"The three Ras oncogenes, H-Ras, K-Ras and N-Ras, encode proteins with GTP/GDP binding and GTPase activity. Activates MAPK pathway."
"CDKN1A"	"p21-R-C_GBL9024887.txt"	"p21-R-C"	"Validated"	"Rabbit"	"Santa Cruz"	"SC-397"	"p21 is a potent, tight-binding inhibitor of Cdks and can inhibit the phosphorylation of Rb by cyclin A-Cdk 2, cyclin E-Cdk2, cyclin D1-Cdk4 and cyclin D2-Cdk4 complexes. Involves in p53 pathway and induces cell cycle arrest."
"CDKN1B"	"p27-R-V_GBL9024888.txt"	"p27-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1591-1"	"Regulates cell cycle arrest at G1 phase"
"CDKN1B"	"p27_pT157-R-C_GBL9024889.txt"	"p27_pT157-R-C"	"Use with Caution"	"Rabbit"	"R&D"	"AF1555"	"Regulates cell cycle arrest at G1 phase"
"CDKN1B"	"p27_pT198-R-V_GBL9024890.txt"	"p27_pT198-R-V"	"Validated"	"Rabbit"	"Abcam"	"ab64949"	"Involved in cell cycle arrest at G1 phase."
"MAPK14"	"p38_MAPK-R-C_GBL9024891.txt"	"p38_MAPK-R-C"	"Validated"	"Rabbit"	"CST"	"9212"	" A member of MAPKs. MKK3, MKK6, and SEK phosphorylate and activate p38 MAPK"
"MAPK14"	"p38_pT180_Y182-R-V_GBL9024892.txt"	"p38_pT180_Y182-R-V"	"Validated"	"Rabbit"	"CST"	"9211"	" A member of MAPKs. MKK3, MKK6, and SEK phosphorylate and activate p38 MAPK"
"TP53"	"p53-R-V_GBL9024893.txt"	"p53-R-V"	"Under Evaluation"	"Rabbit"	"CST"	"9282"	"Tumor suppressor and Transcription Factor, Regulates cell cycle arrest and apoptosis and DNA repair "
"SQSTM1"	"p62-LCK-ligand-M-E_GBL9025122.txt"	"p62-LCK-ligand-M-E"	"Under Evaluation"	"Mouse"	"BD Transduction Lab"	"610833"	"p62 lck ligand (zeta-interacting protein (ZIP)) is a cytoplasmic protein that binds to the SH2 domain of lck. It interacts with PKC_.."
"RPS6KB1"	"p70S6K-R-V_GBL9024894.txt"	"p70S6K-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1494-1"	"Mitogen-activated Ser/Thr protein kinase, Involved in PI3K, MAPK and PKC pathways"
"RPS6KB1"	"p70S6K_pT389-R-V_GBL9024895.txt"	"p70S6K_pT389-R-V"	"Validated"	"Rabbit"	"CST"	"9205"	"Mitogen-activated Ser/Thr protein kinase, Involved in PI3K, MAPK and PKC pathways"
"RPS6KA1"	"p90RSK-R-C_GBL9025096.txt"	"p90RSK-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9347"	"The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases involving in MAPK and PI3K signaling"
"RPS6KA1"	"p90RSK_pT359_S363-R-C_GBL9024896.txt"	"p90RSK_pT359_S363-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9344"	"The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases involving in MAPK and PI3K signaling"
"SERPINE1"	"PAI-1-M-C_GBL9025056.txt"	"PAI-1-M-C"	"Under Evaluation"	"Mouse"	"BD Biosciences"	"612024"	"PAI-1 is a glycoprotein involves in tissue plasminogen activator (tPA) and urokinase PA (uPA) signaling"
"PARP1"	"PARP_cleaved-M-C_GBL9025022.txt"	"PARP_cleaved-M-C"	"**Used for QC**"	"Mouse"	"CST"	"9546"	"PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress. This protein can be cleaved by many ICE-like caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. In human PARP, the cleavage occurs between Asp214 and Gly215, which separates the PARP amino-terminal DNA binding domain (24 kDa) from the carboxy-terminal catalytic domain (89 kDa). PARP helps cells to maintain their viability; cleavage of PARP facilitates cellular disassembly and serves as a marker of cells undergoing apoptosis."
"PXN"	"Paxillin-R-V_GBL9024897.txt"	"Paxillin-R-V"	"Use with Caution"	"Rabbit"	"Epitomics"	"1500-1"	"Involved in actin-membrane attachment, Regulates integrin signaling"
"CDH3"	"P-Cadherin-R-C_GBL9024982.txt"	"P-Cadherin-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2130"	"A member of transmembrane glycoprotein superfamily, Mediate calcium-dependent cell-cell adhesion and normal tissue development. "
"PCNA"	"PCNA-M-V_GBL9025076.txt"	"PCNA-M-V"	"Use with Caution"	"Mouse"	"Abcam"	"ab29"	"Involves in DNA repair"
"PDCD4"	"PDCD4-R-C_GBL9025097.txt"	"PDCD4-R-C"	"Use with Caution"	"Rabbit"	"Rockland"	"600-401-965"	"Pdcd4 directly inhibits the helicase activity of eukaryotic translation initiation factor 4A (eIF4A), a component of the translation initiation complex. Pdcd4 also suppresses the transactivation of activator protein-1 (AP-1)-responsive promoters by c-Jun. Pdcd4 contains two Akt phosphorylation sites, one at Ser67 and the other at Ser457. The phosphorylation of Pdcd4 by Akt causes nuclear translocation of Pdcd4 and a significant decrease in the ability of Pdcd4 to interfere with the transactivation of AP-1-responsive promoters by c-Jun."
"PDK1"	"PDK1-R-V_GBL9025098.txt"	"PDK1-R-V"	"Validated"	"Rabbit"	"CST"	"3062"	"Phosphoinositide-dependent protein kinase 1, involved in PI3K/AKT and PKC signaling"
"PDK1"	"PDK1_pS241-R-V_GBL9024898.txt"	"PDK1_pS241-R-V"	"Validated"	"Rabbit"	"CST"	"3061"	"Phosphoinositide-dependent protein kinase 1, involved in PI3K/AKT and PKC signaling"
"PEA15"	"PEA15-R-V_GBL9024985.txt"	"PEA15-R-V"	"Validated"	"Rabbit"	"CST"	"2780"	"Coordinate cell growth, death, and glucose utilization. Involved in MAPK  signaling"
"PEA15"	"PEA15_pS116-R-V_GBL9025099.txt"	"PEA15_pS116-R-V"	"Validated"	"Rabbit"	"Invitrogen"	"44-836G"	"Implicated in the regulation of multiple cellular processes including apoptosis, integrin activation, and insulin-sensitive glucose transport in insulin-responsive cells. Its activation mediated through binding to multiple proteins, including ERK1&2, RSK2, Akt, FADD, and Caspase-8."
"PIK3CA "	"PI3K-p110-alpha-R-C_GBL9024899.txt"	"PI3K-p110-alpha-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4255"	"One of the of the catalytic subunit of PI3K"
"PIK3R1 PIK3R2"	"PI3K-p85-R-V_GBL9024900.txt"	"PI3K-p85-R-V"	"Validated"	"Rabbit"	"Upstate (Millipore)"	"06-195"	"PI3K p85 regulatory subunit"
"PRKCA "	"PKC-alpha-M-V_GBL9025023.txt"	"PKC-alpha-M-V"	"Validated"	"Mouse"	"Upstate (Millipore)"	"05-154"	"PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions "
"PRKCA "	"PKC-alpha_pS657-R-V_GBL9024901.txt"	"PKC-alpha_pS657-R-V"	"Use with Caution"	"Rabbit"	"Upstate (Millipore)"	"06-822"	"PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions "
"PRKCD"	"PKC-delta_pS664-R-V_GBL9025077.txt"	"PKC-delta_pS664-R-V"	"Validated"	"Rabbit"	"Millipore"	"07-875"	"PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters."
"PRKCB"	"PKC-pan_BetaII_pS660-R-V_GBL9025100.txt"	"PKC-pan_BetaII_pS660-R-V"	"Validated"	"Rabbit"	"CST"	"9371"	"Activation of protein kinase C (PKC) is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction"
"PGR"	"PR-R-V_GBL9024902.txt"	"PR-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1483-1"	"Progesterone receptor, Transcription Factor"
"AKT1S1"	"PRAS40_pT246-R-V_GBL9024903.txt"	"PRAS40_pT246-R-V"	"Validated"	"Rabbit"	"Biosource"	"441100G"	"PRAS40 is a 14-3-3 binding protein that reacts with insulin. PRAS40 is phosphorylated by AKT"
"PRDX1"	"PRDX1-R-E_GBL9025101.txt"	"PRDX1-R-E"	"Under Evaluation"	"Rabbit"	"Sigma/Atlas"	"HPA007730"	"A member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. "
"PREX1"	"PREX1-R-E_GBL9025127.txt"	"PREX1-R-E"	"Under Evaluation"	"Rabbit"	"Abcam"	"ab102739"	"Downstream of Heterotrimric G proteins (Guanine nucleotide exchange factor)"
"PTEN"	"PTEN-R-V_GBL9024905.txt"	"PTEN-R-V"	"Validated"	"Rabbit"	"CST"	"9552"	"A lipid and protein phosphatase, a tumor suppressor, Major negative regulator of PI3K/AKT signaling"
"RAB11A RAB11B"	"Rab11-R-V_GBL9025013.txt"	"Rab11-R-V"	"Under Evaluation"	"Rabbit"	"CST"	"3539"	"Rab11 family posseses small Ras-like GTPase activity. Rab11 family includes Rab11a, Rab11b and Rab25 "
"RAB25"	"Rab25-R-V_GBL9025111.txt"	"Rab25-R-V"	"Validated"	"Rabbit"	"CST"	"4314"	"A member of Rab11 family posseses small Ras-like GTPase activity.  Increased Rab25 expression is associated with aggressive growth in ovarian and breast cancer, where Rab25 may inhibit apoptosis and promote cancer cell proliferation and invasion through regulation of vesicle transport and cellular motility."
"RAD50"	"Rad50-M-C_GBL9024957.txt"	"Rad50-M-C"	"Validated"	"Mouse"	"Millipore"	"05-525"	"Involved in DNA double-strand break repair"
"RAD51"	"Rad51-M-C_GBL9025024.txt"	"Rad51-M-C"	"Under Evaluation"	"Mouse"	"Chem Biotech"	"na 71"	"Involved in DNA double-strand break repair"
"RPTOR"	"Raptor-R-V_GBL9025102.txt"	"Raptor-R-V"	"Validated"	"Rabbit"	"CST"	"2280"	"The regulatory associated protein of mTOR (Raptor) was identified as an mTOR binding partner that mediates mTOR signaling to downstream targets. Recently raptor has been identified as a direct substrate of the AMP-activated protein kinase (AMPK). "
"RB1"	"Rb-M-V_GBL9025026.txt"	"Rb-M-V"	"**Used for QC**"	"Mouse"	"CST"	"9309"	"The retinoblastoma tumor suppressor protein Rb regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle. Rb has three functionally distinct binding domains and interacts with critical regulatory proteins including the E2F family of transcription factors, c-Abl tyrosine kinase, and proteins with a conserved LXCXE motif (2-4). Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo."
"RBM15"	"RBM15-R-V_GBL9025104.txt"	"RBM15-R-V"	"Validated"	"Rabbit"	"SDI / Novus"	"21390002"	"RBM15, have repressor function in several signaling pathways"
"RB1"	"Rb_pS807_S811-R-V_GBL9024910.txt"	"Rb_pS807_S811-R-V"	"Validated"	"Rabbit"	"CST"	"9308"	"The retinoblastoma tumor suppressor protein regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle"
"RICTOR"	"Rictor-R-C_GBL9025105.txt"	"Rictor-R-C"	"UsewithCaution"	"Rabbit"	"CST"	"2114"	"Rapamycin-insensitive companion of mTOR mediate rictor-mTOR signaling and phosphorylates Akt/PKB on Ser473 required for the full activation of AKT"
"RICTOR"	"Rictor_pT1135-R-V_GBL9025106.txt"	"Rictor_pT1135-R-V"	"Validated"	"Rabbit"	"CST"	"3806"	"Rapamycin-insensitive companion of mTOR mediate rictor-mTOR signaling and phosphorylates Akt/PKB on Ser473 required for the full activation of AKT"
"RPS6"	"S6-R-C_GBL9025009.txt"	"S6-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2217"	"Down stream of PI3K/AKT/mTOR/p70 S6 kinase, Involved in growth factors and mitogens induced protein translation"
"RPS6"	"S6_pS235_S236-R-V_GBL9024911.txt"	"S6_pS235_S236-R-V"	"Validated"	"Rabbit"	"CST"	"2211"	"Down stream of PI3K/AKT/mTOR/p70 S6 kinase, Involved in growth factors and mitogens induced protein translation"
"RPS6"	"S6_pS240_S244-R-V_GBL9024912.txt"	"S6_pS240_S244-R-V"	"Validated"	"Rabbit"	"CST"	"2215"	"Down stream of PI3K/AKT/mTOR/p70 S6 kinase, Involved in growth factors and mitogens induced protein translation"
"SCD"	"SCD-M-V_GBL9025117.txt"	"SCD-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-58420"	"Stearoyl-CoA desaturase (SCD) is a microsomal enzyme required for the synthesis of oleate and palmitoleate, which are the major monounsaturated fatty acids of membrane phospholipids, triglycerides and cholesterol esters."
"SETD2"	"SETD2-R-C_GBL9024987.txt"	"SETD2-R-C"	"**Used for QC**"	"Rabbit"	"Abcam"	"ab69836"	"SETD2 is a Histone methyltransferase that methylates 'Lys-36' of histone H3. H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. Probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. Binds DNA at promoters. May also act as a transcription activator that binds to promoters. Binds to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression."
"SRSF1"	"SF2-M-V_GBL9025118.txt"	"SF2-M-V"	"Validated"	"Mouse"	"Invitrogen"	"32-4500"	"The SF proteins are essential splicing factors and also regulate alternative splicing of many pre-mRNAs."
"SHC1"	"Shc_pY317-R-C_GBL9025054.txt"	"Shc_pY317-R-C"	"Validated"	"Rabbit"	"CST"	"2431"	"Serves as a scaffold protein in signaling for a variety of receptor tyrosine kinases"
"DIABLO"	"Smac-M-V_GBL9024961.txt"	"Smac-M-V"	"**Used for QC**"	"Mouse"	"CST"	"2954"	"Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases. This interaction involves mainly the amino-terminal residues of Smac/Diablo with the BIR3 region of XIAP, supplemented with several other hydrophobic interactions between the helical structures of Smac/Diablo and other areas of BIR3."
"SMAD1"	"Smad1-R-V_GBL9024913.txt"	"Smad1-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1649-1"	"Mediates TGF beta signaling"
"SMAD3"	"Smad3-R-V_GBL9024914.txt"	"Smad3-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1735-1"	"Mediates TGF beta signaling"
"SMAD4"	"Smad4-M-V_GBL9025078.txt"	"Smad4-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-7966"	"Mediates TGF beta signaling"
"SNAI1"	"Snail-M-C_GBL9024963.txt"	"Snail-M-C"	"**Used for QC**"	"Mouse"	"CST"	"3895"	"Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells. Indeed, loss of E-cadherin expression is correlated with the invasive properties of some tumors and there is a considerable inverse correlation between Snail and E-cadherin mRNA levels in epithelial tumor cell lines. In addition, Snail blocks the cell cycle and confers resistance to cell death. Phosphorylation of Snail by GSK-3 and PAK1 regulates its stability, cellular localization and function."
"SRC"	"Src-M-V_GBL9025027.txt"	"Src-M-V"	"Validated"	"Mouse"	"Upstate (Millipore)"	"05-184"	"A member of Src family of protein tyrosine kinases"
"SRC"	"Src_pY416-R-C_GBL9024915.txt"	"Src_pY416-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2101"	"A member of Src family of protein tyrosine kinases"
"SRC"	"Src_pY527-R-V_GBL9024916.txt"	"Src_pY527-R-V"	"Validated"	"Rabbit"	"CST"	"2105"	"A member of Src family of protein tyrosine kinases"
"STAT3"	"STAT3_pY705-R-V_GBL9024917.txt"	"STAT3_pY705-R-V"	"Validated"	"Rabbit"	"CST"	"9131"	"Signal transducer and activator of transcription 3 functions both in signal transduction and activation of transcription"
"STAT5A"	"STAT5-alpha-R-V_GBL9024918.txt"	"STAT5-alpha-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1289-1"	"Signal transducer and activator of transcription 5 functions both in signal transduction and activation of transcription"
"STMN1"	"Stathmin-R-V_GBL9024919.txt"	"Stathmin-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1972-1"	"Ubiquitous cytosolic phosphoprotein"
"SYK"	"Syk-M-V_GBL9025058.txt"	"Syk-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-1240"	"One of several members of the protein kinase superfamily involved in PI3K and PLC signaling"
"WWTR1"	"TAZ-R-C_GBL9025055.txt"	"TAZ-R-C"	"Validated"	"Rabbit"	"CST"	"2149"	"Transcriptional co-activator"
"TFRC"	"TFRC-R-V_GBL9025107.txt"	"TFRC-R-V"	"Validated"	"Rabbit"	"SDI / Novus"	"22500002"	"Transferrin Receptor"
"TIGAR"	"TIGAR-R-V_GBL9024922.txt"	"TIGAR-R-V"	"Under Evaluation"	"Rabbit"	"Epitomics"	"S1711"	"Regulates p53 tumor suppresor pathway and glycolysis"
"TGM2"	"Transglutaminase-M-V_GBL9024977.txt"	"Transglutaminase-M-V"	"Validated"	"Mouse"	"Lab Vision"	"MS-224"	"Transglutaminases catalyze the posttranslational modification of proteins by transamidation of available glutamine residues. Reported to facilitate breast cancer metastasis."
"TSC1"	"TSC1-R-C_GBL9025108.txt"	"TSC1-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4906"	"The tumor suppressor genes TSC1 encode hamartin functions as a GTPase-activating protein for the Ras-related small G protein Rheb and thus inhibits targets of rapamycin including mTOR to regulate G1 phase of the cell cycle, steroid hormone regulation, Rho activation and anchoring neuronal intermediate filaments to the actin cytoskeleton. "
"TSC2"	"Tuberin-R-C_GBL9024923.txt"	"Tuberin-R-C"	"Validated"	"Rabbit"	"Epitomics"	"1613-1"	"Tuberous sclerosis complex-2 (TSC2 also known as Tuberin) is a tumor suppressor that forms a complex with TSC1 (Hamartin ) and this complex is known to control various cellular functions including cell cycle, endocytosis, adhesion, and transcription. Involved in AKT/mTOR signaling. "
"TSC2"	"Tuberin_pT1462-R-V_GBL9025109.txt"	"Tuberin_pT1462-R-V"	"Validated"	"Rabbit"	"CST"	"3617"	"Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Involved in AKT/mTOR signaling. "
"KDR"	"VEGFR2-R-V_GBL9024925.txt"	"VEGFR2-R-V"	"Validated"	"Rabbit"	"CST"	"2479"	"A major receptor for VEGF-induced signaling in endothelial cells"
"VHL"	"VHL-M-C_GBL9025119.txt"	"VHL-M-C"	"Use with Caution"	"Mouse"	"BD Pharmingen"	"556347"	"Transfection Factor"
"XBP1"	"XBP1-G-C_GBL9025048.txt"	"XBP1-G-C"	"Use with Caution"	"Goat"	"Santa Cruz"	"sc-32136"	"The X-box binding protein-1 plays a role in regulation of expression of osteoblast-specific genes."
"XRCC1"	"XRCC1-R-C_GBL9024927.txt"	"XRCC1-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2735"	"A DNA repair protein important in both single strand break repair and base excision repair following damage from ionizing radiation and alkylating agents"
"YAP1"	"YAP-R-V_GBL9024928.txt"	"YAP-R-V"	"Under Evaluation"	"Rabbit"	"Santa Cruz"	"sc-15407"	"Involved in Src, AKT and MAPK signaling"
"YAP1"	"YAP_pS127-R-C_GBL9024929.txt"	"YAP_pS127-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"4911"	"Involved in Src, AKT and MAPK signaling"
"YBX1"	"YB-1-R-V_GBL9024997.txt"	"YB-1-R-V"	"Validated"	"Rabbit"	"SDI"	"1725.00.02"	"Belongs to a family of evolutionarily conserved, multifunctional Y-box proteins that bind to DNA and RNA,  function as regulators of transcription, RNA metabolism, and protein synthesis"
"YBX1"	"YB-1_pS102-R-V_GBL9024971.txt"	"YB-1_pS102-R-V"	"Validated"	"Rabbit"	"CST"	"2900"	"Belongs to a family of evolutionarily conserved, multifunctional Y-box proteins that bind to DNA and RNA,  function as regulators of transcription, RNA metabolism, and protein synthesis"
"YWHAB"	"14-3-3_beta-R-V_GBL1114584.txt"	"14-3-3_beta-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"sc-628"	"14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints"
"YWHAE"	"14-3-3_epsilon-M-C_GBL1114668.txt"	"14-3-3_epsilon-M-C"	"Use with Caution"	"Mouse"	"Santa Cruz"	"sc-23957"	"14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints"
"YWHAZ"	"14-3-3_zeta-R-V_GBL1114585.txt"	"14-3-3_zeta-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"sc-1019"	"14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints"
"EIF4EBP1"	"4E-BP1-R-V_GBL1114391.txt"	"4E-BP1-R-V"	"Validated"	"Rabbit"	"CST"	"9452"	"Involves in protein translation. Regulated by PI3K/AKT/mTOR pathway"
"EIF4EBP1"	"4E-BP1_pS65-R-V_GBL1114392.txt"	"4E-BP1_pS65-R-V"	"Validated"	"Rabbit"	"CST"	"9456"	"Involves in protein translation. Regulated by PI3K/AKT/mTOR pathway"
"EIF4EBP1"	"4E-BP1_pT37_T46-R-V_GBL1114393.txt"	"4E-BP1_pT37_T46-R-V"	"Validated"	"Rabbit"	"CST"	"9459"	"Involves in protein translation. Regulated by PI3K/AKT/mTOR pathway"
"EIF4EBP1"	"4E-BP1_pT70-R-V_GBL1114394.txt"	"4E-BP1_pT70-R-V"	"Use with Caution"	"Rabbit"	"CST"	"9455"	"Involved in protein translation, Regulated my PI3K/AKT/mTOR pathway"
"TP53BP1"	"53BP1-R-E_GBL1114598.txt"	"53BP1-R-E"	"Under Evaluation"	"Rabbit"	"CST"	"4937"	"Identified as a p53 binding partner that could enhance the transcriptional activity of p53., Also involves in DNA repair signaling"
"ACACA"	"ACC1-R-E_GBL1114396.txt"	"ACC1-R-E"	"Under Evaluation"	"Rabbit"	"Epitomics"	"1768-1"	"Key enzyme in the biosynthesis and oxidation of fatty acids. Involved in energy homeostasis regulation"
"ACACA ACACB"	"ACC_pS79-R-V_GBL1114395.txt"	"ACC_pS79-R-V"	"Validated"	"Rabbit"	"CST"	"3661"	"Key enzyme in the biosynthesis and oxidation of fatty acids. Involved in energy homeostasis regulation"
"TUBA1B"	"Acetyl-a-Tubulin-Lys40-R-C_GBL1114634.txt"	"Acetyl-a-Tubulin-Lys40-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"5335"	"The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Acetylation of _-tubulin at Lys40 is required for dynamic cell shape remodeling, cell motility, tubulin stability and terminal branching of cortical neurons"
"ACVRL1"	"ACVRL1-R-C_GBL1114613.txt"	"ACVRL1-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"2940-1"	"TNF beta superfamily"
"ADAR"	"ADAR1-M-V_GBL1114683.txt"	"ADAR1-M-V"	"Validated"	"Mouse"	"Abcam"	"ab88574"	"Converts multiple adenosines to inosines and creates I/U mismatched base pairs in double-helical RNA substrates without apparent sequence specificity. It plays a role in RNA editing."
"AKT1 AKT2 AKT3"	"Akt-R-V_GBL1114612.txt"	"Akt-R-V"	"Validated"	"Rabbit"	"CST"	"9272"	"PI3K/AKT/mTOR pathway"
"AKT1 AKT2 AKT3"	"Akt_pS473-R-V_GBL1114515.txt"	"Akt_pS473-R-V"	"Validated"	"Rabbit"	"CST"	"9271"	"PI3K/AKT/mTOR pathway"
"AKT1 AKT2 AKT3"	"Akt_pT308-R-V_GBL1114631.txt"	"Akt_pT308-R-V"	"Validated"	"Rabbit"	"CST"	"9275"	"PI3K/AKT/mTOR pathway"
"CTNNA1"	"alpha-Catenin-M-V_GBL1114670.txt"	"alpha-Catenin-M-V"	"Validated"	"Mouse"	"Calbiochem"	"CA1030"	"Discontinued"
"PRKAA1"	"AMPK_alpha-R-C_GBL1114397.txt"	"AMPK_alpha-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2532"	"Involved in energy homeostasis regulation"
"PRKAA1"	"AMPK_pT172-R-V_GBL1114465.txt"	"AMPK_pT172-R-V"	"Validated"	"Rabbit"	"CST"	"2535"	"Involved in energy homeostasis regulation"
"ANXA1"	"Annexin-1-M-E_GBL1114686.txt"	"Annexin-1-M-E"	"Under Evaluation"	"Mouse"	"BD Transduction"	"610066"	"Apoptosis"
"ANXA7"	"Annexin_VII-M-V_GBL1114680.txt"	"Annexin_VII-M-V"	"Validated"	"Mouse"	"BD Biosciences"	"610668"	"Apoptosis"
"AR"	"AR-R-V_GBL1114568.txt"	"AR-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1852-1"	"Androgen receptor (AR). Transcription Factor"
"ARAF"	"A-Raf_pS299-R-C_GBL1114522.txt"	"A-Raf_pS299-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4431"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"DIRAS3"	"ARHI-M-E_GBL1114687.txt"	"ARHI-M-E"	"Under Evaluation"	"Mouse"	"Dr. Robert C Bast Jr."	"Customer made"	"A member of the ras superfamily, Expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers."
"ASNS"	"ASNS-R-V_GBL1114640.txt"	"ASNS-R-V"	"Validated"	"Rabbit"	"Sigma"	"HPA029318"	"The protein encoded by ASNS gene is involved in the synthesis of asparagine. "
"ATM"	"ATM-R-E_GBL1114466.txt"	"ATM-R-E"	"Under Evaluation"	"Rabbit"	"Abcam"	"ab32420"	"Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. "
"BAD"	"Bad_pS112-R-V_GBL1114467.txt"	"Bad_pS112-R-V"	"Validated"	"Rabbit"	"CST"	"9291"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein "
"BAK1"	"Bak-R-C_GBL1114468.txt"	"Bak-R-C"	"Under Evaluation"	"Rabbit"	"Epitomics"	"1542-1"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein "
"BAP1"	"Bap1-c-4-M-V_GBL1114685.txt"	"Bap1-c-4-M-V"	"Ender Evaluation"	"Rabbit"	"Alomine"	"APC-125"	"BAP1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization"
"BAX"	"Bax-R-V_GBL1114469.txt"	"Bax-R-V"	"Validated"	"Rabbit"	"CST"	"2772"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein "
"BCL2"	"Bcl-2-M-V_GBL1114646.txt"	"Bcl-2-M-V"	"Validated"	"Mouse"	"Dako"	"Dako M0887"	"Anti-apoptotic protein, Oncoprotein"
"BCL2L1"	"Bcl-xL-R-V_GBL1114471.txt"	"Bcl-xL-R-V"	"Validated"	"Rabbit"	"CST"	"2762"	"Bcl-2 interacting mediator of cell death, anti-apoptotic protein "
"BECN1"	"Beclin-G-C_GBL1114641.txt"	"Beclin-G-C"	"Use with Caution"	"Goat"	"Santa Cruz"	"sc-10086"	"BECN1 (Beclin 1) is a coiled-coil protein that has been implicated as an inhibitor of tumorigenesis. BECN1, which associates with Bcl-2, plays a significant role in autophagy."
"CTNNB1"	"beta-Catenin-R-V_GBL1114470.txt"	"beta-Catenin-R-V"	"Validated"	"Rabbit"	"CST"	"9562"	"Downstream effector in the Wnt signaling pathway"
"BID"	"Bid-R-C_GBL1114472.txt"	"Bid-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1008-1"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein belonging to the BH3-interaction protein"
"BCL2L11"	"Bim-R-V_GBL1114473.txt"	"Bim-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1036-1"	"Bcl-2 interacting mediator of cell death, pro-apoptotic protein belonging to the BH3-interaction protein"
"BRAF"	"B-Raf-M-C_GBL1114647.txt"	"B-Raf-M-C"	"Use with Caution"	"Mouse"	"Santa Cruz"	"sc-5284"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"BRCA2"	"BRCA2-R-C_GBL1114570.txt"	"BRCA2-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9012"	"The breast cancer susceptibility protein BRCA2 has roles in multiple processes related to DNA damage, repair, cell cycle progression, transcription, ubiquitination, and apoptosis"
"CASP7"	"Caspase-7_cleavedD198-R-C_GBL1114474.txt"	"Caspase-7_cleavedD198-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9491"	"A major contributor to the execution of apoptosis"
"CASP8"	"Caspase-8-M-QC_GBL1114672.txt"	"Caspase-8-M-QC"	"**Used for QC**"	"Mouse"	"CST"	"9746"	"Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10. Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7. Caspase-3 ultimately elicits the morphological hallmarks of apoptosis, including DNA fragmentation and cell shrinkage."
"CAV1"	"Caveolin-1-R-V_GBL1114505.txt"	"Caveolin-1-R-V"	"Validated"	"Rabbit"	"CST"	"3238"	"One of the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Interact with multiple signaling molecules such as G_ subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases, and eNOS"
"MS4A1"	"CD20-R-C_GBL1114506.txt"	"CD20-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1632"	"Human B lymphocyte surfacr marker"
"PECAM1"	"CD31-M-V_GBL1114648.txt"	"CD31-M-V"	"Validated"	"Mouse"	"Dako"	"M0823"	"Endothelia cell marker"
"ITGA2"	"CD49b-M-V_GBL1114671.txt"	"CD49b-M-V"	"Validated"	"Mouse"	"BD"	"611016"	"Integrin"
"CDK1"	"CDK1-R-V_GBL1114599.txt"	"CDK1-R-V"	"Validated"	"Rabbit"	"CST"	"9112"	"Involved in the regulation of the entry of eukaryotic cells into mitosis"
"CHEK1"	"Chk1-M-C_GBL1114684.txt"	"Chk1-M-C"	"Under Evaluation"	"Rabbit"	"CST"	"2345"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"CHEK1"	"Chk1_pS345-R-C_GBL1114590.txt"	"Chk1_pS345-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2348"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"CHEK2"	"Chk2-M-E_GBL1114649.txt"	"Chk2-M-E"	"Under Evaluation"	"Mouse"	"CST"	"3440"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"CHEK2"	"Chk2_pT68-R-C_GBL1114507.txt"	"Chk2_pT68-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2197"	"Kinase acts downstream of ATM/ATR involving in DNA damage checkpoint control, embryonic development, and tumor suppression"
"BIRC2 "	"cIAP-R-V_GBL1114594.txt"	"cIAP-R-V"	"Use with Caution"	"Rabbit"	"Millipore"	"07-759"	"Apoptosis suppressor"
"JUN"	"c-Jun_pS73-R-V_GBL1114398.txt"	"c-Jun_pS73-R-V"	"Validated"	"Rabbit"	"CST"	"9164"	"MAPK pathway, A component of the transcription factor activator protein-1 (AP-1), Regulates cell proliferation, differentiation, and apoptosis, as well as transformation, invasion and metastasis"
"KIT"	"c-Kit-R-V_GBL1114645.txt"	"c-Kit-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1522"	"Tyrosine Kinase Receptor"
"CLDN7"	"Claudin-7-R-V_GBL1114582.txt"	"Claudin-7-R-V"	"Validated"	"Rabbit"	"Novus"	"NB100-91714"	"Claudins  make up tight junction strands."
"MET"	"c-Met-M-QC_GBL1114664.txt"	"c-Met-M-QC"	"**Used for QC**"	"Mouse"	"CST"	"3127"	"Met, a high affinity tyrosine kinase receptor for hepatocyte growth factor (HGF, also known as scatter factor) is a disulfide-linked heterodimer made of 45 kDa ?- and 145 kDa ?-subunits. The ?-subunit and the amino-terminal region of the ?-subunit form the extracellular domain. The remainder of the ?-chain spans the plasma membrane and contains a cytoplasmic region with tyrosine kinase activity. Interaction of Met with HGF results in autophosphorylation at multiple tyrosines, which recruit several downstream signaling components, including Gab1, c-Cbl, and PI3 kinase. These fundamental events are important for all of the biological functions involving Met kinase activity. The addition of a phosphate at cytoplasmic Tyr1003 is essential for Met protein ubiquitination and degradation. Phosphorylation at Tyr1234/1235 in the Met kinase domain is critical for kinase activation. Phosphorylation at Tyr1349 in the Met cytoplasmic domain provides a direct binding site for Gab1. Research studies have shown that altered Met levels and/or tyrosine kinase activities are found in several types of tumors, including renal, colon, and breast. Thus, investigators have concluded that Met is an attractive potential cancer therapeutic and diagnostic target."
"MET"	"c-Met_pY1235-R-V_GBL1114565.txt"	"c-Met_pY1235-R-V"	"Validated"	"Rabbit"	"CST"	"3129"	"Tyrosine kinase receptor for hepatocyte growth factor"
"MYC"	"c-Myc-R-C_GBL1114629.txt"	"c-Myc-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9402"	"Members of the Myc/Max/Mad network function as transcriptional regulators invlolving in proliferation, differentiation and apoptosis"
"COL6A1"	"Collagen_VI-R-V_GBL1114509.txt"	"Collagen_VI-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"SC-20649"	"Collagens are fibrous, extracellular matrix proteins play a role in cell adhesion, important for maintaining normal tissue architecture and function."
"RAF1"	"C-Raf-R-V_GBL1114577.txt"	"C-Raf-R-V"	"Validated"	"Rabbit"	"Millipore"	"05-739"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"RAF1"	"C-Raf_pS338-R-V_GBL1114510.txt"	"C-Raf_pS338-R-V"	"Under Evaluation"	"Rabbit"	"CST"	"9427"	"One of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway "
"CCNB1"	"Cyclin_B1-R-V_GBL1114511.txt"	"Cyclin_B1-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1495-1"	"Cyclin B1 regulates mitosis. Cyclin B1 levels rise during S phase and G2, and peak at mitosis. "
"CCND1"	"Cyclin_D1-R-V_GBL1114512.txt"	"Cyclin_D1-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"SC-718"	"Cyclin D corresponds to a putative human oncogene. It regulates phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors"
"CCNE1"	"Cyclin_E1-M-V_GBL1114650.txt"	"Cyclin_E1-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"SC-247"	"Cyclin E has been found to be associated with the transcription factor E2F in a temporally regulated manner. The cyclin E/E2F complex is detected primarily during the G1 phase of the cell cycle and decreases as cells enter S phase. E2F is known to be a critical transcription factor for expression of several S phase specific proteins."
"CCNE2"	"Cyclin_E2-R-C_GBL1114513.txt"	"Cyclin_E2-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1142"	"Controls cell cycle at late G1 and early S phase"
"PARK7"	"DJ-1-R-E_GBL1114588.txt"	"DJ-1-R-E"	"Validated"	"Rabbit"	"Abcam"	"ab76008"	"May involved in regulation of PTEN expression"
"DVL3"	"Dvl3-R-V_GBL1114596.txt"	"Dvl3-R-V"	"Validated"	"Rabbit"	"CST"	"3218"	"Intermediates of Wnt signaling pathways"
"CDH1"	"E-Cadherin-R-V_GBL1114614.txt"	"E-Cadherin-R-V"	"Validated"	"Rabbit"	"CST"	"4065"	"A member of transmembrane glycoprotein superfamily, Mediate calcium-dependent cell-cell adhesion and normal tissue development. "
"EEF2"	"eEF2-R-C_GBL1114604.txt"	"eEF2-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2332"	"Eukaryotic elongation factor 2 (eEF2) catalyzes the translocation of peptidyl-tRNA from the A site to the P site on the ribosome. Insulin induces rapid dephosphorylation of eEF2 through mTOR signaling."
"EEF2K"	"eEF2K-R-V_GBL1114605.txt"	"eEF2K-R-V"	"Validated"	"Rabbit"	"CST"	"3692"	"Eukaryotic elongation factor 2 kinase (eEF2k) phosphorylates and inactivates eEF2, resulting in the inhibition of peptide-chain elongation.p90RSK and p70 S6 kinase phosphorylate and inactivate eEF2k."
"EGFR"	"EGFR-R-V_GBL1114616.txt"	"EGFR-R-V"	"Validated"	"Rabbit"	"CST"	"2232"	"Epidermal growth factor receptor (EGFR), Tyrosine Kinase Receptor"
"EGFR"	"EGFR_pY1068-R-C_GBL1114399.txt"	"EGFR_pY1068-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2234"	"Epidermal growth factor receptor (EGFR), Tyrosine Kinase Receptor"
"EGFR"	"EGFR_pY1173-R-V_GBL1114514.txt"	"EGFR_pY1173-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1124"	"Epidermal growth factor receptor (EGFR), Tyrosine Kinase Receptor"
"EIF4E"	"eIF4E-R-V_GBL1114564.txt"	"eIF4E-R-V"	"Valid"	"Rabbit"	"CST"	"9742"	"Eukaryotic initiation factor 4E (eIF4E) binds to the mRNA cap structure to mediate the initiation of translation (1,2). eIF4E interacts with eIF4G, a scaffold protein that promotes assembly of eIF4E and eIF4A into the eIF4F complex (2). eIF4B is thought to assist the eIF4F complex in translation initiation. Upon activation by mitogenic and/or stress stimuli mediated by Erk and p38 MAPK, Mnk1 phosphorylates eIF4E at Ser209 in vivo (3,4). Two Erk and p38 MAPK phosphorylation sites in mouse Mnk1 (Thr197 and Thr202) are essential for Mnk1 kinase activity (3). The carboxy-terminal region of eIF4G also contains serum-stimulated phosphorylation sites, including Ser1108, Ser1148, and Ser1192 (5). Phosphorylation at these sites is blocked by the PI3 kinase inhibitor LY294002 and by the FRAP/mTOR inhibitor rapamycin."
"EIF4G1"	"eIF4G-R-C_GBL1114619.txt"	"eIF4G-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2498"	"Translation initiation factor"
"ESR1"	"ER-alpha-R-V_GBL1114400.txt"	"ER-alpha-R-V"	"Validated"	"Rabbit"	"Lab Vision"	"RM-9101-S"	"Estrogen receptor, Transcription Factor"
"ESR1"	"ER-alpha_pS118-R-V_GBL1114516.txt"	"ER-alpha_pS118-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1091-1"	"Estrogen receptor, Transcription Factor"
"ERCC1"	"ERCC1-M-V_GBL1114651.txt"	"ERCC1-M-V"	"**Used for QC**"	"Mouse"	"Lab Vision"	"MS-671-PO"	"Involved in DNA repaire"
"MAPK1"	"ERK2-R-E_GBL1114517.txt"	"ERK2-R-E"	"Under Evaluation"	"Rabbit"	"Santa Cruz"	"sc-154"	"Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42)."
"ETS1"	"ETS-1-R-V_GBL1114635.txt"	"ETS-1-R-V"	"Validated"	"Rabbit"	"BethYl"	"A303-501A"	"Ets-1 is a member of the ETS family of transcription factors"
"FASN"	"FASN-R-V_GBL1114632.txt"	"FASN-R-V"	"Validated"	"Rabbit"	"CST"	"3180"	"Fatty acid synthase (FASN) catalyzes the synthesis of long-chain fatty acids from acetyl-CoA and malonyl-CoA. Indicated as a poor prognosis in breast and prostate cancer. "
"FN1"	"Fibronectin-R-V_GBL1114518.txt"	"Fibronectin-R-V"	"Use with Caution"	"Rabbit"	"Epitomics"	"1574-1"	"Involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape"
"FOXM1"	"FoxM1-R-V_GBL1114618.txt"	"FoxM1-R-V"	"Validated"	"Rabbit"	"CST"	"5436"	"A forkhead box family transcription factor that regulates a number of genes throughout the cell cycle to help control DNA replication, mitosis and cell proliferation"
"FOXO3"	"FOXO3a-R-C_GBL1114690.txt"	"FOXO3a-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9467"	"Transcription Factor, involved in tyrosin kinase receptor and PI3K/AKT pathway"
"FOXO3"	"FOXO3a_pS318_S321-R-C_GBL1114525.txt"	"FOXO3a_pS318_S321-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9465"	"Transcription Factor, involved in tyrosin kinase receptor and PI3K/AKT pathway"
"G6PD"	"G6PD-M-V_GBL1114681.txt"	"G6PD-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-373887"	"Plays an important role in the pentose phosphate pathway"
"GAB2"	"GAB2-R-V_GBL1114597.txt"	"GAB2-R-V"	"Validated"	"Rabbit"	"CST"	"3239"	"Adaptor proteins recruited by a wide variety of receptor tyrosine kinases (RTKs) such as EGFR, HGFR, insulin receptor, cytokine receptor and B cell antigen receptors"
"GAPDH"	"GAPDH-M-C_GBL1114652.txt"	"GAPDH-M-C"	"Use with Caution"	"Mouse"	"Ambion"	"AM4300"	"Glyceraldehyde 3-phosphate dehydrogenase"
"GATA3"	"GATA3-M-V_GBL1114665.txt"	"GATA3-M-V"	"Validated"	"Mouse"	"BD Biosciences"	"558686"	"Transcription factor"
"GSK3A GSK3B"	"GSK3-alpha-beta-M-V_GBL1114653.txt"	"GSK3-alpha-beta-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"SC-7291"	"An enzyme that regulates glycogen synthesis in response to insulin, Also involved in Wnt signaling"
"GSK3A GSK3B"	"GSK3-alpha-beta_pS21_S9-R-V_GBL1114526.txt"	"GSK3-alpha-beta_pS21_S9-R-V"	"Validated"	"Rabbit"	"CST"	"9331"	"An enzyme that regulates glycogen synthesis in response to insulin, Also involved in Wnt signaling"
"GSK3A GSK3B"	"GSK3_pS9-R-V_GBL1114611.txt"	"GSK3_pS9-R-V"	"Validated"	"Rabbit"	"CST"	"9336"	"An enzyme that regulates glycogen synthesis in response to insulin, Also involved in Wnt signaling"
"ERBB2"	"HER2-M-V_GBL1114675.txt"	"HER2-M-V"	"Validated"	"Mouse"	"Lab Vision"	"MS-325-P1"	"The ErbB-2 proto-oncogene product"
"ERBB2"	"HER2_pY1248-R-C_GBL1114608.txt"	"HER2_pY1248-R-C"	"Use with Caution"	"Rabbit"	"Upstate (Millipore)"	"06-229"	"The ErbB-2 proto-oncogene product"
"ERBB3"	"HER3-R-V_GBL1114592.txt"	"HER3-R-V"	"Validated"	"Mouse"	"Lab Vision"	"MS-201-P1ABX"	"A member of the ErbB receptor protein tyrosine kinase family, but it lacks tyrosine kinase activity"
"ERBB3"	"HER3_pY1289-R-C_GBL1114566.txt"	"HER3_pY1289-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4791"	"A member of the ErbB receptor protein tyrosine kinase family, but it lacks tyrosine kinase activity"
"NRG1"	"Heregulin-R-V_GBL1114587.txt"	"Heregulin-R-V"	"Validated"	"Rabbit"	"CST"	"2573"	"A soluble growth factor synthesized as a transmembrane precursor molecule involved in HRG-ErbB3/ErbB4 signaling to regulate cell proliferation, differentiation, invasion, and survival of both normal and malignant tissues"
"HSPA1A"	"HSP70-R-C_GBL1114527.txt"	"HSP70-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4872"	"A molecular chaperone expressed constitutively under normal conditions to maintain protein homeostasis and are induced upon environmental stress"
"IGFBP2"	"IGFBP2-R-V_GBL1114528.txt"	"IGFBP2-R-V"	"Validated"	"Rabbit"	"CST"	"3922"	"Insulin-like growth factor-binding proteins (IGFBPs), Tyrosine kinase receptor"
"INPP4B"	"INPP4B-R-V_GBL1114523.txt"	"INPP4B-R-V"	"Under Evaluation"	"Goat"	"Santa Cruz"	"SC-12318"	"The inositol polyphosphate 4-phosphatases catalyze the hydrolysis of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate."
"IRS1"	"IRS1-R-V_GBL1114576.txt"	"IRS1-R-V"	"Validated"	"Rabbit"	"Upstate (Millipore)"	"06-248"	"Insulin receptor substrate (IRS) molecules are key mediators in insulin signaling and play a central role in maintaining basic cellular functions such as growth, survival, and metabolism. Involves in PI3K pathway."
"COPS5"	"JAB1-M-C_GBL1114688.txt"	"JAB1-M-C"	"Use with Caution"	"Mouse"	"Santa Cruz"	"sc-13157"	"JAB1is the coactivator of Jun, (designated as Jun-activation domain-binding protein), interacts with c-Jun and Jun D, but not with Jun B or v-Jun. This interaction enhances the transactivating ability of Jun proteins by stabilizing their binding to the TRE."
"MAPK9"	"JNK2-R-C_GBL1114529.txt"	"JNK2-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4672"	"The stress-activated protein kinase, Belong to MAPK pathway (MKK4/7)"
"MAPK8"	"JNK_pT183_pY185-R-V_GBL1114586.txt"	"JNK_pT183_pY185-R-V"	"Validated"	"Rabbit"	"CST"	"4668"	"The stress-activated protein kinase, Belong to MAPK pathway (MKK4/7)"
"XRCC5"	"Ku80-R-C_GBL1114591.txt"	"Ku80-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2180"	"Functions as the DNA-binding regulatory component of DNA-dependent protein kinase (DNA-PK) involving in DNA repaire"
"LCK"	"Lck-R-V_GBL1114530.txt"	"Lck-R-V"	"Validated"	"Rabbit"	"CST"	"2752"	"A member of Src family of protein tyrosine kinases"
"STK11"	"LKB1-M-E_GBL1114654.txt"	"LKB1-M-E"	"Under Evaluation"	"Mouse"	"Abcam"	"ab15095"	"Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor."
"MAPK1 MAPK3"	"MAPK_pT202_Y204-R-V_GBL1114463.txt"	"MAPK_pT202_Y204-R-V"	"Validated"	"Rabbit"	"CST"	"4377"	"MAPK pathway (Mitogen-activated protein kinases), Regulates cell growth and differentiation"
"MAP2K1"	"MEK1-R-V_GBL1114531.txt"	"MEK1-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1235-1"	"MAPK pathway (Mitogen-activated protein kinases), Regulates cell growth and differentiation"
"MAP2K1"	"MEK1_pS217_S221-R-V_GBL1114609.txt"	"MEK1_pS217_S221-R-V"	"Validated"	"Rabbit"	"CST"	"9154"	"MAPK pathway (Mitogen-activated protein kinases), Regulates cell growth and differentiation"
"ERRFI1"	"MIG-6-M-V_GBL1114676.txt"	"MIG-6-M-V"	"Validated"	"Mouse"	"Sigma"	"WH0054206M1"	"ERRFI1 (MIG6) is a cytoplasmic protein whose expression is upregulated with cell growth "
"MRE11A"	"Mre11-R-C_GBL1114532.txt"	"Mre11-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4847"	"A central part of a multisubunit nuclease composed of Mre11, Rad50 and Nbs1 (MRN), Plays a critical role in sensing, processing and repairing DNA double strand breaks"
"MSH2"	"MSH2-M-V_GBL1114666.txt"	"MSH2-M-V"	"Validated"	"Mouse"	"CST"	"2850"	"MSH2 (MutS homologue 2) forms the hMutS-_ dimer with MSH6 and is an essential component of the mismatch DNA repair process. "
"MSH6"	"MSH6-R-C_GBL1114606.txt"	"MSH6-R-C"	"Use with Caution"	"Rabbit"	"Novus Biologicals"	"22030002"	"MSH6 is a mismatch-repair protein. It forms the hMutS-_ dimer with MSH2 and is an essential component of the mismatch DNA repair process. It plays a role in tumor suppression."
"MTOR"	"mTOR-R-V_GBL1114533.txt"	"mTOR-R-V"	"Validated"	"Rabbit"	"CST"	"2983"	"The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase, a major component of PI3K/AKT pathway"
"MTOR"	"mTOR_pS2448-R-C_GBL1114534.txt"	"mTOR_pS2448-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2971"	"The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase, a major component of PI3K/AKT pathway"
"MYH11"	"MYH11-R-V_GBL1114627.txt"	"MYH11-R-V"	"Validated"	"Rabbit"	"SDI / Novus"	"21370002"	"Myosin II forms bipolar filaments that interact with actin filaments to produce contraction."
"MYH9"	"Myosin-IIa_pS1943-R-V_GBL1114633.txt"	"Myosin-IIa_pS1943-R-V"	"Validated"	"Rabbit"	"CST"	"5026"	"Non muscle myosin is an actin-based motor protein essential to cell motility, cell division, migration, adhesion, and polarity"
"CDH2"	"N-Cadherin-R-V_GBL1114464.txt"	"N-Cadherin-R-V"	"Validated"	"Rabbit"	"CST"	"4061"	"A member of transmembrane glycoprotein superfamily, Mediate calcium-dependent cell-cell adhesion and normal tissue development. "
"NDRG1"	"NDRG1_pT346-R-V_GBL1114621.txt"	"NDRG1_pT346-R-V"	"Validated"	"Rabbit"	"CST"	"3217"	"A member of the NDRG family functions in growth, differentiation, and cell survival "
"NF2"	"NF2-R-C_GBL1114603.txt"	"NF2-R-C"	"Use with Caution"	"Rabbit"	"SDI"	"2271.00.02"	"Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals"
"NFKB1"	"NF-kB-p65_pS536-R-C_GBL1114535.txt"	"NF-kB-p65_pS536-R-C"	"Use with Caution"	"Rabbit"	"CST"	"3033"	"Transcription factors of the nuclear factor _ B (NF-_B)/Rel family play a pivotal role in inflammatory and immune responses "
"NOTCH1"	"Notch1-R-V_GBL1114607.txt"	"Notch1-R-V"	"Validated"	"Rabbit"	"CST"	"3268"	"A member of transmembrane receptor family that play important roles in development and the determination of cell fate "
"NRAS"	"N-Ras-M-V_GBL1114679.txt"	"N-Ras-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-31"	"The three Ras oncogenes, H-Ras, K-Ras and N-Ras, encode proteins with GTP/GDP binding and GTPase activity. Activates MAPK pathway."
"CDKN1A"	"p21-R-V_GBL1114536.txt"	"p21-R-V"	"Validated"	"Rabbit"	"Santa Cruz"	"SC-397"	"p21 is a potent, tight-binding inhibitor of Cdks and can inhibit the phosphorylation of Rb by cyclin A-Cdk 2, cyclin E-Cdk2, cyclin D1-Cdk4 and cyclin D2-Cdk4 complexes. Involves in p53 pathway and induces cell cycle arrest."
"CDKN1B"	"p27-R-V_GBL1114589.txt"	"p27-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1591-1"	"Regulates cell cycle arrest at G1 phase"
"CDKN1B"	"p27_pT157-R-C_GBL1114581.txt"	"p27_pT157-R-C"	"Use with Caution"	"Rabbit"	"R&D"	"AF1555"	"Regulates cell cycle arrest at G1 phase"
"CDKN1B"	"p27_pT198-R-V_GBL1114583.txt"	"p27_pT198-R-V"	"Validated"	"Rabbit"	"Abcam"	"ab64949"	"Involved in cell cycle arrest at G1 phase."
"MAPK14"	"p38_MAPK-R-V_GBL1114537.txt"	"p38_MAPK-R-V"	"Validated"	"Rabbit"	"CST"	"9212"	" A member of MAPKs. MKK3, MKK6, and SEK phosphorylate and activate p38 MAPK"
"MAPK14"	"p38_pT180_Y182-R-V_GBL1114539.txt"	"p38_pT180_Y182-R-V"	"Validated"	"Rabbit"	"CST"	"9211"	" A member of MAPKs. MKK3, MKK6, and SEK phosphorylate and activate p38 MAPK"
"TP53"	"p53-R-E_GBL1114540.txt"	"p53-R-E"	"Under Evaluation"	"Rabbit"	"CST"	"9282"	"Tumor suppressor and Transcription Factor, Regulates cell cycle arrest and apoptosis and DNA repair "
"SQSTM1"	"p62-LCK-ligand-M-C_GBL1114682.txt"	"p62-LCK-ligand-M-C"	"Under Evaluation"	"Mouse"	"BD Transduction Lab"	"610833"	"p62 lck ligand (zeta-interacting protein (ZIP)) is a cytoplasmic protein that binds to the SH2 domain of lck. It interacts with PKC_.."
"RPS6KB1"	"p70S6K-R-V_GBL1114541.txt"	"p70S6K-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1494-1"	"Mitogen-activated Ser/Thr protein kinase, Involved in PI3K, MAPK and PKC pathways"
"RPS6KB1"	"p70S6K_pT389-R-V_GBL1114542.txt"	"p70S6K_pT389-R-V"	"Validated"	"Rabbit"	"CST"	"9205"	"Mitogen-activated Ser/Thr protein kinase, Involved in PI3K, MAPK and PKC pathways"
"RPS6KA1"	"p90RSK-R-C_GBL1114569.txt"	"p90RSK-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9347"	"The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases involving in MAPK and PI3K signaling"
"RPS6KA1"	"p90RSK_pT359_S363-R-C_GBL1114571.txt"	"p90RSK_pT359_S363-R-C"	"Use with Caution"	"Rabbit"	"CST"	"9344"	"The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases involving in MAPK and PI3K signaling"
"SERPINE1"	"PAI-1-M-E_GBL1114655.txt"	"PAI-1-M-E"	"Under Evaluation"	"Mouse"	"BD Biosciences"	"612024"	"PAI-1 is a glycoprotein involves in tissue plasminogen activator (tPA) and urokinase PA (uPA) signaling"
"PARP1"	"PARP1-R-V_GBL1114639.txt"	"PARP1-R-V"	"Valid"	"Rabbit"	"Santa Cruz"	"sc-7150"	"Poly(ADP-ribose) polymerase-1 (PARP-1), also designated PARP, is a nuclear DNA-binding zinc finger protein that influences DNA repair, DNA replication, modulation of chromatin structure, and apoptosis. In response to genotoxic stress, PARP-1 catalyzes the transfer of ADP-ribose units from NAD(+) to a number of acceptor molecules including chromatin. PARP-1 recognizes DNA strand interruptions and can complex with RNA and negatively regulate transcription. Actinomycin D- and etoposide-dependent induction of caspases mediates cleavage of PARP-1 into a p89 fragment that traverses into the cytoplasm. Apoptosis-inducing factor (AIF) translocation from the mitochondria to the nucleus is PARP-1-dependent and is necessary for PARP-1-dependent cell death. PARP-1 deficiencies lead to chromosomal instability due to higher frequencies of chromosome fusions and aneuploidy, suggesting that poly(ADP-ribosyl)ation contributes to the efficient maintenance of genome integrity. PARP-2 is part of the base excision repair (BER) pathway, catalyzing the poly(ADP-ribosy)lation of nuclear proteins. PARP-2 is a nuclear, DNA-binding protein which interacts with PARP-1. PARP-2 is present in actively dividing tissues with highest levels in the kidney, skeletal muscle, liver, heart and spleen."
"PARP1"	"PARP_cleaved-M-QC_GBL1114656.txt"	"PARP_cleaved-M-QC"	"**Used for QC**"	"Mouse"	"CST"	"9546"	"PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress. This protein can be cleaved by many ICE-like caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. In human PARP, the cleavage occurs between Asp214 and Gly215, which separates the PARP amino-terminal DNA binding domain (24 kDa) from the carboxy-terminal catalytic domain (89 kDa). PARP helps cells to maintain their viability; cleavage of PARP facilitates cellular disassembly and serves as a marker of cells undergoing apoptosis."
"PXN"	"Paxillin-R-C_GBL1114543.txt"	"Paxillin-R-C"	"Use with Caution"	"Rabbit"	"Epitomics"	"1500-1"	"Involved in actin-membrane attachment, Regulates integrin signaling"
"CDH3"	"P-Cadherin-R-C_GBL1114691.txt"	"P-Cadherin-R-C"	"Under Evaluation"	"Rabbit"	"CST"	"2130"	"A member of transmembrane glycoprotein superfamily, Mediate calcium-dependent cell-cell adhesion and normal tissue development. "
"PCNA"	"PCNA-M-C_GBL1114657.txt"	"PCNA-M-C"	"Use with Caution"	"Mouse"	"Abcam"	"ab29"	"Involves in DNA repair"
"PDCD4"	"PDCD4-R-C_GBL1114579.txt"	"PDCD4-R-C"	"Use with Caution"	"Rabbit"	"Rockland"	"600-401-965"	"Pdcd4 directly inhibits the helicase activity of eukaryotic translation initiation factor 4A (eIF4A), a component of the translation initiation complex. Pdcd4 also suppresses the transactivation of activator protein-1 (AP-1)-responsive promoters by c-Jun. Pdcd4 contains two Akt phosphorylation sites, one at Ser67 and the other at Ser457. The phosphorylation of Pdcd4 by Akt causes nuclear translocation of Pdcd4 and a significant decrease in the ability of Pdcd4 to interfere with the transactivation of AP-1-responsive promoters by c-Jun."
"PDK1"	"PDK1-R-V_GBL1114544.txt"	"PDK1-R-V"	"Validated"	"Rabbit"	"CST"	"3062"	"Phosphoinositide-dependent protein kinase 1, involved in PI3K/AKT and PKC signaling"
"PDK1"	"PDK1_pS241-R-V_GBL1114545.txt"	"PDK1_pS241-R-V"	"Validated"	"Rabbit"	"CST"	"3061"	"Phosphoinositide-dependent protein kinase 1, involved in PI3K/AKT and PKC signaling"
"PEA15"	"PEA15-R-V_GBL1114600.txt"	"PEA15-R-V"	"Validated"	"Rabbit"	"CST"	"2780"	"Coordinate cell growth, death, and glucose utilization. Involved in MAPK  signaling"
"PEA15"	"PEA15_pS116-R-V_GBL1114601.txt"	"PEA15_pS116-R-V"	"Validated"	"Rabbit"	"Invitrogen"	"44-836G"	"Implicated in the regulation of multiple cellular processes including apoptosis, integrin activation, and insulin-sensitive glucose transport in insulin-responsive cells. Its activation mediated through binding to multiple proteins, including ERK1&2, RSK2, Akt, FADD, and Caspase-8."
"PIK3CA "	"PI3K-p110-alpha-R-C_GBL1114578.txt"	"PI3K-p110-alpha-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4255"	"One of the of the catalytic subunit of PI3K"
"PIK3R1 PIK3R2"	"PI3K-p85-R-V_GBL1114546.txt"	"PI3K-p85-R-V"	"Validated"	"Rabbit"	"Upstate (Millipore)"	"06-195"	"PI3K p85 regulatory subunit"
"PRKCA "	"PKC-alpha-M-V_GBL1114658.txt"	"PKC-alpha-M-V"	"Validated"	"Mouse"	"Upstate (Millipore)"	"05-154"	"PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions "
"PRKCA "	"PKC-alpha_pS657-R-C_GBL1114547.txt"	"PKC-alpha_pS657-R-C"	"Use with Caution"	"Rabbit"	"Upstate (Millipore)"	"06-822"	"PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions "
"PRKCD"	"PKC-delta_pS664-R-V_GBL1114595.txt"	"PKC-delta_pS664-R-V"	"Validated"	"Rabbit"	"Millipore"	"07-875"	"PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters."
"PRKCB"	"PKC-pan_BetaII_pS660-R-V_GBL1114625.txt"	"PKC-pan_BetaII_pS660-R-V"	"Validated"	"Rabbit"	"CST"	"9371"	"Activation of protein kinase C (PKC) is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction"
"PGR"	"PR-R-V_GBL1114548.txt"	"PR-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1483-1"	"Progesterone receptor, Transcription Factor"
"AKT1S1"	"PRAS40_pT246-R-V_GBL1114567.txt"	"PRAS40_pT246-R-V"	"Validated"	"Rabbit"	"Biosource"	"441100G"	"PRAS40 is a 14-3-3 binding protein that reacts with insulin. PRAS40 is phosphorylated by AKT"
"PRDX1"	"PRDX1-R-V_GBL1114637.txt"	"PRDX1-R-V"	"Under Evaluation"	"Rabbit"	"Sigma/Atlas"	"HPA007730"	"A member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. "
"PREX1"	"PREX1-R-E_GBL1114636.txt"	"PREX1-R-E"	"Under Evaluation"	"Rabbit"	"Abcam"	"ab102739"	"Downstream of Heterotrimric G proteins (Guanine nucleotide exchange factor)"
"PTEN"	"PTEN-R-V_GBL1114550.txt"	"PTEN-R-V"	"Validated"	"Rabbit"	"CST"	"9552"	"A lipid and protein phosphatase, a tumor suppressor, Major negative regulator of PI3K/AKT signaling"
"RAB11A RAB11B"	"Rab11-R-E_GBL1114689.txt"	"Rab11-R-E"	"Under Evaluation"	"Rabbit"	"CST"	"3539"	"Rab11 family posseses small Ras-like GTPase activity. Rab11 family includes Rab11a, Rab11b and Rab25 "
"RAB25"	"Rab25-R-V_GBL1114630.txt"	"Rab25-R-V"	"Validated"	"Rabbit"	"CST"	"4314"	"A member of Rab11 family posseses small Ras-like GTPase activity.  Increased Rab25 expression is associated with aggressive growth in ovarian and breast cancer, where Rab25 may inhibit apoptosis and promote cancer cell proliferation and invasion through regulation of vesicle transport and cellular motility."
"RAD50"	"Rad50-M-V_GBL1114673.txt"	"Rad50-M-V"	"Validated"	"Mouse"	"Millipore"	"05-525"	"Involved in DNA double-strand break repair"
"RAD51"	"Rad51-R-V_GBL1114638.txt"	"Rad51-R-V"	"Under Evaluation"	"Mouse"	"Chem Biotech"	"na 71"	"Involved in DNA double-strand break repair"
"RPTOR"	"Raptor-R-V_GBL1114622.txt"	"Raptor-R-V"	"Validated"	"Rabbit"	"CST"	"2280"	"The regulatory associated protein of mTOR (Raptor) was identified as an mTOR binding partner that mediates mTOR signaling to downstream targets. Recently raptor has been identified as a direct substrate of the AMP-activated protein kinase (AMPK). "
"RB1"	"Rb-M-QC_GBL1114659.txt"	"Rb-M-QC"	"**Used for QC**"	"Mouse"	"CST"	"9309"	"The retinoblastoma tumor suppressor protein Rb regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle. Rb has three functionally distinct binding domains and interacts with critical regulatory proteins including the E2F family of transcription factors, c-Abl tyrosine kinase, and proteins with a conserved LXCXE motif (2-4). Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo."
"RBM15"	"RBM15-R-V_GBL1114626.txt"	"RBM15-R-V"	"Validated"	"Rabbit"	"SDI / Novus"	"21390002"	"RBM15, have repressor function in several signaling pathways"
"RB1"	"Rb_pS807_S811-R-V_GBL1114549.txt"	"Rb_pS807_S811-R-V"	"Validated"	"Rabbit"	"CST"	"9308"	"The retinoblastoma tumor suppressor protein regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle"
"RICTOR"	"Rictor-R-C_GBL1114623.txt"	"Rictor-R-C"	"UsewithCaution"	"Rabbit"	"CST"	"2114"	"Rapamycin-insensitive companion of mTOR mediate rictor-mTOR signaling and phosphorylates Akt/PKB on Ser473 required for the full activation of AKT"
"RICTOR"	"Rictor_pT1135-R-V_GBL1114624.txt"	"Rictor_pT1135-R-V"	"Validated"	"Rabbit"	"CST"	"3806"	"Rapamycin-insensitive companion of mTOR mediate rictor-mTOR signaling and phosphorylates Akt/PKB on Ser473 required for the full activation of AKT"
"RPS6"	"S6-R-E_GBL1114552.txt"	"S6-R-E"	"Under Evaluation"	"Rabbit"	"CST"	"2217"	"Down stream of PI3K/AKT/mTOR/p70 S6 kinase, Involved in growth factors and mitogens induced protein translation"
"RPS6"	"S6_pS235_S236-R-V_GBL1114553.txt"	"S6_pS235_S236-R-V"	"Validated"	"Rabbit"	"CST"	"2211"	"Down stream of PI3K/AKT/mTOR/p70 S6 kinase, Involved in growth factors and mitogens induced protein translation"
"RPS6"	"S6_pS240_S244-R-V_GBL1114554.txt"	"S6_pS240_S244-R-V"	"Validated"	"Rabbit"	"CST"	"2215"	"Down stream of PI3K/AKT/mTOR/p70 S6 kinase, Involved in growth factors and mitogens induced protein translation"
"SCD"	"SCD-M-V_GBL1114677.txt"	"SCD-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-58420"	"Stearoyl-CoA desaturase (SCD) is a microsomal enzyme required for the synthesis of oleate and palmitoleate, which are the major monounsaturated fatty acids of membrane phospholipids, triglycerides and cholesterol esters."
"SETD2"	"SETD2-R-QC_GBL1114602.txt"	"SETD2-R-QC"	"**Used for QC**"	"Rabbit"	"Abcam"	"ab69836"	"SETD2 is a Histone methyltransferase that methylates 'Lys-36' of histone H3. H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. Probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. Binds DNA at promoters. May also act as a transcription activator that binds to promoters. Binds to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression."
"SRSF1"	"SF2-M-V_GBL1114678.txt"	"SF2-M-V"	"Validated"	"Mouse"	"Invitrogen"	"32-4500"	"The SF proteins are essential splicing factors and also regulate alternative splicing of many pre-mRNAs."
"SHC1"	"Shc_pY317-R-E_GBL1114521.txt"	"Shc_pY317-R-E"	"Validated"	"Rabbit"	"CST"	"2431"	"Serves as a scaffold protein in signaling for a variety of receptor tyrosine kinases"
"DIABLO"	"Smac-M-QC_GBL1114660.txt"	"Smac-M-QC"	"**Used for QC**"	"Mouse"	"CST"	"2954"	"Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases. This interaction involves mainly the amino-terminal residues of Smac/Diablo with the BIR3 region of XIAP, supplemented with several other hydrophobic interactions between the helical structures of Smac/Diablo and other areas of BIR3."
"SMAD1"	"Smad1-R-V_GBL1114593.txt"	"Smad1-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1649-1"	"Mediates TGF beta signaling"
"SMAD3"	"Smad3-R-V_GBL1114575.txt"	"Smad3-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1735-1"	"Mediates TGF beta signaling"
"SMAD4"	"Smad4-M-V_GBL1114669.txt"	"Smad4-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-7966"	"Mediates TGF beta signaling"
"SNAI1"	"Snail-M-QC_GBL1114661.txt"	"Snail-M-QC"	"**Used for QC**"	"Mouse"	"CST"	"3895"	"Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells. Indeed, loss of E-cadherin expression is correlated with the invasive properties of some tumors and there is a considerable inverse correlation between Snail and E-cadherin mRNA levels in epithelial tumor cell lines. In addition, Snail blocks the cell cycle and confers resistance to cell death. Phosphorylation of Snail by GSK-3 and PAK1 regulates its stability, cellular localization and function."
"SRC"	"Src-M-V_GBL1114662.txt"	"Src-M-V"	"Validated"	"Mouse"	"Upstate (Millipore)"	"05-184"	"A member of Src family of protein tyrosine kinases"
"SRC"	"Src_pY416-R-C_GBL1114555.txt"	"Src_pY416-R-C"	"Use with Caution"	"Rabbit"	"CST"	"2101"	"A member of Src family of protein tyrosine kinases"
"SRC"	"Src_pY527-R-V_GBL1114556.txt"	"Src_pY527-R-V"	"Validated"	"Rabbit"	"CST"	"2105"	"A member of Src family of protein tyrosine kinases"
"STAT3"	"STAT3_pY705-R-V_GBL1114557.txt"	"STAT3_pY705-R-V"	"Validated"	"Rabbit"	"CST"	"9131"	"Signal transducer and activator of transcription 3 functions both in signal transduction and activation of transcription"
"STAT5A"	"STAT5-alpha-R-V_GBL1114558.txt"	"STAT5-alpha-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1289-1"	"Signal transducer and activator of transcription 5 functions both in signal transduction and activation of transcription"
"STMN1"	"Stathmin-R-V_GBL1114563.txt"	"Stathmin-R-V"	"Validated"	"Rabbit"	"Epitomics"	"1972-1"	"Ubiquitous cytosolic phosphoprotein"
"SYK"	"Syk-M-V_GBL1114674.txt"	"Syk-M-V"	"Validated"	"Mouse"	"Santa Cruz"	"sc-1240"	"One of several members of the protein kinase superfamily involved in PI3K and PLC signaling"
"WWTR1"	"TAZ-R-V_GBL1114572.txt"	"TAZ-R-V"	"Validated"	"Rabbit"	"CST"	"2149"	"Transcriptional co-activator"
"TFRC"	"TFRC-R-V_GBL1114628.txt"	"TFRC-R-V"	"Validated"	"Rabbit"	"SDI / Novus"	"22500002"	"Transferrin Receptor"
"TIGAR"	"TIGAR-R-V_GBL1114615.txt"	"TIGAR-R-V"	"Under Evaluation"	"Rabbit"	"Epitomics"	"S1711"	"Regulates p53 tumor suppresor pathway and glycolysis"
"TGM2"	"Transglutaminase-M-V_GBL1114667.txt"	"Transglutaminase-M-V"	"Validated"	"Mouse"	"Lab Vision"	"MS-224"	"Transglutaminases catalyze the posttranslational modification of proteins by transamidation of available glutamine residues. Reported to facilitate breast cancer metastasis."
"TSC1"	"TSC1-R-C_GBL1114620.txt"	"TSC1-R-C"	"Use with Caution"	"Rabbit"	"CST"	"4906"	"The tumor suppressor genes TSC1 encode hamartin functions as a GTPase-activating protein for the Ras-related small G protein Rheb and thus inhibits targets of rapamycin including mTOR to regulate G1 phase of the cell cycle, steroid hormone regulation, Rho activation and anchoring neuronal intermediate filaments to the actin cytoskeleton. "
"NKX2-1"	"TTF1-R-V_GBL1114610.txt"	"TTF1-R-V"	"Valid"	"Rabbit"	"Abcam"	"ab76013"	"TTF1 is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis."
"TSC2"	"Tuberin-R-E_GBL1114559.txt"	"Tuberin-R-E"	"Validated"	"Rabbit"	"Epitomics"	"1613-1"	"Tuberous sclerosis complex-2 (TSC2 also known as Tuberin) is a tumor suppressor that forms a complex with TSC1 (Hamartin ) and this complex is known to control various cellular functions including cell cycle, endocytosis, adhesion, and transcription. Involved in AKT/mTOR signaling. "
"TSC2"	"Tuberin_pT1462-R-V_GBL1114560.txt"	"Tuberin_pT1462-R-V"	"Validated"	"Rabbit"	"CST"	"3617"	"Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Involved in AKT/mTOR signaling. "
"KDR"	"VEGFR2-R-V_GBL1114561.txt"	"VEGFR2-R-V"	"Validated"	"Rabbit"	"CST"	"2479"	"A major receptor for VEGF-induced signaling in endothelial cells"
"VHL"	"VHL-M-QC_GBL1114663.txt"	"VHL-M-QC"	"Use with Caution"	"Mouse"	"BD Pharmingen"	"556347"	"Transfection Factor"
"XBP1"	"XBP1-G-C_GBL1114642.txt"	"XBP1-G-C"	"Use with Caution"	"Goat"	"Santa Cruz"	"sc-32136"	"The X-box binding protein-1 plays a role in regulation of expression of osteoblast-specific genes."
"XRCC1"	"XRCC1-R-E_GBL1114520.txt"	"XRCC1-R-E"	"Under Evaluation"	"Rabbit"	"CST"	"2735"	"A DNA repair protein important in both single strand break repair and base excision repair following damage from ionizing radiation and alkylating agents"
"YAP1"	"YAP-R-E_GBL1114573.txt"	"YAP-R-E"	"Under Evaluation"	"Rabbit"	"Santa Cruz"	"sc-15407"	"Involved in Src, AKT and MAPK signaling"
"YAP1"	"YAP_pS127-R-E_GBL1114574.txt"	"YAP_pS127-R-E"	"Under Evaluation"	"Rabbit"	"CST"	"4911"	"Involved in Src, AKT and MAPK signaling"
"YBX1"	"YB-1-R-V_GBL1114562.txt"	"YB-1-R-V"	"Validated"	"Rabbit"	"SDI"	"1725.00.02"	"Belongs to a family of evolutionarily conserved, multifunctional Y-box proteins that bind to DNA and RNA,  function as regulators of transcription, RNA metabolism, and protein synthesis"
"YBX1"	"YB-1_pS102-R-V_GBL1114580.txt"	"YB-1_pS102-R-V"	"Validated"	"Rabbit"	"CST"	"2900"	"Belongs to a family of evolutionarily conserved, multifunctional Y-box proteins that bind to DNA and RNA,  function as regulators of transcription, RNA metabolism, and protein synthesis"
